Adoptive immunotherapy for cancer: harnessing the T cell response (Q28262548)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6292222&resulttype=core&format=json

13 May 2020

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1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6292222&resulttype=core&format=json

13 May 2020

3

Steven A Rosenberg

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6292222&resulttype=core&format=json

13 May 2020

author name string

Mark E Dudley

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6292222&resulttype=core&format=json

Nature Reviews Immunology

13 May 2020

language of work or name

English

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publication date

22 March 2012

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published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6292222&resulttype=core&format=json

13 May 2020

volume

12

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6292222&resulttype=core&format=json

13 May 2020

issue

4

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6292222&resulttype=core&format=json

13 May 2020

page(s)

269-281

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6292222&resulttype=core&format=json

Intravital Imaging Reveals Distinct Dynamics for Natural Killer and CD8+ T Cells during Tumor Regression

13 May 2020

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A TCR targeting the HLA-A*0201-restricted epitope of MAGE-A3 recognizes multiple epitopes of the MAGE-A antigen superfamily in several types of cancer.

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Leukocyte composition of human breast cancer

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Targeting stroma to treat cancers

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Gene therapy using genetically modified lymphocytes targeting VEGFR-2 inhibits the growth of vascularized syngenic tumors in mice

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Antiangiogenic agents can increase lymphocyte infiltration into tumor and enhance the effectiveness of adoptive immunotherapy of cancer

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Targeting the tumour vasculature: insights from physiological angiogenesis

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Vaccine-stimulated, adoptively transferred CD8+ T cells traffic indiscriminately and ubiquitously while mediating specific tumor destruction.

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Tumor progression can occur despite the induction of very high levels of self/tumor antigen-specific CD8+ T cells in patients with melanoma

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Enhancing efficacy of recombinant anticancer vaccines with prime/boost regimens that use two different vectors

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Construction and characterization of a triple-recombinant vaccinia virus encoding B7-1, interleukin 12, and a model tumor antigen

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Recent advances in therapeutic cancer vaccines

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Cancer immunotherapy: moving beyond current vaccines

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Establishment and large-scale expansion of minimally cultured "young" tumor infiltrating lymphocytes for adoptive transfer therapy

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Clinical responses in a phase II study using adoptive transfer of short-term cultured tumor infiltration lymphocytes in metastatic melanoma patients

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Determinants of successful CD8+ T-cell adoptive immunotherapy for large established tumors in mice

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Exploring the genomes of cancer cells: progress and promise

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Antitumor activity and long-term fate of chimeric antigen receptor-positive T cells in patients with neuroblastoma

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Adoptive transfer of syngeneic T cells transduced with a chimeric antigen receptor that recognizes murine CD19 can eradicate lymphoma and normal B cells

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Genetic engineering of murine CD8+ and CD4+ T cells for preclinical adoptive immunotherapy studies.

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T-cell receptor gene therapy of established tumors in a murine melanoma model

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Cancer regression in patients after transfer of genetically engineered lymphocytes

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Virus-specific T cells engineered to coexpress tumor-specific receptors: persistence and antitumor activity in individuals with neuroblastoma

31 March 2020

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Control of HIV-1 immune escape by CD8 T cells expressing enhanced T-cell receptor

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The promise and potential pitfalls of chimeric antigen receptors

31 March 2020

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Case report of a serious adverse event following the administration of T cells transduced with a chimeric antigen receptor recognizing ERBB2

31 March 2020

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Bispecific antibodies engage T cells for antitumor immunotherapy

31 March 2020

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Genetically modulating T-cell function to target cancer.

31 March 2020

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A human memory T cell subset with stem cell-like properties

31 March 2020

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T cell-encoded CD80 and 4-1BBL induce auto- and transcostimulation, resulting in potent tumor rejection

31 March 2020

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Bcl-2 overexpression enhances tumor-specific T-cell survival

31 March 2020

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Tumor-targeted T cells modified to secrete IL-12 eradicate systemic tumors without need for prior conditioning

31 March 2020

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IL-12 triggers a programmatic change in dysfunctional myeloid-derived cells within mouse tumors.

31 March 2020

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Tumor-specific CD8+ T cells expressing interleukin-12 eradicate established cancers in lymphodepleted hosts

31 March 2020

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Transduction of tumor-specific T cells with CXCR2 chemokine receptor improves migration to tumor and antitumor immune responses

31 March 2020

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Lethal graft-versus-host disease in mouse models of T cell receptor gene therapy

31 March 2020

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Of Mice, Not Men: No Evidence for Graft-versus-Host Disease in Humans Receiving T-Cell Receptor–Transduced Autologous T Cells

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31 March 2020

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Transplantation of mouse HSCs genetically modified to express a CD4-restricted TCR results in long-term immunity that destroys tumors and initiates spontaneous autoimmunity

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31 March 2020

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Inducible apoptosis as a safety switch for adoptive cell therapy

31 March 2020

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Cyclophosphamide-facilitated adoptive immunotherapy of an established tumor depends on elimination of tumor-induced suppressor T cells

31 March 2020

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Hematopoietic stem cells promote the expansion and function of adoptively transferred antitumor CD8 T cells

31 March 2020

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Increased intensity lymphodepletion enhances tumor treatment efficacy of adoptively transferred tumor-specific T cells

31 March 2020

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Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes

31 March 2020

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Adoptive cell therapy for patients with metastatic melanoma: evaluation of intensive myeloablative chemoradiation preparative regimens

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Coordinated regulation of myeloid cells by tumours

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Synergy between T-cell immunity and inhibition of paracrine stimulation causes tumor rejection

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Removal of homeostatic cytokine sinks by lymphodepletion enhances the efficacy of adoptively transferred tumor-specific CD8+ T cells

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Microbial translocation augments the function of adoptively transferred self/tumor-specific CD8+ T cells via TLR4 signaling.

31 March 2020

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CD8+ T cell immunity against a tumor/self-antigen is augmented by CD4+ T helper cells and hindered by naturally occurring T regulatory cells.

31 March 2020

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Regulatory T cells selectively control CD8+ T cell effector pool size via IL-2 restriction

31 March 2020

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CD4+CD25+ T regulatory cells, immunotherapy of cancer, and interleukin-2.

31 March 2020

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The yin and yang of interleukin-2-mediated immunotherapy

31 March 2020

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Acquisition of full effector function in vitro paradoxically impairs the in vivo antitumor efficacy of adoptively transferred CD8+ T cells

31 March 2020

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Adoptive immunotherapy for cancer: building on success

31 March 2020

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31 March 2020

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CD8+ T-cell memory in tumor immunology and immunotherapy

31 March 2020

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Suppressors of cytokine signaling (SOCS) in T cell differentiation, maturation, and function

31 March 2020

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Adoptively transferred effector cells derived from naive rather than central memory CD8+ T cells mediate superior antitumor immunity.

31 March 2020

1 reference

Human effector CD8+ T cells derived from naive rather than memory subsets possess superior traits for adoptive immunotherapy.

31 March 2020

1 reference

Central memory self/tumor-reactive CD8+ T cells confer superior antitumor immunity compared with effector memory T cells

31 March 2020

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IL-15 enhances the in vivo antitumor activity of tumor-reactive CD8+ T cells

31 March 2020

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Adoptive transfer of effector CD8+ T cells derived from central memory cells establishes persistent T cell memory in primates

31 March 2020

1 reference

Engraftment of human central memory-derived effector CD8+ T cells in immunodeficient mice

31 March 2020

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Transferred melanoma-specific CD8+ T cells persist, mediate tumor regression, and acquire central memory phenotype

31 March 2020

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Host-reactive CD8+ memory stem cells in graft-versus-host disease

31 March 2020

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Wnt signaling arrests effector T cell differentiation and generates CD8+ memory stem cells

31 March 2020

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Harnessing the biology of IL-7 for therapeutic application

31 March 2020

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The B7 and CD28 receptor families

31 March 2020

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Repression of the DNA-binding inhibitor Id3 by Blimp-1 limits the formation of memory CD8+ T cells

31 March 2020

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IL-2 and IL-21 confer opposing differentiation programs to CD8+ T cells for adoptive immunotherapy

31 March 2020

1 reference

Reprogramming CD19-specific T cells with IL-21 signaling can improve adoptive immunotherapy of B-lineage malignancies.

31 March 2020

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Wnt/β-Catenin Signaling in T-Cell Immunity and Cancer Immunotherapy

31 March 2020

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Pharmacologic induction of CD8+ T cell memory: better living through chemistry

31 March 2020

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The role of CD4+ T cell responses in antitumor immunity

31 March 2020

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Naive tumor-specific CD4(+) T cells differentiated in vivo eradicate established melanoma.

31 March 2020

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Tumor-reactive CD4(+) T cells develop cytotoxic activity and eradicate large established melanoma after transfer into lymphopenic hosts

31 March 2020

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CD4(+) T cells eliminate MHC class II-negative cancer cells in vivo by indirect effects of IFN-gamma

31 March 2020

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Primary antitumor immune response mediated by CD4+ T cells

31 March 2020

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T helper 17 cells promote cytotoxic T cell activation in tumor immunity

31 March 2020

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Tumor-specific Th17-polarized cells eradicate large established melanoma

31 March 2020

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Th17 cells are long lived and retain a stem cell-like molecular signature

31 March 2020

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Both CD4 and CD8 T cells mediate equally effective in vivo tumor treatment when engineered with a highly avid TCR targeting tyrosinase.

31 March 2020

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Adoptive therapy using antigen-specific T-cell clones

31 March 2020

1 reference

Treatment of metastatic melanoma with autologous CD4+ T cells against NY-ESO-1

31 March 2020

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Helper T cell diversity and plasticity

31 March 2020

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The critical role of Th1-dominant immunity in tumor immunology.

31 March 2020

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Adoptive immunotherapy of cancer using CD4(+) T cells

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Does IL-17 promote tumor growth?

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Type 17 CD8+ T cells display enhanced antitumor immunity.

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Adoptive transfer of allogeneic tumor-specific T cells mediates effective regression of large tumors across major histocompatibility barriers.

31 March 2020

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Combination of targeted therapy and immunotherapy in melanoma

31 March 2020

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Programming tumor-reactive effector memory CD8+ T cells in vitro obviates the requirement for in vivo vaccination.

31 March 2020

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Tumor regression and autoimmunity after reversal of a functionally tolerant state of self-reactive CD8+ T cells.

31 March 2020

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Can Antitumor Immunity Help to Explain “Oncogene Addiction”?

31 March 2020

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CD4+ T Cells Contribute to the Remodeling of the Microenvironment Required for Sustained Tumor Regression upon Oncogene Inactivation

31 March 2020

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The BRAF-MAPK signaling pathway is essential for cancer-immune evasion in human melanoma cells

31 March 2020

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Selective BRAFV600E inhibition enhances T-cell recognition of melanoma without affecting lymphocyte function

31 March 2020

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Expression of tumour-specific antigens underlies cancer immunoediting

31 March 2020

1 reference

Induction of antigen-specific T cell anergy: An early event in the course of tumor progression

31 March 2020

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The central role of CD4(+) T cells in the antitumor immune response

31 March 2020

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Human TH17 cells are long-lived effector memory cells.

31 March 2020

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Recombinant virus vaccination against "self" antigens using anchor-fixed immunogens

31 March 2020

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12 December 2020

Identification of a CD11b(+)/Gr-1(+)/CD31(+) myeloid progenitor capable of activating or suppressing CD8(+) T cells.

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Autoimmunity and the immunotherapy of cancer: targeting the "self" to destroy the "other".

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Clinical experience with gene therapy and bispecific antibodies for T cell-based therapy of cancer

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12 December 2020

Passive Immunotherapy of Cancer in Animals and Man

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12 December 2020

Immunotherapy and chemotherapy of Moloney sarcoma virus-induced tumors in mice.

1 reference

12 December 2020

Specificity of adoptive chemoimmunotherapy of established syngeneic tumors

1 reference

12 December 2020

Active immunotherapy of cancer with a nonreplicating recombinant fowlpox virus encoding a model tumor-associated antigen

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12 December 2020

IL-2 enhances the function of recombinant poxvirus-based vaccines in the treatment of established pulmonary metastases

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12 December 2020

Therapeutic antitumor response after immunization with a recombinant adenovirus encoding a model tumor-associated antigen

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12 December 2020

Cytokine enhancement of DNA immunization leads to effective treatment of established pulmonary metastases.

1 reference

12 December 2020

IL-12 is an effective adjuvant to recombinant vaccinia virus-based tumor vaccines: enhancement by simultaneous B7-1 expression.

1 reference

12 December 2020

Enhancement of cellular immunity in melanoma patients immunized with a peptide from MART-1/Melan A

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Apoptotic death of CD8+ T lymphocytes after immunization: induction of a suppressive population of Mac-1+/Gr-1+ cells

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12 December 2020

Identifiers

DOI

10.1038/NRI3191

2 references

Consolidated OpenCitations Corpus – April 2017

42260

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6292222&resulttype=core&format=json

13 May 2020

42260

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6292222&resulttype=core&format=json

13 May 2020

PubMed publication ID

22437939

2 references

Consolidated OpenCitations Corpus – April 2017

42260

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6292222&resulttype=core&format=json