Inter-individual variability in levels of human microsomal protein and hepatocellularity per gram of liver (Q35825766)

10 August 2017

Inter-individual variability in levels of human microsomal protein and hepatocellularity per gram of liver (English)

1 reference

10 August 2017

Z E Wilson

1

1 reference

10 August 2017

A Rostami-Hodjegan

2

1 reference

10 August 2017

J L Burn

3

1 reference

10 August 2017

A Tooley

4

1 reference

10 August 2017

J Boyle

5

1 reference

10 August 2017

S W Ellis

6

1 reference

10 August 2017

G T Tucker

7

1 reference

10 August 2017

language of work or name

English

0 references

publication date

1 October 2003

1 reference

British Journal of Clinical Pharmacology

10 August 2017

1 reference

10 August 2017

56

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10 August 2017

4

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10 August 2017

433-440

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Variance of microsomal protein and cytochrome P450 2E1 and 3A forms in adult human liver

10 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884378

Protein measurement with the Folin phenol reagent

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884378

THE CARBON MONOXIDE-BINDING PIGMENT OF LIVER MICROSOMES. I. EVIDENCE FOR ITS HEMOPROTEIN NATURE

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884378

Prediction of hepatic metabolic clearance: comparison and assessment of prediction models

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884378

A commentary on the use of hepatocytes in drug metabolism studies during drug discovery and development

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884378

Cloning and characterization of a novel human dual flavin reductase

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884378

Microsomal prediction of in vivo clearance of CYP2C9 substrates in humans

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884378

Functional significance of a C-->A polymorphism in intron 1 of the cytochrome P450 CYP1A2 gene tested with caffeine

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884378

Quantitative prediction of in vivo drug clearance and drug interactions from in vitro data on metabolism, together with binding and transport

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884378

The prediction of human pharmacokinetic parameters from preclinical and in vitro metabolism data.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884378

Prediction of in vivo hepatic metabolic clearance of YM796 from in vitro data by use of human liver microsomes and recombinant P-450 isozymes

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884378

Cytochrome P450 2D6 variants in a Caucasian population: allele frequencies and phenotypic consequences

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884378

Utility of in vitro drug metabolism data in predicting in vivo metabolic clearance

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884378

Drug metabolism in human liver in vitro: establishment of a human liver bank.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884378

Characterisation of theophylline metabolism in human liver microsomes

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884378

The lipid composition of highly differentiated human hepatomas, with special reference to fatty acids

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884378

Comparative drug metabolism of diazepam in hepatocytes isolated from man, rat, monkey and dog.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884378

Microsomal cytochrome P-450-linked monooxygenase systems and lipid composition of human hepatocellular carcinoma

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884378

Quantitative determination of cytochrome P-450 in rat liver homogenate

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884378

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884378

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884378

7 Purification and properties of NADPH-Cytochrome P-450 reductase

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884378

Chapter 4 Preparation of Isolated Rat Liver Cells

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884378

Lack of impact of CYP1A2 genetic polymorphism (C/A polymorphism at position 734 in intron 1 and G/A polymorphism at position -2964 in the 5'-flanking region of CYP1A2) on the plasma concentration of haloperidol in smoking male Japanese with schizoph

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884378

In vitro/in vivo scaling of alprazolam metabolism by CYP3A4 and CYP3A5 in humans

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884378

An assessment of human liver-derived in vitro systems to predict the in vivo metabolism and clearance of almokalant

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884378

Standard liver volume in the Caucasian population.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884378

In vitro to in vivo extrapolation for trichloroethylene metabolism in humans.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884378

Calculation of child and adult standard liver volume for liver transplantation.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884378

Assessment of the predictive power of genotypes for the in-vivo catalytic function of CYP2D6 in a German population

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884378

Pigments of rat liver microsomes

22 October 2018

1 reference

12 December 2020

The Use of Humanin VitroMetabolic Parameters to Explore the Risk Assessment of Hazardous Compounds: The Case of Ethylene Dibromide

1 reference

12 December 2020

Total cytochrome P-450, but not the major phenobarbitone or 3-methylcholanthrene induced isoenzyme, is differentially induced in the lobes of the rat liver

1 reference

12 December 2020

Foreign compound metabolism studies with human liver obtained as surgical waste. Relation to donor characteristics and effects of tissue storage

1 reference

12 December 2020

Interspecies variability in mitoxantrone metabolism using primary cultures of hepatocytes isolated from rat, rabbit and humans

1 reference

12 December 2020

In vivo pharmacokinetics of felodipine predicted from in vitro studies in rat, dog and man

1 reference

12 December 2020

The concentration of cytochrome P-450 in human hepatocyte culture

1 reference

12 December 2020

Prediction of pulmonary benzo(a)pyrene 4,5-oxide clearance: a pharmacokinetic analysis of epoxide-metabolizing enzymes in rabbit lung

1 reference

12 December 2020

Effects of age and gender on in vitro properties of human liver microsomal monooxygenases

1 reference

12 December 2020

Human adult hepatocytes in primary monolayer culture

1 reference

12 December 2020

Preparation of rat liver cells. I. Effect of Ca 2+ on enzymatic dispersion of isolated, perfused liver

1 reference

12 December 2020

Effects of freezing, thawing, and storing human liver microsomes on cytochrome P450 activity.

1 reference

12 December 2020

Prediction of intrinsic clearance of loxtidine from kinetic studies in rat, dog and human hepatocytes

1 reference

12 December 2020

Irreversible binding and metabolism of propranolol by human liver microsomes--relationship to polymorphic oxidation

1 reference

12 December 2020

Liver volume as a determinant of drug clearance in children and adolescents

1 reference

12 December 2020

Distribution of cytochromes P-450, cytochrome b5, and NADPH-cytochrome P-450 reductase in an entire human liver

1 reference

12 December 2020

10.1046/J.1365-2125.2003.01881.X

Identifiers

DOI

1 reference

10 August 2017

1 reference

10 August 2017

PubMed publication ID

12968989

1 reference