Therapeutic targeting of polo-like kinase 1 using RNA-interfering nanoparticles (iNOPs) for the treatment of non-small cell lung cancer (Q35828495)

10 August 2017

Therapeutic targeting of polo-like kinase 1 using RNA-interfering nanoparticles (iNOPs) for the treatment of non-small cell lung cancer (English)

1 reference

10 August 2017

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1

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13 June 2020

Phoebe Phillips

12

1 reference

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13 June 2020

14

Maria Kavallaris

1 reference

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13 June 2020

author name string

Tanya Dwarte

2

1 reference

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13 June 2020

Huricha Baigude

3

1 reference

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13 June 2020

Jason Dang

4

1 reference

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13 June 2020

Lu Yang

5

1 reference

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13 June 2020

Rafael B Erlich

6

1 reference

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13 June 2020

Kathleen Kimpton

7

1 reference

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13 June 2020

Joann Teo

8

1 reference

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13 June 2020

Sharon M Sagnella

9

1 reference

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13 June 2020

Mia C Akerfeldt

10

1 reference

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13 June 2020

Jie Liu

11

1 reference

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13 June 2020

Tariq M Rana

13

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13 June 2020

language of work or name

English

0 references

publication date

1 May 2015

1 reference

10 August 2017

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13 June 2020

volume

6

1 reference

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13 June 2020

issue

14

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13 June 2020

page(s)

12020-12034

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25557168%20AND%20SRC:MED&resulttype=core&format=json

Potential applications of nanotechnology for the diagnosis and treatment of pancreatic cancer

13 June 2020

cites work

1 reference

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In Vivo Delivery of RNAi by Reducible Interfering Nanoparticles (iNOPs).

27 July 2018

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The role of polo-like kinase 1 in carcinogenesis: cause or consequence?

27 July 2018

1 reference

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PDK1 signaling toward PLK1-MYC activation confers oncogenic transformation, tumor-initiating cell activation, and resistance to mTOR-targeted therapy.

27 July 2018

1 reference

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PLK1 signaling in breast cancer cells cooperates with estrogen receptor-dependent gene transcription

27 July 2018

1 reference

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Effective delivery of siRNA into cancer cells and tumors using well-defined biodegradable cationic star polymers

27 July 2018

1 reference

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RNAi-mediated stathmin suppression reduces lung metastasis in an orthotopic neuroblastoma mouse model.

27 July 2018

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First-in-humans trial of an RNA interference therapeutic targeting VEGF and KSP in cancer patients with liver involvement

27 July 2018

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Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010

27 July 2018

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Molecular pathology of non-small cell lung cancer: a practical guide

27 July 2018

1 reference

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Reduced efficacy of the Plk1 inhibitor BI 2536 on the progression of hepatocellular carcinoma due to low intratumoral drug levels

27 July 2018

1 reference

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Polyamidoamine dendrimer nanoparticle cytotoxicity, oxidative stress, caspase activation and inflammatory response: experimental observation and numerical simulation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4494920

Interfering nanoparticles for silencing microRNAs

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4494920

Immunohistochemical detection of Polo-like kinase-1 (PLK1) in primary breast cancer is associated with TP53 mutation and poor clinical outcom

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4494920

High expression of polo-like kinase 1 is associated with the metastasis and recurrence in urothelial carcinoma of bladder

27 July 2018

1 reference

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Overexpression of polo-like kinase 1 and its clinical significance in human non-small cell lung cancer

27 July 2018

1 reference

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Polo-like kinase 1 inhibitors and their potential role in anticancer therapy, with a focus on NSCLC.

27 July 2018

1 reference

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Clinicopathological significance of Polo-like kinase 1 (PLK1) expression in human malignant glioma

27 July 2018

1 reference

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Myricetin induces pancreatic cancer cell death via the induction of apoptosis and inhibition of the phosphatidylinositol 3-kinase (PI3K) signaling pathway

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4494920

Silencing microRNA by interfering nanoparticles in mice

27 July 2018

1 reference

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The Plk1 inhibitor BI 2536 temporarily arrests primary cardiac fibroblasts in mitosis and generates aneuploidy in vitro

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4494920

betaIII-tubulin is a multifunctional protein involved in drug sensitivity and tumorigenesis in non-small cell lung cancer

27 July 2018

1 reference

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Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles

27 July 2018

1 reference

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Microtubules and resistance to tubulin-binding agents

27 July 2018

1 reference

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Overexpression of polo-like kinase1 predicts a poor prognosis in hepatocellular carcinoma patients

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4494920

Delivery of therapeutic RNAi by nanovehicles

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4494920

A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene

27 July 2018

1 reference

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Triptolide induces pancreatic cancer cell death via inhibition of heat shock protein 70.

27 July 2018

1 reference

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Targeted therapy against VEGFR and EGFR with ZD6474 enhances the therapeutic efficacy of irradiation in an orthotopic model of human non-small-cell lung cancer

27 July 2018

1 reference

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BI 2536, a potent and selective inhibitor of polo-like kinase 1, inhibits tumor growth in vivo.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4494920

Illuminating the silence: understanding the structure and function of small RNAs

27 July 2018

1 reference

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Small interfering RNA-mediated Polo-like kinase 1 depletion preferentially reduces the survival of p53-defective, oncogenic transformed cells and inhibits tumor growth in animals

27 July 2018

1 reference

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A novel triple-modality reporter gene for whole-body fluorescent, bioluminescent, and nuclear noninvasive imaging

27 July 2018

1 reference

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Development of an orthotopic model to study the biology and therapy of primary human lung cancer in nude mice.

27 July 2018

1 reference

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Oncogenes in non-small-cell lung cancer: emerging connections and novel therapeutic dynamics

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4494920

Personalizing the treatment of pediatric medulloblastoma: Polo-like kinase 1 as a molecular target in high-risk children

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4494920

Safety and efficacy of RNAi therapy for transthyretin amyloidosis

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4494920

Polo-like kinase 1 inhibition kills glioblastoma multiforme brain tumor cells in part through loss of SOX2 and delays tumor progression in mice.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4494920

Small interfering RNA library screen identified polo-like kinase-1 (PLK1) as a potential therapeutic target for breast cancer that uniquely eliminates tumor-initiating cells

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4494920

Design and creation of new nanomaterials for therapeutic RNAi

24 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25557168

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.18632/ONCOTARGET.2664

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25557168%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25557168%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

PubMed publication ID

25557168

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25557168%20AND%20SRC:MED&resulttype=core&format=json