Adoptive transfer of tumor-primed, in vitro-activated, CD4+ T effector cells (TEs) combined with CD8+ TEs provides intratumoral TE proliferation and synergistic antitumor response (Q35828752)

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scientific article published on 6 February 2007

Language	Label	Description	Also known as
English	Adoptive transfer of tumor-primed, in vitro-activated, CD4+ T effector cells (TEs) combined with CD8+ TEs provides intratumoral TE proliferation and synergistic antitumor response	scientific article published on 6 February 2007

Statements

scholarly article

1 reference

Europe PubMed Central

10 August 2017

Adoptive transfer of tumor-primed, in vitro-activated, CD4+ T effector cells (TEs) combined with CD8+ TEs provides intratumoral TE proliferation and synergistic antitumor response (English)

1 reference

Europe PubMed Central

10 August 2017

author name string

Li-Xin Wang

1

1 reference

Europe PubMed Central

10 August 2017

Suyu Shu

2

1 reference

Europe PubMed Central

10 August 2017

Mary L Disis

3

1 reference

Europe PubMed Central

10 August 2017

Gregory E Plautz

4

1 reference

Europe PubMed Central

10 August 2017

language of work or name

0 references

publication date

6 February 2007

1 reference

Europe PubMed Central

10 August 2017

1 reference

Europe PubMed Central

10 August 2017

109

1 reference

Europe PubMed Central

10 August 2017

11

1 reference

Europe PubMed Central

10 August 2017

4865-4876

1 reference

Europe PubMed Central

10 August 2017

T helper lymphocytes rescue CTL from activation-induced cell death

1 reference

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Adoptive T-cell transfer in cancer immunotherapy

1 reference

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Interleukin-2-dependent mechanisms of tolerance and immunity in vivo

1 reference

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Interleukin-15 rescues tolerant CD8+ T cells for use in adoptive immunotherapy of established tumors

1 reference

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IL-2 administration increases CD4+ CD25(hi) Foxp3+ regulatory T cells in cancer patients

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Rapid assessment of recognition efficiency and functional capacity of antigen-specific T-cell responses.

1 reference

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27 July 2018

Central memory self/tumor-reactive CD8+ T cells confer superior antitumor immunity compared with effector memory T cells

1 reference

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Adoptive T cell therapy of solid cancers

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Adoptive T cell therapy: Addressing challenges in cancer immunotherapy

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Adoptive cell transfer therapy following non-myeloablative but lymphodepleting chemotherapy for the treatment of patients with refractory metastatic melanoma

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CD8+ T cell immunity against a tumor/self-antigen is augmented by CD4+ T helper cells and hindered by naturally occurring T regulatory cells.

1 reference

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Adoptive immunotherapy of cancer with polyclonal, 108-fold hyperexpanded, CD4+ and CD8+ T cells

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Current developments of immunotherapy in the clinic

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IL-15 enhances the in vivo antitumor activity of tumor-reactive CD8+ T cells

1 reference

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Immunotherapy of surgical malignancies

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IL-15Ralpha recycles and presents IL-15 In trans to neighboring cells

1 reference

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Cancer immunoediting: from immunosurveillance to tumor escape

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Enhanced signaling through the IL-2 receptor in CD8+ T cells regulated by antigen recognition results in preferential proliferation and expansion of responding CD8+ T cells rather than promotion of cell death

1 reference

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Contrasting roles of IL-2 and IL-15 in the life and death of lymphocytes: implications for immunotherapy

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CD4+ T cells in adoptive immunotherapy and the indirect mechanism of tumor rejection

1 reference

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Down-regulation of HLA class I antigen-processing molecules in malignant melanoma: association with disease progression

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Ex vivo staining of metastatic lymph nodes by class I major histocompatibility complex tetramers reveals high numbers of antigen-experienced tumor-specific cytolytic T lymphocytes

1 reference

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Loss of HLA class I antigens by melanoma cells: molecular mechanisms, functional significance and clinical relevance

1 reference

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Host lymphodepletion augments T cell adoptive immunotherapy through enhanced intratumoral proliferation of effector cells.

1 reference

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Restoration by IL-15 of MHC class I antigen-processing machinery in human dendritic cells inhibited by tumor-derived gangliosides

1 reference

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Immunotherapy: target the stroma to hit the tumor

1 reference

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Bystander elimination of antigen loss variants in established tumors

1 reference

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Adoptive immunotherapy of advanced tumors with CD62 L-selectin(low) tumor-sensitized T lymphocytes following ex vivo hyperexpansion.

1 reference

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Tumor rejection by disturbing tumor stroma cell interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885514

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Augmentation versus inhibition: effects of conjunctional OX-40 receptor monoclonal antibody and IL-2 treatment on adoptive immunotherapy of advanced tumor

1 reference

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Adoptive tumor therapy with T lymphocytes enriched through an IFN-gamma capture assay.

1 reference

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Progress in human tumour immunology and immunotherapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885514

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CD4+ T cell--mediated tumor rejection involves inhibition of angiogenesis that is dependent on IFN gamma receptor expression by nonhematopoietic cells.

1 reference

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CD4(+) T cells eliminate MHC class II-negative cancer cells in vivo by indirect effects of IFN-gamma

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Treatment of intracranial tumors by systemic transfer of superantigen-activated tumor-draining lymph node T cells.

1 reference

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Isolation based on L-selectin expression of immune effector T cells derived from tumor-draining lymph nodes.

1 reference

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Purification of L-selectin(low) cells promotes the generation of highly potent CD4 antitumor effector T lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17284532

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A live-cell assay to detect antigen-specific CD4+ T cells with diverse cytokine profiles

1 reference

https://pubmed.ncbi.nlm.nih.gov/17284532

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid destruction of the tumor microenvironment by CTLs recognizing cancer-specific antigens cross-presented by stromal cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17284532

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment of subcutaneous tumor with adoptively transferred T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17284532

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specific adoptive immunotherapy mediated by tumor-draining lymph node cells sequentially activated with anti-CD3 and IL-2

1 reference

https://pubmed.ncbi.nlm.nih.gov/17284532

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A new approach to the adoptive immunotherapy of cancer with tumor-infiltrating lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17284532

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cross-presentation of tumor antigens to effector T cells is sufficient to mediate effective immunotherapy of established intracranial tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/17284532

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Therapeutic efficacy of adoptive immunotherapy is predicated on in vivo antigen-specific proliferation of donor T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17284532

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Infiltration of tumors by systemically transferred tumor-reactive T lymphocytes is required for antitumor efficacy

1 reference

https://pubmed.ncbi.nlm.nih.gov/17284532

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lymphopenia and interleukin-2 therapy alter homeostasis of CD4+CD25+ regulatory T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17284532

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cutting edge: CD4 and CD8 T cells are intrinsically different in their proliferative responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/17284532

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sensitive and viable identification of antigen-specific CD8+ T cells by a flow cytometric assay for degranulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17284532

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Generation from tumor-bearing mice of lymphocytes with in vivo therapeutic efficacy

1 reference

https://pubmed.ncbi.nlm.nih.gov/17284532

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1182/BLOOD-2006-09-045245

1 reference

Europe PubMed Central

10 August 2017

1 reference

Europe PubMed Central

10 August 2017

1 reference

Europe PubMed Central

10 August 2017

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