Deregulation of the Rb and p53 pathways in uveal melanoma (Q35829776)

10 August 2017

Deregulation of the Rb and p53 pathways in uveal melanoma (English)

1 reference

10 August 2017

M A Brantley

1

1 reference

PMCID

1885790

10 August 2017

J W Harbour

series ordinal

2

1 reference

PMCID

1885790

10 August 2017

language of work or name

English

0 references

publication date

1 December 2000

1 reference

The American Journal of Pathology

10 August 2017

1 reference

10 August 2017

157

1 reference

10 August 2017

6

1 reference

10 August 2017

1795-1801

1 reference

Inactivation of retinoblastoma protein in uveal melanoma by phosphorylation of sites in the COOH-terminal region.

10 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885790

Rb function in cell-cycle regulation and apoptosis

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885790

Individuals with presumably hereditary uveal melanoma do not harbour germline mutations in the coding regions of either the P16INK4A, P14ARF or cdk4 genes

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885790

11 July 2018

The Hallmarks of Cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885790

Association of specific chromosome alterations with tumour phenotype in posterior uveal melanoma

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885790

Direct induction of cyclin D2 by Myc contributes to cell cycle progression and sequestration of p27.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885790

Cyclins D1 and D2 mediate myc-induced proliferation via sequestration of p27(Kip1) and p21(Cip1).

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885790

BCL-2 family members and the mitochondria in apoptosis

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885790

c-Myc regulates cyclin D-Cdk4 and -Cdk6 activity but affects cell cycle progression at multiple independent points

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885790

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885790

c-myc, p53, and Bcl-2 expression and clinical outcome in uveal melanoma

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885790

Malignant melanoma: modern black plague and genetic black box.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885790

Expression patterns of cyclin D1 and related proteins regulating G1-S phase transition in uveal melanoma and retinoblastoma

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885790

The retinoblastoma protein pathway in cell cycle control and cancer

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885790

Mdm2 promotes the rapid degradation of p53

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885790

p53, the cellular gatekeeper for growth and division

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885790

Bax suppresses tumorigenesis and stimulates apoptosis in vivo

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885790

Constitutional alterations in p16 in patients with uveal melanoma.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885790

Genetic aspects of uveal melanoma: a brief review.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885790

Prognostic parameters in uveal melanoma: a review

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885790

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885790

p53 gene and cell cycling in uveal melanoma

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885790

Clinical implications of the p53 tumor-suppressor gene

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885790

A cell cycle regulator potentially involved in genesis of many tumor types

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885790

Rarity of somatic and germline mutations of the cyclin-dependent kinase 4 inhibitor gene, CDK4I, in melanoma

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885790

TP53 allele loss, mutations and expression in malignant melanoma

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885790

Cytogenetics of twelve cases of uveal melanoma and patterns of nonrandom anomalies and isochromosome formation

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885790

Human retinoblastoma susceptibility gene: cloning, identification, and sequence.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885790

Structural evidence for the authenticity of the human retinoblastoma gene

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885790

A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885790

Abnormalities in structure and expression of the human retinoblastoma gene in SCLC.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885790

C-myc oncogene expression in ocular melanomas

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885790

Increased expression and mutation of p53 in choroidal melanoma

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885790

The prognostic value of cyclin D1, p53, and MDM2 protein expression in uveal melanoma.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885790

The relationship between BcI2, Bax and p53: consequences for cell cycle progression and cell death.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885790

The prognostic significance of c-myc oncogene expression in uveal melanoma.

24 September 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885790

24 September 2018

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2964817-1

Translational enhancement of mdm2 oncogene expression in human tumor cells containing a stabilized wild-type p53 protein.

7 January 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885790

p53-dependent apoptosis suppresses tumor growth and progression in vivo

24 September 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2964817-1

Alcoholic liver disease: I. Interrelationships among histologic features and the histologic effects of prednisolone therapy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2964817-1

Metastatic risk for distinct patterns of postirradiation local recurrence of posterior uveal melanoma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2964817-1

Signaling to p53: breaking the MDM2-p53 circuit

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2964817-1

MDM2 gene amplification and transcript levels in human sarcomas: relationship to TP53 gene status

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2964817-1

Malignant melanoma arising from nevi, p53, p16, and Bcl-2: expression in benign versus malignant components

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2964817-1

Analysis of p16 (CDKN2/MTS-1/INK4A) alterations in primary sporadic uveal melanoma

7 January 2021

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11106551

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Chromosomal gains and losses in uveal melanomas detected by comparative genomic hybridization

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11106551

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Expression of bcl-2 in uveal malignant melanoma

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11106551

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/S0002-9440(10)64817-1

1 reference

10 August 2017

1 reference

10 August 2017

1 reference

PMCID

1885790