4E-BPs Control Fat Storage by Regulating the Expression of Egr1 and ATGL (Q35837163)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25814662%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

title

4E-BPs Control Fat Storage by Regulating the Expression of Egr1 and ATGL (English)

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3 March 2020

6

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3 March 2020

author name string

Maneet Singh

1

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3 March 2020

Yu-Kyong Shin

2

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3 March 2020

Xiaoqing Yang

3

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3 March 2020

Brad Zehr

4

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3 March 2020

Partha Chakrabarti

5

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3 March 2020

language of work or name

English

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publication date

26 March 2015

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Journal of Biological Chemistry

3 March 2020

published in

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3 March 2020

volume

290

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3 March 2020

issue

28

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3 March 2020

page(s)

17331-17338

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The mTORC1/S6K1 pathway regulates glutamine metabolism through the eIF4B-dependent control of c-Myc translation

3 March 2020

cites work

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Insulin inhibits lipolysis in adipocytes via the evolutionarily conserved mTORC1-Egr1-ATGL-mediated pathway

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27 July 2018

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27 July 2018

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27 July 2018

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Mammalian target of rapamycin complex 1 suppresses lipolysis, stimulates lipogenesis, and promotes fat storage

27 July 2018

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27 July 2018

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27 July 2018

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Contribution of adipose triglyceride lipase and hormone-sensitive lipase to lipolysis in hMADS adipocytes

27 July 2018

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The transcription factors Egr1 and Egr2 have opposing influences on adipocyte differentiation.

27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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The adipose tissue triglyceride lipase ATGL/PNPLA2 is downregulated by insulin and TNF-alpha in 3T3-L1 adipocytes and is a target for transactivation by PPARgamma

27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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Desnutrin, an adipocyte gene encoding a novel patatin domain-containing protein, is induced by fasting and glucocorticoids: ectopic expression of desnutrin increases triglyceride hydrolysis.

27 July 2018

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27 July 2018

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27 July 2018

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Expression Profiling Identifies Genes That Continue to Respond to Insulin in Adipocytes Made Insulin-resistant by Treatment with Tumor Necrosis Factor-α

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498071

Regulation of life and death by the zinc finger transcription factor Egr-1.

27 July 2018

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Amino acid and insulin signaling via the mTOR/p70 S6 kinase pathway. A negative feedback mechanism leading to insulin resistance in skeletal muscle cells

27 July 2018

1 reference

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Signaling pathways leading to transcription and translation cooperatively regulate the transient increase in expression of c-Fos protein

27 July 2018

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Regulation of translation initiation by FRAP/mTOR

27 July 2018

1 reference

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Identification of two polymorphisms in the early growth response protein-1 gene: possible association with lipid variables

27 July 2018

1 reference

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Translational induction of the c-myc oncogene via activation of the FRAP/TOR signalling pathway

27 July 2018

1 reference

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Models of insulin action on metabolic and growth response genes

27 July 2018

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RNA G-quadruplexes cause eIF4A-dependent oncogene translation in cancer

27 July 2018

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Signal integration by mTORC1 coordinates nutrient input with biosynthetic output.

24 September 2018

1 reference

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Regulation of mTORC1 and its impact on gene expression at a glance

24 September 2018

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Critical role of Egr transcription factors in regulating insulin biosynthesis, blood glucose homeostasis, and islet size

24 September 2018

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Early growth response 1 (Egr1) regulates cholesterol biosynthetic gene expression

24 September 2018

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Phosphoproteomic analysis identifies Grb10 as an mTORC1 substrate that negatively regulates insulin signaling

24 September 2018

1 reference

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The mTOR-regulated phosphoproteome reveals a mechanism of mTORC1-mediated inhibition of growth factor signaling.

24 September 2018

1 reference

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Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498071

Activated FOXO-mediated insulin resistance is blocked by reduction of TOR activity.

24 September 2018

1 reference

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Critical nodes in signalling pathways: insights into insulin action

24 September 2018

1 reference

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Nutrients suppress phosphatidylinositol 3-kinase/Akt signaling via raptor-dependent mTOR-mediated insulin receptor substrate 1 phosphorylation

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498071

Brummer lipase is an evolutionary conserved fat storage regulator in Drosophila

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498071

Banting lecture 2001: dysregulation of fatty acid metabolism in the etiology of type 2 diabetes

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498071

24 September 2018

Identifiers

DOI

10.1074/JBC.M114.631895

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25814662%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25814662%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

PubMed publication ID

25814662

1 reference