Cardiac and vascular phenotypes in the apolipoprotein E-deficient mouse. (Q35837289)

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Cardiac and vascular phenotypes in the apolipoprotein E-deficient mouse (English)

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familial dysbetalipoproteinemia

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Veronica A Peotta

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Agata L Gava

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Thiago Mc Pereira

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Silvana S Meyrelles

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Journal of Biomedical Science

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cites work

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Angiotensin type 1 receptor blocker reduces intimal neovascularization and plaque growth in apolipoprotein E-deficient mice

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Protective effects of PARP-1 knockout on dyslipidemia-induced autonomic and vascular dysfunction in ApoE mice: effects on eNOS and oxidative stress

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N-acetylcysteine reduces the severity of atherosclerosis in apolipoprotein E-deficient mice by reducing superoxide production

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Paraoxonase 1 gene transfer lowers vascular oxidative stress and improves vasomotor function in apolipoprotein E-deficient mice with pre-existing atherosclerosis.

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Overview of murine atherosclerosis series

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Subendothelial lipoprotein retention as the initiating process in atherosclerosis: update and therapeutic implications

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A mouse model for human atherosclerosis: long-term histopathological study of lesion development in the aortic arch of apolipoprotein E-deficient (E0) mice

11 July 2018

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Inflammation and atherosclerosis: novel insights into plaque formation and destabilization

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The impact of progenitor cells in atherosclerosis

11 July 2018

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Atherogenesis in perspective: hypercholesterolemia and inflammation as partners in crime

11 July 2018

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Elevated levels of oxidative DNA damage and DNA repair enzymes in human atherosclerotic plaques

11 July 2018

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11 July 2018

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The hypertension-lipid connection: insights into the relation between angiotensin II and cholesterol in atherogenesis

11 July 2018

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eNOS activity is reduced in senescent human endothelial cells: Preservation by hTERT immortalization

11 July 2018

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Antagonism of AT2 receptors augments angiotensin II-induced abdominal aortic aneurysms and atherosclerosis

11 July 2018

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Endothelial regulation of vasomotion in apoE-deficient mice: implications for interactions between peroxynitrite and tetrahydrobiopterin

11 July 2018

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Angiotensin II-induced hypertension accelerates the development of atherosclerosis in apoE-deficient mice

11 July 2018

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Angiotensin II promotes atherosclerotic lesions and aneurysms in apolipoprotein E-deficient mice

11 July 2018

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Increased aortic stiffness assessed by pulse wave velocity in apolipoprotein E-deficient mice

11 July 2018

1 reference

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Hypertension and endothelial dysfunction in apolipoprotein E knockout mice

11 July 2018

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Endothelin ETA receptor blockade restores NO-mediated endothelial function and inhibits atherosclerosis in apolipoprotein E-deficient mice

11 July 2018

1 reference

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Estrogen reduces atherosclerotic lesion development in apolipoprotein E-deficient mice

11 July 2018

1 reference

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The pathogenesis of atherosclerosis: a perspective for the 1990s

11 July 2018

1 reference

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Diet-induced atherosclerosis in mice heterozygous and homozygous for apolipoprotein E gene disruption

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3306747

Generation of mice carrying a mutant apolipoprotein E gene inactivated by gene targeting in embryonic stem cells

11 July 2018

1 reference

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Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells

11 July 2018

1 reference

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Vasoprotective and atheroprotective effects of angiotensin (1-7) in apolipoprotein E-deficient mice.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3306747

Cardiac fibrosis and diastolic dysfunction after myocardial infarction in apolipoprotein E knockout mice

24 September 2018

1 reference

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A novel 3-dimensional micro-ultrasound approach to automated measurement of carotid arterial plaque volume as a biomarker for experimental atherosclerosis.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3306747

Heart rate reduction by ivabradine reduces oxidative stress, improves endothelial function, and prevents atherosclerosis in apolipoprotein E-deficient mice

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3306747

PARP1 is required for adhesion molecule expression in atherogenesis

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3306747

Chronic angiotensin IV treatment reverses endothelial dysfunction in ApoE-deficient mice

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3306747

Evaluation of aortic remodeling in apolipoprotein E-deficient mice and renovascular hypertensive mice.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3306747

Evaluation of baroreflex control of heart rate in renovascular hypertensive mice.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3306747

Altered mechanisms of endothelium-dependent dilation in skeletal muscle arterioles with genetic hypercholesterolemia.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3306747

Reduced cardiac functional reserve in apolipoprotein E knockout mice

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3306747

Evaluation of vascular function in apolipoprotein E knockout mice with angiotensin-dependent renovascular hypertension.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3306747

Differential effects of angiotensin II on atherogenesis at the aortic sinus and descending aorta of apolipoprotein-E-deficient mice

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3306747

Haemodynamically significant plaque formation and regional endothelial dysfunction in cholesterol-fed ApoE-/- mice

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3306747

Inhibition of diet-induced atherosclerosis and endothelial dysfunction in apolipoprotein E/angiotensin II type 1A receptor double-knockout mice

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3306747

Restoration of the endothelial function in the aortic rings of apolipoprotein E deficient mice by pharmacological inhibition of the nuclear enzyme poly(ADP-ribose) polymerase

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3306747

Plaque-associated endothelial dysfunction in apolipoprotein E-deficient mice on a regular diet. Effect of human apolipoprotein AI.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3306747

Rosuvastatin decreases caveolin-1 and improves nitric oxide-dependent heart rate and blood pressure variability in apolipoprotein E-/- mice in vivo.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3306747

Fluvastatin prevents renal dysfunction and vascular NO deficit in apolipoprotein E-deficient mice.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3306747

Activation of poly(ADP-ribose) polymerase contributes to the endothelial dysfunction associated with hypertension and aging.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3306747

Loss of SR-BI expression leads to the early onset of occlusive atherosclerotic coronary artery disease, spontaneous myocardial infarctions, severe cardiac dysfunction, and premature death in apolipoprotein E-deficient mice

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3306747

Chronic ET(A) receptor blockade prevents endothelial dysfunction of small arteries in apolipoprotein E-deficient mice

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3306747

Spontaneous plaque rupture and secondary thrombosis in apolipoprotein E-deficient and LDL receptor-deficient mice

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3306747

Endothelial dysfunction induced by oxidized low-density lipoproteins in isolated mouse aorta: a comparison with apolipoprotein-E deficient mice

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3306747

Mechanism of endothelial dysfunction in apolipoprotein E-deficient mice.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3306747

Impairment of endothelium-dependent arterial relaxation by high-fat feeding in ApoE-deficient mice: toward normalization by human ApoA-I expression

24 September 2018

1 reference

12 December 2020

Cerebral vascular dysfunction during hypercholesterolemia

1 reference

12 December 2020

Hypercholesterolemia stimulates angiotensin peptide synthesis and contributes to atherosclerosis through the AT1A receptor

1 reference

12 December 2020

ApoE-deficient mice develop lesions of all phases of atherosclerosis throughout the arterial tree

1 reference

12 December 2020

Interleukin-1 receptor type-1 in non-hematopoietic cells is the target for the pro-atherogenic effects of interleukin-1 in apoE-deficient mice

1 reference

12 December 2020

New insights into immunological aspects of atherosclerosis

1 reference

12 December 2020

Characterization of epitopes recognized by 4-hydroxy-2-nonenal specific antibodies

1 reference

12 December 2020

Aortic constriction exacerbates atherosclerosis and induces cardiac dysfunction in mice lacking apolipoprotein E

1 reference

12 December 2020

Rapid restoration of normal endothelial functions in genetically hyperlipidemic mice by a synthetic mediator of reverse lipid transport

1 reference

12 December 2020

In vivo echocardiographic detection of cardiovascular lesions in apolipoprotein E-knockout mice using a novel high-frequency high-speed echocardiography technique

1 reference

12 December 2020

Transfer of CD4(+) T cells aggravates atherosclerosis in immunodeficient apolipoprotein E knockout mice

1 reference

12 December 2020

Transiently heightened angiotensin II has distinct effects on atherosclerosis and aneurysm formation in hyperlipidemic mice

1 reference

12 December 2020

Atherosclerosis, vascular remodeling, and impairment of endothelium-dependent relaxation in genetically altered hyperlipidemic mice

1 reference

12 December 2020

Accelerated atherosclerosis, aortic aneurysm formation, and ischemic heart disease in apolipoprotein E/endothelial nitric oxide synthase double-knockout mice

1 reference

12 December 2020

Peripheral vascular stenosis in apolipoprotein E-deficient mice. Potential roles of lipid deposition, medial atrophy, and adventitial inflammation

1 reference

12 December 2020

Expansive remodeling is a response of the plaque-related vessel wall in aortic roots of apoE-deficient mice: an experiment of nature

1 reference

12 December 2020

Hemodynamic changes in apolipoprotein E-knockout mice

1 reference

12 December 2020

Improvement of endothelial function by systemic transfusion of vascular progenitor cells

1 reference

12 December 2020

Decreased sensitivity to nitric oxide in the aorta of severely hypercholesterolemic apolipoprotein E-deficient mice

1 reference

12 December 2020

Identifiers

DOI

10.1186/1423-0127-19-22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22330242%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

22 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22330242%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

PubMed publication ID

22330242

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22330242%20AND%20SRC:MED&resulttype=core&format=json