Generation of mice carrying a mutant apolipoprotein E gene inactivated by gene targeting in embryonic stem cells (Q37011453)

17 August 2017

Generation of mice carrying a mutant apolipoprotein E gene inactivated by gene targeting in embryonic stem cells (English)

1 reference

17 August 2017

1 reference

genetic recombination

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1584779

11 October 2022

author name string

J. A. Piedrahita

1

1 reference

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11 October 2022

S. H. Zhang

2

1 reference

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11 October 2022

J. R. Hagaman

3

1 reference

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11 October 2022

P. M. Oliver

4

1 reference

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11 October 2022

N. Maeda

5

1 reference

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11 October 2022

language of work or name

English

0 references

publication date

1 May 1992

1 reference

PMCID

49104

17 August 2017

15 May 1992

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=1584779

full work available at URL

11 October 2022

https://europepmc.org/articles/PMC49104

1 reference

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https://europepmc.org/articles/PMC49104?pdf=render

11 October 2022

file format

Portable Document Format

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1584779

Proceedings of the National Academy of Sciences of the United States of America

11 October 2022

published in

1 reference

17 August 2017

89

1 reference

17 August 2017

4471-4475

1 reference

17 August 2017

10

1 reference

Diffusion-in-gel methods for immunological analysis. II

17 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49104

Type III hyperlipoproteinemia: recent insights into the genetic defect of familial dysbetalipoproteinemia

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49104

Genetics of coronary heart disease.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49104

Inherited resistance to N- and B-tropic murine leukemia viruses in vitro: evidence that congenic mouse strains SIM and SIM.R differ at the Fv-1 locus

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49104

The in vitro development of blastocyst-derived embryonic stem cell lines: formation of visceral yolk sac, blood islands and myocardium

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49104

Evolution of apolipoprotein E: mouse sequence and evidence for an 11-nucleotide ancestral unit

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49104

HPRT-deficient (Lesch-Nyhan) mouse embryos derived from germline colonization by cultured cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49104

Ath-1, a gene determining atherosclerosis susceptibility and high density lipoprotein levels in mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49104

A simple salting out procedure for extracting DNA from human nucleated cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49104

Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49104

Recombinant fragment assay for gene targetting based on the polymerase chain reaction

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49104

Apolipoprotein genetic variation and human disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49104

Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49104

The new mouse genetics: altering the genome by gene targeting

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49104

Germ-line transmission of a planned alteration made in a hypoxanthine phosphoribosyltransferase gene by homologous recombination in embryonic stem cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49104

Structure and expression of mouse apolipoprotein E gene

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49104

A role for apolipoprotein E, apolipoprotein A-I, and low density lipoprotein receptors in cholesterol transport during regeneration and remyelination of the rat sciatic nerve

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49104

Targeted disruption of the murine int-1 proto-oncogene resulting in severe abnormalities in midbrain and cerebellar development

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49104

Target frequency and integration pattern for insertion and replacement vectors in embryonic stem cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49104

Cotransformation and gene targeting in mouse embryonic stem cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49104

Lambda Charon vectors (Ch32, 33, 34 and 35) adapted for DNA cloning in recombination-deficient hosts

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49104

The molecular basis of a familial apoE deficiency. An acceptor splice site mutation in the third intron of the deficient apoE gene

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49104

Expression of apolipoprotein E by cultured vascular smooth muscle cells is controlled by growth state

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49104

Normal development of mice deficient in beta 2M, MHC class I proteins, and CD8+ T cells.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49104

Apolipoprotein E deficiency with a depressed mRNA of normal size.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49104

Characterization of the sinusoidal transport process responsible for uptake of chylomicrons by the liver

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49104

The molecular basis of atherosclerosis: concepts derived from studies of lipoprotein metabolism and cell biology

27 June 2018

1 reference

12 December 2020

In vitro expression of a 38,000 dalton heparin-binding glycoprotein by morphologically differentiated smooth muscle cells

1 reference

12 December 2020

A young type III hyperlipoproteinemic patient associated with apolipoprotein E deficiency

1 reference

12 December 2020

Lipoprotein binding to canine hepatic membranes. Metabolically distinct apo-E and apo-B,E receptors

1 reference

12 December 2020

Distribution and characterization of the serum lipoproteins and apoproteins in the mouse, Mus musculus

1 reference

12 December 2020

Type III hyperlipoproteinemia associated with apolipoprotein E deficiency

1 reference

12 December 2020

Immunoregulatory plasma lipoproteins. Role of apoprotein E and apoprotein B

1 reference

12 December 2020

Heterogeneity of human plasma very low density lipoproteins. Separation of species differing in protein components

1 reference

12 December 2020

Extrahepatic synthesis of apolipoprotein E

1 reference

12 December 2020

Regulation of apolipoprotein E gene expression after injury of the rat sciatic nerve

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.89.10.4471

1 reference

17 August 2017

0 references

1 reference

17 August 2017

1 reference

PMCID

49104