Immunotherapy of high-risk acute leukemia with a recipient (autologous) vaccine expressing transgenic human CD40L and IL-2 after chemotherapy and allogeneic stem cell transplantation. (Q35848688)

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scientific article published on 25 October 2005

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English	Immunotherapy of high-risk acute leukemia with a recipient (autologous) vaccine expressing transgenic human CD40L and IL-2 after chemotherapy and allogeneic stem cell transplantation.	scientific article published on 25 October 2005

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8 January 2020

Immunotherapy of high-risk acute leukemia with a recipient (autologous) vaccine expressing transgenic human CD40L and IL-2 after chemotherapy and allogeneic stem cell transplantation (English)

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Michael P. Brown

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Malcolm Brenner

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Malcolm K Brenner

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Helen E Heslop

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Adrian P Gee

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Robert A Krance

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Robert A Krance

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George Carrum

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Zhuyong Mei

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Bambi Jo Grilley

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Bambi Grilley

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Eric S Yvon

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Ettore Biagi

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Uday Popat

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Aurélie Dutour

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Aurélie Dutour

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Judith F Margolin

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Judith F Margolin

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Raphaël F Rousseau

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Tiffany Lin

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Edwina Popek

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25 October 2005

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1332-1341

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4

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8 January 2020

Antigen-specific T-cell memory is preserved in children treated for acute lymphoblastic leukemia

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11 July 2018

Dendritic cell regulation of immune responses: a new role for interleukin 2 at the intersection of innate and adaptive immunity

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Bystander Transfer of Functional Human CD40 Ligand from Gene-Modified Fibroblasts to B-Chronic Lymphocytic Leukemia Cells

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Local and systemic effects of an allogeneic tumor cell vaccine combining transgenic human lymphotactin with interleukin-2 in patients with advanced or refractory neuroblastoma

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Immunotherapy with acute leukemia cells modified into antigen-presenting cells: ex vivo culture and gene transfer methods

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Tumor-induced death of immune cells: its mechanisms and consequences

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Effectiveness of donor natural killer cell alloreactivity in mismatched hematopoietic transplants

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Hematopoietic system-specific antigens as targets for cellular immunotherapy of hematological malignancies

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11 July 2018

Chemoattractants MDC and TARC are secreted by malignant B-cell precursors following CD40 ligation and support the migration of leukemia-specific T cells

1 reference

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11 July 2018

Efficient lentiviral transduction of primary human acute myelogenous and lymphoblastic leukemia cells

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11 July 2018

CD40-ligand (CD154) gene therapy for chronic lymphocytic leukemia

1 reference

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11 July 2018

Generation of tumor-specific T-lymphocytes by cross-priming with human dendritic cells ingesting apoptotic tumor cells

1 reference

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11 July 2018

CD40-CD40 ligand interactions in vivo regulate migration of antigen-bearing dendritic cells from the skin to draining lymph nodes

1 reference

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The central role of CD4(+) T cells in the antitumor immune response

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11 July 2018

CD40-activated human B cells: an alternative source of highly efficient antigen presenting cells to generate autologous antigen-specific T cells for adoptive immunotherapy

1 reference

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11 July 2018

The role of B7 costimulation by murine acute myeloid leukemia in the generation and function of a CD8+ T-cell line with potent in vivo graft-versus-leukemia properties.

1 reference

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Lymphocyte responses and cytokines

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11 July 2018

IL-2 inhibits proliferation of K562 cells and reduces accumulation of bcr/abl mRNA and oncoprotein

1 reference

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11 July 2018

Priming of tumor-specific T cells in the draining lymph nodes after immunization with interleukin 2-secreting tumor cells: three consecutive stages may be required for successful tumor vaccination

1 reference

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11 July 2018

Activated T cells induce expression of B7/BB1 on normal or leukemic B cells through a CD40-dependent signal

1 reference

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11 July 2018

Human CD40-ligand: molecular cloning, cellular distribution and regulation of expression by factors controlling IgE production

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11 July 2018

Follicular lymphomas can be induced to present alloantigen efficiently: a conceptual model to improve their tumor immunogenicity

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11 July 2018

Role of B7-1 in mediating an immune response to myeloid leukemia cells.

1 reference

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11 July 2018

Activation of human dendritic cells through CD40 cross-linking.

1 reference

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11 July 2018

CD40L: a multi-functional ligand

1 reference

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11 July 2018

Interleukin 2 does not promote the in vitro and in vivo proliferation and growth of human acute leukaemia cells of myeloid and lymphoid origin

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11 July 2018

The distinct surface of human blood dendritic cells, as observed after an improved isolation method

1 reference

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11 July 2018

Interleukin-2 production by tumor cells bypasses T helper function in the generation of an antitumor response

1 reference

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Evidence for somatic selection of natural autoantibodies

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Costimulation of T lymphocytes: the role of CD28, CTLA-4, and B7/BB1 in interleukin-2 production and immunotherapy

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Human primary and memory cytotoxic T lymphocyte responses are efficiently induced by means of CD40-activated B cells as antigen-presenting cells: potential for clinical application

1 reference

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24 September 2018

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1 reference

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24 September 2018

Autologous antileukemic immune response induced by chronic lymphocytic leukemia B cells expressing the CD40 ligand and interleukin 2 transgenes

1 reference

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24 September 2018

Proinflammatory cytokines and CD40 ligand enhance cross-presentation and cross-priming capability of human dendritic cells internalizing apoptotic cancer cells

1 reference

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24 September 2018

T-cell help for cytotoxic T lymphocytes is mediated by CD40-CD40L interactions.

1 reference

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24 September 2018

CD40 ligand induces an antileukemia immune response in vivo.

1 reference

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24 September 2018

A new mechanism of NK cell cytotoxicity activation: the CD40-CD40 ligand interaction.

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1 reference

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24 September 2018

Irradiated B7-1 transduced primary acute myelogenous leukemia (AML) cells can be used as therapeutic vaccines in murine AML

1 reference

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22 October 2018

Pre-B acute lymphoblastic leukemia cells may induce T-cell anergy to alloantigen

1 reference

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22 October 2018

CD40 activation in vivo overcomes peptide-induced peripheral cytotoxic T-lymphocyte tolerance and augments anti-tumor vaccine efficacy

1 reference

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6 December 2018

IL-2 adenovector-transduced autologous tumor cells induce antitumor immune responses in patients with neuroblastoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/16249392

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD40 antibody evokes a cytotoxic T-cell response that eradicates lymphoma and bypasses T-cell help

1 reference

https://pubmed.ncbi.nlm.nih.gov/16249392

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A PR1-human leukocyte antigen-A2 tetramer can be used to isolate low-frequency cytotoxic T lymphocytes from healthy donors that selectively lyse chronic myelogenous leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/16249392

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autoimmune disease induced by dendritic cell immunization against leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/16249392

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Conversion of tumor-specific CD4+ T-cell tolerance to T-cell priming through in vivo ligation of CD40

1 reference

https://pubmed.ncbi.nlm.nih.gov/16249392

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Failure to define window of time for autologous tumor vaccination in patients with newly diagnosed or relapsed acute lymphoblastic leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/16249392

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo antitumor effect of CD40L-transduced tumor cells as a vaccine for B-cell lymphoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/16249392

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD40 ligand-stimulated B cell precursor leukemic cells elicit interferon-gamma production by autologous bone marrow T cells in childhood acute lymphoblastic leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/16249392

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of interleukin-2 receptor beta subunit in hematopoietic malignancies

1 reference

https://pubmed.ncbi.nlm.nih.gov/16249392

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High and low affinity IL-2 receptors on human leukaemic blast cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16249392

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Susceptibility of human leukemia to allogeneic and autologous lymphokine-activated killer cell activity: analysis of 252 samples

1 reference

https://pubmed.ncbi.nlm.nih.gov/16249392

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD40 ligand is a T cell growth factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/16249392

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of CD40 antigen and interleukin-2 in T cell-dependent human B lymphocyte growth

1 reference

https://pubmed.ncbi.nlm.nih.gov/16249392

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD40 preferentially costimulates activation of CD4+ T lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/16249392

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recombinant CD40 ligand exerts potent biologic effects on T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16249392

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transduction of the IL2 gene into human acute leukemia cells: induction of tumor rejection without modifying cell proliferation and IL2 receptor expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/16249392

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of the CD40-CD40 ligand interaction in CD4+ T cell contact-dependent activation of monocyte interleukin-1 synthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16249392

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence that specific T lymphocytes may participate in the elimination of chronic myelogenous leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/16249392

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Demonstration of functional CD40 in B-lineage acute lymphoblastic leukemia cells in response to T-cell CD40 ligand

1 reference

https://pubmed.ncbi.nlm.nih.gov/16249392

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ex vivo generation of human anti-pre-B leukemia-specific autologous cytolytic T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16249392

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1182/BLOOD-2005-03-1259

1 reference

Europe PubMed Central

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8 January 2020

1 reference

Europe PubMed Central

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8 January 2020

1 reference

Europe PubMed Central

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8 January 2020

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