Physiological roles of amyloid-beta and implications for its removal in Alzheimer's disease (Q35852763)

10 August 2017

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title

Physiological roles of amyloid-beta and implications for its removal in Alzheimer's disease (English)

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10 August 2017

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Glenda M Bishop

1

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PubMed ID

15287821

10 August 2017

Stephen R Robinson

series ordinal

2

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10 August 2017

1 January 2004

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10 August 2017

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10 August 2017

21

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10 August 2017

621-630

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10 August 2017

10

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https://scigraph.springernature.com/pub.10.2165/00002512-200421100-00001

10 August 2017

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cites work

Binding of Zn(II), Cu(II), and Fe(II) ions to Alzheimer's A beta peptide studied by fluorescence

1 reference

12 December 2020

The production of amyloid beta peptide is a critical requirement for the viability of central neurons.

1 reference

12 December 2020

Serum amyloid P component binds to influenza A virus haemagglutinin and inhibits the virus infection in vitro.

1 reference

12 December 2020

Deposits of A beta fibrils are not toxic to cortical and hippocampal neurons in vitro

1 reference

12 December 2020

The amyloid hypothesis: let sleeping dogmas lie?

1 reference

12 December 2020

Mechanisms contributing to the deficits in hippocampal synaptic plasticity in mice lacking amyloid precursor protein

1 reference

12 December 2020

Abeta as a bioflocculant: implications for the amyloid hypothesis of Alzheimer's disease.

1 reference

12 December 2020

Deficient neurogenesis in forebrain-specific presenilin-1 knockout mice is associated with reduced clearance of hippocampal memory traces

1 reference

12 December 2020

Amyloid beta binding proteins in vitro and in normal human cerebrospinal fluid

1 reference

12 December 2020

Patients with Alzheimer disease have lower levels of serum anti-amyloid peptide antibodies than healthy elderly individuals

1 reference

12 December 2020

Neuronal deficiency of presenilin 1 inhibits amyloid plaque formation and corrects hippocampal long-term potentiation but not a cognitive defect of amyloid precursor protein [V717I] transgenic mice.

1 reference

12 December 2020

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

1 reference

12 December 2020

Autoantibodies to amyloid beta-peptide (Abeta) are increased in Alzheimer's disease patients and Abeta antibodies can enhance Abeta neurotoxicity: implications for disease pathogenesis and vaccine development

1 reference

12 December 2020

1 reference

12 December 2020

Resistance of human cerebrospinal fluid to in vitro oxidation is directly related to its amyloid-beta content

1 reference

12 December 2020

Serum amyloid P component bound to gram-negative bacteria prevents lipopolysaccharide-mediated classical pathway complement activation

1 reference

12 December 2020

A novel function of monomeric amyloid beta-protein serving as an antioxidant molecule against metal-induced oxidative damage

1 reference

12 December 2020

beta-Amyloid-(1-40) increases long-term potentiation in rat hippocampus in vitro

1 reference

12 December 2020

Clearance of Alzheimer's amyloid-ss(1-40) peptide from brain by LDL receptor-related protein-1 at the blood-brain barrier

1 reference

12 December 2020

Lessons from the AN 1792 Alzheimer vaccine: lest we forget.

1 reference

12 December 2020

Nerve inflammation halts trial for Alzheimer's drug.

1 reference

12 December 2020

Use-dependent effects of amyloidogenic fragments of (beta)-amyloid precursor protein on synaptic plasticity in rat hippocampus in vivo.

1 reference

12 December 2020

Immunization with a nontoxic/nonfibrillar amyloid-beta homologous peptide reduces Alzheimer's disease-associated pathology in transgenic mice

1 reference

12 December 2020

Amyloid beta-peptide (1-42)-induced oxidative stress and neurotoxicity: implications for neurodegeneration in Alzheimer's disease brain. A review

1 reference

12 December 2020

Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis

1 reference

12 December 2020

Combination assay of CSF tau, A beta 1-40 and A beta 1-42(43) as a biochemical marker of Alzheimer's disease.

1 reference

12 December 2020

Copper, iron and zinc in Alzheimer's disease senile plaques.

1 reference

12 December 2020

BACE1 deficiency rescues memory deficits and cholinergic dysfunction in a mouse model of Alzheimer's disease

1 reference

12 December 2020

Oxidative damage is the earliest event in Alzheimer disease

1 reference

12 December 2020

Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease

1 reference

12 December 2020

Alzheimer vaccine: amyloid-beta on trial.

1 reference

12 December 2020

Impairments of long-term potentiation in hippocampal slices of beta-amyloid-infused rats.

1 reference

12 December 2020

Beta-amyloid regulation of presynaptic nicotinic receptors in rat hippocampus and neocortex.

1 reference

12 December 2020

Astrocytes: glutamate producers for neurons

1 reference

12 December 2020

Amyloid beta protein in plasma from patients with sporadic Alzheimer's disease.

1 reference

12 December 2020

Aluminum promotes the aggregation of Alzheimer's amyloid beta-protein in vitro

1 reference

12 December 2020

Generation of antibodies specific for beta-amyloid by vaccination of patients with Alzheimer disease.

1 reference

12 December 2020

Amyloid precursor protein and membrane phospholipids in primary cortical neurons increase with development, or after exposure to nerve growth factor or Abeta(1-40)

1 reference

12 December 2020

Potential neurotoxic inflammatory responses to Abeta vaccination in humans.

1 reference

12 December 2020

Dramatic aggregation of Alzheimer abeta by Cu(II) is induced by conditions representing physiological acidosis.

1 reference

12 December 2020

Identification and localization of Chlamydia pneumoniae in the Alzheimer's brain

1 reference

12 December 2020

NMDA receptor regulation by amyloid-beta does not account for its inhibition of LTP in rat hippocampus

1 reference

12 December 2020

Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides

1 reference

12 December 2020

The effects of age, apolipoprotein E phenotype and gender on the concentration of amyloid-beta (A beta) 40, A beta 4242, apolipoprotein E and transthyretin in human cerebrospinal fluid.

1 reference

12 December 2020

Reduced levels of amyloid beta-peptide antibody in Alzheimer disease

1 reference

12 December 2020

Involvement of amyloid precursor protein in memory formation in the rat: an indirect antibody approach.

1 reference

12 December 2020

BACE1 (beta-secretase) knockout mice do not acquire compensatory gene expression changes or develop neural lesions over time

1 reference

12 December 2020

Alzheimer's disease-affected brain: presence of oligomeric A beta ligands (ADDLs) suggests a molecular basis for reversible memory loss

1 reference

12 December 2020

APP processing and synaptic plasticity in presenilin-1 conditional knockout mice

1 reference

12 December 2020

Amyloid beta protein enhances the survival of hippocampal neurons in vitro

1 reference

12 December 2020

Glutamine synthetase, hemoglobin alpha-chain, and macrophage migration inhibitory factor binding to amyloid beta-protein: their identification in rat brain by a novel affinity chromatography and in Alzheimer's disease brain by immunoprecipitation

1 reference

12 December 2020

APP is required during an early phase of memory formation.

1 reference

12 December 2020

Impairment in hippocampal long-term potentiation in mice under-expressing the Alzheimer's disease related gene presenilin-1

1 reference

12 December 2020

The levels of cerebrospinal fluid Abeta40 and Abeta42(43) are regulated age-dependently.

1 reference

12 December 2020

Amyloid-beta is an antioxidant for lipoproteins in cerebrospinal fluid and plasma

1 reference

12 December 2020

Plasma A[beta]40 and A[beta]42 and Alzheimer's disease: relation to age, mortality, and risk

1 reference

12 December 2020

Human Abeta1-42 reduces iron-induced toxicity in rat cerebral cortex

1 reference

12 December 2020

New insights into the role of serum amyloid P component, a novel lipopolysaccharide-binding protein

1 reference

12 December 2020

Turnover of amyloid beta-protein in mouse brain and acute reduction of its level by phorbol ester.

1 reference

12 December 2020

Antibodies to beta-amyloid decrease the blood-to-brain transfer of beta-amyloid peptide.

1 reference

12 December 2020

What the evolution of the amyloid protein precursor supergene family tells us about its function

1 reference

12 December 2020

Regenerative failure: a potential mechanism for neuritic dystrophy in Alzheimer's disease.

1 reference

12 December 2020

Administration of aggregated beta-amyloid peptide (25-35) induces changes in long-term potentiation in the hippocampus in vivo.

1 reference

12 December 2020

Autoantibodies to amyloid-beta and Alzheimer's disease.

1 reference

12 December 2020

APP processing and synaptic function

1 reference

12 December 2020

Secretion of Alzheimer's disease Abeta amyloid peptide by activated human platelets

1 reference

12 December 2020

Human blood-brain barrier receptors for Alzheimer's amyloid-beta 1- 40. Asymmetrical binding, endocytosis, and transcytosis at the apical side of brain microvascular endothelial cell monolayer

1 reference

12 December 2020

Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse

1 reference

12 December 2020

BACE1 is the major beta-secretase for generation of Abeta peptides by neurons

1 reference

12 December 2020

Beta-amyloid enhances glial glutamate uptake activity and attenuates synaptic efficacy.

1 reference

12 December 2020

The molecular pathology of Alzheimer's disease

1 reference

12 December 2020

Plasma amyloid beta-peptide 1-42 and incipient Alzheimer's disease

1 reference

12 December 2020

Amyloid peptide Abeta(1-42) binds selectively and with picomolar affinity to alpha7 nicotinic acetylcholine receptors

1 reference

12 December 2020

Amyloid-beta immunotherapy for Alzheimer's disease: the end of the beginning

1 reference

12 December 2020

Increased T cell reactivity to amyloid beta protein in older humans and patients with Alzheimer disease

1 reference

12 December 2020

Analysis of heterogeneous A4 peptides in human cerebrospinal fluid and blood by a newly developed sensitive Western blot assay.

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12 December 2020

RAGE mediates amyloid-beta peptide transport across the blood-brain barrier and accumulation in brain

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12 December 2020

Amyloid beta-peptide induces apoptosis-related events in synapses and dendrites.

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12 December 2020

BACE knockout mice are healthy despite lacking the primary beta-secretase activity in brain: implications for Alzheimer's disease therapeutics

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12 December 2020

Aluminum, iron, and zinc ions promote aggregation of physiological concentrations of beta-amyloid peptide.

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12 December 2020

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

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12 December 2020

Cerebral amyloid induces aberrant axonal sprouting and ectopic terminal formation in amyloid precursor protein transgenic mice.

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12 December 2020

Specific spatial learning deficits become severe with age in beta -amyloid precursor protein transgenic mice that harbor diffuse beta -amyloid deposits but do not form plaques

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12 December 2020

Nicotine enhances the depressive actions of A beta 1-40 on long-term potentiation in the rat hippocampal CA1 region in vivo

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12 December 2020

Endogenous beta-amyloid production in presenilin-deficient embryonic mouse fibroblasts

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12 December 2020

Iron accumulation in Alzheimer disease is a source of redox-generated free radicals

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12 December 2020

Mice deficient in BACE1, the Alzheimer's beta-secretase, have normal phenotype and abolished beta-amyloid generation

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12 December 2020

10.2165/00002512-200421100-00001

Identifiers

DOI

1 reference

PubMed ID

15287821

Dimensions Publication ID

10 August 2017

0 references

1 reference

PubMed ID

15287821