Extracellular Subunit Interactions Control Transitions between Functional States of Acid-sensing Ion Channel 1a. (Q35859520)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26070563%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

title

Extracellular Subunit Interactions Control Transitions between Functional States of Acid-sensing Ion Channel 1a (English)

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17 February 2020

4

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17 February 2020

author name string

Karolina Gwiazda

series ordinal

1

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17 February 2020

Gaetano Bonifacio

series ordinal

2

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17 February 2020

Sabrina Vullo

series ordinal

3

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17 February 2020

language of work or name

English

0 references

publication date

12 June 2015

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Journal of Biological Chemistry

17 February 2020

published in

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17 February 2020

volume

290

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17 February 2020

issue

29

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17 February 2020

page(s)

17956-17966

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Acid-sensing ion channel (ASIC) 1a/2a heteromers have a flexible 2:1/1:2 stoichiometry

17 February 2020

cites work

1 reference

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X-Ray Structure of Acid-Sensing Ion Channel 1–Snake Toxin Complex Reveals Open State of a Na+-Selective Channel

27 July 2018

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Protonation controls ASIC1a activity via coordinated movements in multiple domains.

27 July 2018

1 reference

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Independent contribution of extracellular proton binding sites to ASIC1a activation.

27 July 2018

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Acid-sensing ion channels in pain and disease.

27 July 2018

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Subtype-specific modulation of acid-sensing ion channel (ASIC) function by 2-guanidine-4-methylquinazoline

27 July 2018

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Structural plasticity and dynamic selectivity of acid-sensing ion channel–spider toxin complexes

27 July 2018

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Relative transmembrane segment rearrangements during BK channel activation resolved by structurally assigned fluorophore-quencher pairing.

27 July 2018

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Structure of the acid-sensing ion channel 1 in complex with the gating modifier Psalmotoxin 1

27 July 2018

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A combined computational and functional approach identifies new residues involved in pH-dependent gating of ASIC1a.

27 July 2018

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Pore architecture and ion sites in acid-sensing ion channels and P2X receptors

27 July 2018

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Oxidant regulated inter-subunit disulfide bond formation between ASIC1a subunits

27 July 2018

1 reference

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Interaction of the aromatics Tyr-72/Trp-288 in the interface of the extracellular and transmembrane domains is essential for proton gating of acid-sensing ion channels

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505043

Candidate amino acids involved in H+ gating of acid-sensing ion channel 1a.

27 July 2018

1 reference

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Structure of acid-sensing ion channel 1 at 1.9 A resolution and low pH

27 July 2018

1 reference

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Potentiation of acid-sensing ion channels by sulfhydryl compounds.

27 July 2018

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ASIC1a-specific modulation of acid-sensing ion channels in mouse cortical neurons by redox reagents

27 July 2018

1 reference

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Neuroprotection in ischemia: blocking calcium-permeable acid-sensing ion channels.

27 July 2018

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UCSF Chimera--a visualization system for exploratory research and analysis

27 July 2018

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A new ER trafficking signal regulates the subunit stoichiometry of plasma membrane K(ATP) channels

27 July 2018

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A modulatory subunit of acid sensing ion channels in brain and dorsal root ganglion cells

27 July 2018

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BNaC1 and BNaC2 constitute a new family of human neuronal sodium channels related to degenerins and epithelial sodium channels

27 July 2018

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Amiloride and its analogs as tools in the study of ion transport

27 July 2018

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International Union of Basic and Clinical Pharmacology. XCI. structure, function, and pharmacology of acid-sensing ion channels and the epithelial Na+ channel

27 July 2018

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Permeating protons contribute to tachyphylaxis of the acid-sensing ion channel (ASIC) 1a.

24 September 2018

1 reference

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Trypsin cleaves acid-sensing ion channel 1a in a domain that is critical for channel gating

24 September 2018

1 reference

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Acid sensing ionic channels: modulation by redox reagents.

24 September 2018

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Acid-sensing ion channel 1 is localized in brain regions with high synaptic density and contributes to fear conditioning.

24 September 2018

1 reference

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Paradoxical stimulation of a DEG/ENaC channel by amiloride.

24 September 2018

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Molecular determinants of desensitization in an ENaC/degenerin channel

24 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26070563

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A receptor for protons in the membrane of sensory neurons may participate in nociception

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26070563

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M115.641688

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26070563%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

1 reference

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17 February 2020

PubMed publication ID

26070563

1 reference