Synaptic depression and aberrant excitatory network activity in Alzheimer's disease: two faces of the same coin? (Q35869170)

10 August 2017

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title

Synaptic depression and aberrant excitatory network activity in Alzheimer's disease: two faces of the same coin? (English)

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10 August 2017

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2

Lennart Mucke

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10 August 2017

Jorge J Palop

1

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10 August 2017

17 October 2009

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10 August 2017

NeuroMolecular Medicine

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10 August 2017

12

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10 August 2017

48-55

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10 August 2017

1

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https://scigraph.springernature.com/pub.10.1007/s12017-009-8097-7

10 August 2017

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Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease

11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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Natural oligomers of the Alzheimer amyloid-beta protein induce reversible synapse loss by modulating an NMDA-type glutamate receptor-dependent signaling pathway

11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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Molecular, structural, and functional characterization of Alzheimer's disease: evidence for a relationship between default activity, amyloid, and memory

11 July 2018

1 reference

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11 July 2018

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The molecular basis of memantine action in Alzheimer's disease and other neurologic disorders: low-affinity, uncompetitive antagonism

11 July 2018

1 reference

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Natural oligomers of the amyloid-beta protein specifically disrupt cognitive function

11 July 2018

1 reference

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Homeostatic plasticity in the developing nervous system

11 July 2018

1 reference

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Functional deactivations: Change with age and dementia of the Alzheimer type

11 July 2018

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Neuronal depletion of calcium-dependent proteins in the dentate gyrus is tightly linked to Alzheimer's disease-related cognitive deficits

11 July 2018

1 reference

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APP processing and synaptic function

11 July 2018

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Staging of brain pathology related to sporadic Parkinson's disease

11 July 2018

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Role of neurotrophins in central synapse formation and stabilization.

11 July 2018

1 reference

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Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

11 July 2018

1 reference

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Beta-amyloid activates the mitogen-activated protein kinase cascade via hippocampal alpha7 nicotinic acetylcholine receptors: In vitro and in vivo mechanisms related to Alzheimer's disease

11 July 2018

1 reference

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Abnormal glutamate transport function in mutant amyloid precursor protein transgenic mice

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319077

Plaque-independent disruption of neural circuits in Alzheimer's disease mouse models

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319077

Activity-dependent scaling of quantal amplitude in neocortical neurons

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319077

Impairment of glucose and glutamate transport and induction of mitochondrial oxidative stress and dysfunction in synaptosomes by amyloid beta-peptide: role of the lipid peroxidation product 4-hydroxynonenal.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319077

beta-Amyloid selectively augments NMDA receptor-mediated synaptic transmission in rat hippocampus.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319077

Senile plaques in temporal lobe epilepsy.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319077

Amyloid beta-peptide impairs ion-motive ATPase activities: evidence for a role in loss of neuronal Ca2+ homeostasis and cell death.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319077

Excitotoxicity and the NMDA receptor--still lethal after eight years

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319077

Neuropathological stageing of Alzheimer-related changes

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319077

beta-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319077

Amyloid beta-induced neuronal hyperexcitability triggers progressive epilepsy.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319077

Clusters of hyperactive neurons near amyloid plaques in a mouse model of Alzheimer's disease.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319077

Memantine treatment in patients with mild to moderate Alzheimer's disease already receiving a cholinesterase inhibitor: a randomized, double-blind, placebo-controlled trial

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319077

Pore-forming proteins share structural and functional homology with amyloid oligomers.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319077

Increased brain activation during working memory in cognitively intact adults with the APOE epsilon4 allele

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319077

Effects of secreted oligomers of amyloid beta-protein on hippocampal synaptic plasticity: a potent role for trimers.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319077

Synaptic activity regulates interstitial fluid amyloid-beta levels in vivo.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319077

Impaired synaptic plasticity and learning in aged amyloid precursor protein transgenic mice.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319077

beta-Amyloid peptide-derived, oxygen-dependent free radicals inhibit glutamate uptake in cultured astrocytes: implications for Alzheimer's disease.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319077

[11C]PIB in a nondemented population: Potential antecedent marker of Alzheimer disease

24 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19838821

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1007/S12017-009-8097-7

1 reference

10 August 2017

1 reference

10 August 2017

1 reference

PMCID

3319077