Gene transfer in tissue repair: status, challenges and future directions (Q35873744)

10 August 2017

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title

Gene transfer in tissue repair: status, challenges and future directions (English)

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10 August 2017

Sabine A Eming

1

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10 August 2017

Thomas Krieg

series ordinal

2

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10 August 2017

Jeffrey M Davidson

series ordinal

3

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10 August 2017

language of work or name

English

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publication date

1 September 2004

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Expert Opinion on Biological Therapy

10 August 2017

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10 August 2017

4

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10 August 2017

9

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10 August 2017

1373-1386

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Wound healing--aiming for perfect skin regeneration

10 August 2017

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

21 January 2018

Cutaneous wound healing

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

Selective pick-up of increased iron by deferoxamine-coupled cellulose abrogates the iron-driven induction of matrix-degrading metalloproteinase 1 and lipid peroxidation in human dermal fibroblasts in vitro: a new dressing concept

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

Leukocyte proteinases in wound healing: roles in physiologic and pathologic processes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

Wound fluid from venous leg ulcers degrades plasminogen and reduces plasmin generation by keratinocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

Wound pathophysiology, infection and therapeutic options

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

Pseudomonas aeruginosa exoenzyme S, a bifunctional type-III secreted cytotoxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

Biomaterials in drug delivery and tissue engineering: one laboratory's experience

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

The basic science of gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

Therapeutic gene delivery to the skin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

Gene therapy with viral vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

A brief history of gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

In vivo assessment of gene delivery to keratinocytes by lentiviral vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

Lentivectors for regulated and reversible cutaneous gene delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

Genetically modified skin fibroblasts persist long after transplantation but gradually inactivate introduced genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

Concepts and strategies for human gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

Lack of expression from a retroviral vector after transduction of murine hematopoietic stem cells is associated with methylation in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

Safe and efficient generation of recombinant retroviruses with amphotropic and ecotropic host ranges

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

Gene therapy. Second child in French trial is found to have leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

Survival of cultured allografts in patients with burns assessed with probe specific for Y chromosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

Adenoviruses as gene-delivery vehicles

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

Second-generation adenovirus vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

Genomic DNA transfer with a high-capacity adenovirus vector results in improved in vivo gene expression and decreased toxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

Cellular immune response to adenoviral vector infected cells does not require de novo viral gene expression: implications for gene therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

The function of herpes simplex virus genes: a primer for genetic engineering of novel vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

21 January 2018

Gene therapy in the CNS.

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

Stable nonviral genetic correction of inherited human skin disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

Transfection with aFGF cDNA improves wound healing

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

Efficient gene expression in skin wound sites following local plasmid injection

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

The majority of keratinocytes incorporate intradermally injected plasmid DNA regardless of size but only a small proportion of cells can express the gene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

Puncture-mediated gene transfer to the skin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

High-velocity microprojectiles for delivering nucleic acids into living cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

In vivo and in vitro gene transfer to mammalian somatic cells by particle bombardment

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

Introduction of foreign genes into tissues of living mice by DNA-coated microprojectiles

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

In vivo promoter activity and transgene expression in mammalian somatic tissues evaluated by using particle bombardment

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

In vivo cytokine gene transfer by gene gun reduces tumor growth in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

Gene gun and other non-viral approaches for cancer gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

Particle-mediated gene therapy of wounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

Cationic liposome-mediated transfection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

The feasibility of targeted selective gene therapy of the hair follicle

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

Gene therapy for tissue repair: approaches and prospects

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

Cell-mediated DNA transport between distant inflammatory sites following intradermal DNA immunization in the presence of adjuvant

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

Matrix immobilization enhances the tissue repair activity of growth factor gene therapy vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

Transcriptional targeting of adenoviral gene delivery into migrating wound keratinocytes using FiRE, a growth factor-inducible regulatory element

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

Tight control of gene expression in mammalian cells by tetracycline-responsive promoters

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

Transcriptional activation by tetracyclines in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

Ecdysone-inducible gene expression in mammalian cells and transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

A regulatory system for use in gene transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

Development of gene-switch transgenic mice that inducibly express transforming growth factor beta1 in the epidermis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

A humanized system for pharmacologic control of gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

Inducible gene expression and protein translocation using nontoxic ligands identified by a mammalian three-hybrid screen

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

Topical colchicine selection of keratinocytes transduced with the multidrug resistance gene (MDR1) can sustain and enhance transgene expression in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

Genetically modified human epidermis overexpressing PDGF-A directs the development of a cellular and vascular connective tissue stroma when transplanted to athymic mice--implications for the use of genetically modified keratinocytes to modulate derm

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

Genetically modified human keratinocytes overexpressing PDGF-A enhance the performance of a composite skin graft

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

Expression of vascular endothelial growth factor from a defective herpes simplex virus type 1 amplicon vector induces angiogenesis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

Genetically modified fibroblasts induce angiogenesis in the rat epigastric island flap

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

In vivo transduction of mouse epidermis with recombinant retroviral vectors: implications for cutaneous gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

Stroma formation and angiogenesis by overexpression of growth factors, cytokines, and proteolytic enzymes in human skin grafted to SCID mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

Particle-mediated gene transfer with transforming growth factor-beta1 cDNAs enhances wound repair in rat skin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

Therapeutic success and efficacy of nonviral liposomal cDNA gene transfer to the skin in vivo is dose dependent

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

Reversal of impaired wound repair in iNOS-deficient mice by topical adenoviral-mediated iNOS gene transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

Human mesenchymal stem cells engraft and demonstrate site-specific differentiation after in utero transplantation in sheep

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

Gene intervention in ligament and tendon: current status, challenges, future directions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

Decorin antisense gene therapy improves functional healing of early rabbit ligament scar with enhanced collagen fibrillogenesis in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

Early biological effect of in vivo gene transfer of platelet-derived growth factor (PDGF)-B into healing patellar ligament

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

Gene-based approaches for the repair of articular cartilage

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

Transplantation of transduced chondrocytes protects articular cartilage from interleukin 1-induced extracellular matrix degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

Recombinant adeno-associated virus vectors efficiently and persistently transduce chondrocytes in normal and osteoarthritic human articular cartilage

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

Use of an active intra-abdominal drain in 67 horses

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

Acceleration of cartilage repair by genetically modified chondrocytes over expressing bone morphogenetic protein-7.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

Expression of human bone morphogenic protein 7 in primary rabbit periosteal cells: potential utility in gene therapy for osteochondral repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

Articular cartilage repair by gene therapy using growth factor-producing mesenchymal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

Gene therapy for arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

Adenoviral and adeno-associated viral transfer of genes to the peripheral nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

An adenoviral vector can transfer lacZ expression into Schwann cells in culture and in sciatic nerve

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

Adenoviral vector-mediated GDNF gene transfer prevents death of adult facial motoneurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

Generation of a novel proteolysis resistant vascular endothelial growth factor165 variant by a site-directed mutation at the plasmin sensitive cleavage site.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

Induction of hypervascularity without leakage or inflammation in transgenic mice overexpressing hypoxia-inducible factor-1alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

The transcription factor Egr-1: a potential drug in wound healing and tissue repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

Transcriptional mechanisms of chondrocyte differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

Transcriptional cross-talk between Smad, ERK1/2, and p38 mitogen-activated protein kinase pathways regulates transforming growth factor-beta-induced aggrecan gene expression in chondrogenic ATDC5 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

Mice lacking Smad3 show accelerated wound healing and an impaired local inflammatory response

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

A novel recombinant basic fibroblast growth factor and its secretion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.9.1373

10.1517/14712598.4.9.1373

21 January 2018

Identifiers

DOI

1 reference

10 August 2017

1 reference