CD44 in cancer progression: adhesion, migration and growth regulation (Q35875561)

10 August 2017

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title

CD44 in cancer progression: adhesion, migration and growth regulation (English)

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10 August 2017

Marhaba R

1

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PubMed ID

15339042

10 August 2017

Zöller M

series ordinal

2

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10 August 2017

1 March 2004

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Journal of Molecular Histology

10 August 2017

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10 August 2017

35

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10 August 2017

3

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10 August 2017

211-231

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The cytoplasmic tail of CD44 is required for basolateral localization in epithelial MDCK cells but does not mediate association with the detergent-insoluble cytoskeleton of fibroblasts

10 August 2017

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12 December 2020

CD44 regulates hematopoietic progenitor distribution, granuloma formation, and tumorigenicity.

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12 December 2020

The CD44 proteins in embryonic development and in cancer

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12 December 2020

Co-stimulation and counter-stimulation: lipid raft clustering controls TCR signaling and functional outcomes

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12 December 2020

A CD44 survival pathway triggers chemoresistance via lyn kinase and phosphoinositide 3-kinase/Akt in colon carcinoma cells.

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12 December 2020

CD44 exhibits a cell type dependent interaction with triton X-100 insoluble, lipid rich, plasma membrane domains

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12 December 2020

Molecular cloning and expression of Pgp-1. The mouse homolog of the human H-CAM (Hermes) lymphocyte homing receptor

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12 December 2020

A kinase-regulated PDZ-domain interaction controls endocytic sorting of the beta2-adrenergic receptor

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12 December 2020

Regulation of cytokine signaling by B cell antigen receptor and CD40-controlled expression of heparan sulfate proteoglycans

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12 December 2020

Heparin-binding epidermal growth factor-like growth factor in hippocampus: modulation of expression by seizures and anti-excitotoxic action

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12 December 2020

Cell interaction molecules and cytokines which participate in B lymphopoiesis

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12 December 2020

Hyaluronan oligosaccharides inhibit anchorage-independent growth of tumor cells by suppressing the phosphoinositide 3-kinase/Akt cell survival pathway

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12 December 2020

Aggregation of lipid rafts accompanies signaling via the T cell antigen receptor

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12 December 2020

In vivo and in vitro specificity of protein tyrosine kinases for immunoglobulin G receptor (FcgammaRII) phosphorylation

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12 December 2020

CD44H regulates tumor cell migration on hyaluronate-coated substrate

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12 December 2020

Prevention of tumor metastasis formation by anti-variant CD44.

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12 December 2020

CD44 interaction with tiam1 promotes Rac1 signaling and hyaluronic acid-mediated breast tumor cell migration

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12 December 2020

Lipid rafts mediate biosynthetic transport to the T lymphocyte uropod subdomain and are necessary for uropod integrity and function

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12 December 2020

ERM family members as molecular linkers between the cell surface glycoprotein CD44 and actin-based cytoskeletons

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12 December 2020

CD44 and its ligand hyaluronate mediate rolling under physiologic flow: a novel lymphocyte-endothelial cell primary adhesion pathway

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12 December 2020

Post-translational protein modification and expression of ankyrin-binding site(s) in GP85 (Pgp-1/CD44) and its biosynthetic precursors during T-lymphoma membrane biosynthesis

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12 December 2020

CD44 isoforms containing exon V3 are responsible for the presentation of heparin-binding growth factor

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12 December 2020

Participation in normal immune responses of a metastasis-inducing splice variant of CD44

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12 December 2020

Localization of matrix metalloproteinase 9 to the cell surface provides a mechanism for CD44-mediated tumor invasion

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12 December 2020

The B cell antigen receptor in B-cell development

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12 December 2020

CD44 signaling through p56lck involves lateral association with CD4 in human CD4+ T cells

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12 December 2020

Soluble osteopontin inhibits apoptosis of adherent endothelial cells deprived of growth factors

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12 December 2020

Enhanced osteopontin expression and macrophage infiltration in MRL-Fas(lpr) mice with lupus nephritis

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12 December 2020

A lymphoid cell surface glycoprotein involved in endothelial cell recognition and lymphocyte homing in man.

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12 December 2020

The role of the CD44/ezrin complex in cancer metastasis

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12 December 2020

CD44 is not an adhesive receptor for osteopontin

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12 December 2020

Ras oncoprotein induces CD44 cleavage through phosphoinositide 3-OH kinase and the rho family of small G proteins

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12 December 2020

Intracellular osteopontin is an integral component of the CD44-ERM complex involved in cell migration

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12 December 2020

CD44 expression on murine tissues

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12 December 2020

CD44 is required for two consecutive steps in HGF/c-Met signaling.

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12 December 2020

Regulated clustering of variant CD44 proteins increases their hyaluronate binding capacity

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12 December 2020

Functional domains in tetraspanin proteins

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12 December 2020

Induction of apoptosis of metastatic mammary carcinoma cells in vivo by disruption of tumor cell surface CD44 function

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12 December 2020

CD44v10 interaction with Rho-kinase (ROK) activates inositol 1,4,5-triphosphate (IP3) receptor-mediated Ca2+ signaling during hyaluronan (HA)-induced endothelial cell migration

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12 December 2020

Perturbation of hyaluronan interactions by soluble CD44 inhibits growth of murine mammary carcinoma cells in ascites

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12 December 2020

Identification of a common hyaluronan binding motif in the hyaluronan binding proteins RHAMM, CD44 and link protein.

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12 December 2020

Isolation and DNA sequence of a cDNA clone encoding a lymphocyte adhesion receptor for high endothelium

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12 December 2020

Retention of prominin in microvilli reveals distinct cholesterol-based lipid micro-domains in the apical plasma membrane.

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12 December 2020

Engineered mutants of HGF/SF with reduced binding to heparan sulphate proteoglycans, decreased clearance and enhanced activity in vivo

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12 December 2020

Membrane-cytoskeleton interactions during the formation of the immunological synapse and subsequent T-cell activation

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12 December 2020

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12 December 2020

Annexins: what are they good for?

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12 December 2020

Merlin phosphorylation by p21-activated kinase 2 and effects of phosphorylation on merlin localization

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12 December 2020

CD44 and its partners in metastasis

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12 December 2020

Selective suppression of CD44 in keratinocytes of mice bearing an antisense CD44 transgene driven by a tissue-specific promoter disrupts hyaluronate metabolism in the skin and impairs keratinocyte proliferation

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12 December 2020

Transient CD44 variant isoform expression and reduction in CD4(+)/CD25(+) regulatory T cells in C3H/HeJ mice with alopecia areata

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12 December 2020

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12 December 2020

Signaling properties of hyaluronan receptors

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12 December 2020

CD44 variants but not CD44s cooperate with beta1-containing integrins to permit cells to bind to osteopontin independently of arginine-glycine-aspartic acid, thereby stimulating cell motility and chemotaxis

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12 December 2020

Confirmation by peptide sequence and co-expression on various cell types of the identity of CD44 and P85 glycoprotein

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12 December 2020

Interaction between the adhesion receptor, CD44, and the oncogene product, p185HER2, promotes human ovarian tumor cell activation

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12 December 2020

T-cell-receptor-independent activation of cytolytic activity of cytotoxic T lymphocytes mediated through CD44 and gp90MEL-14.

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12 December 2020

CD44v(3,8-10) is involved in cytoskeleton-mediated tumor cell migration and matrix metalloproteinase (MMP-9) association in metastatic breast cancer cells

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12 December 2020

Hyaluronate can function as a cell adhesion molecule and CD44 participates in hyaluronate recognition

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12 December 2020

Functions of lipid rafts in biological membranes

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12 December 2020

Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product

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12 December 2020

Hyaluronan activates cell motility of v-Src-transformed cells via Ras-mitogen-activated protein kinase and phosphoinositide 3-kinase-Akt in a tumor-specific manner

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12 December 2020

Increased resistance to collagen-induced arthritis in CD44-deficient DBA/1 mice

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12 December 2020

A cell-surface molecule involved in organ-specific homing of lymphocytes

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12 December 2020

Group A Streptococcus tissue invasion by CD44-mediated cell signalling

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12 December 2020

Ezrin/radixin/moesin (ERM) proteins bind to a positively charged amino acid cluster in the juxta-membrane cytoplasmic domain of CD44, CD43, and ICAM-2

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12 December 2020

Murine cell surface glycoproteins. Purification of the polymorphic Pgp-1 antigen and analysis of its expression on macrophages and other myeloid cells.

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12 December 2020

CD44 signaling through focal adhesion kinase and its anti-apoptotic effect

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12 December 2020

Identification of the ankyrin-binding domain of the mouse T-lymphoma cell inositol 1,4,5-trisphosphate (IP3) receptor and its role in the regulation of IP3-mediated internal Ca2+ release

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12 December 2020

Multiple kinases mediate T-cell-receptor signaling

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12 December 2020

Joint features of metastasis formation and lymphocyte maturation and activation

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12 December 2020

Lymphocyte adhesion to endothelium

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12 December 2020

The osteopontin-CD44 survival signal involves activation of the phosphatidylinositol 3-kinase/Akt signaling pathway

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12 December 2020

Downregulation of c-Jun expression and cell cycle regulatory molecules in acute myeloid leukemia cells upon CD44 ligation.

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12 December 2020

Severe neuropathies in mice with targeted mutations in the ErbB3 receptor

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12 December 2020

Transmembrane domain of CD44 is required for its detergent insolubility in fibroblasts.

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12 December 2020

Formation of functional cell membrane domains: the interplay of lipid- and protein-mediated interactions

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12 December 2020

Ligation of the CD44 adhesion molecule inhibits drug-induced apoptosis in human myeloid leukemia cells.

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12 December 2020

Genomic structure of DNA encoding the lymphocyte homing receptor CD44 reveals at least 12 alternatively spliced exons

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12 December 2020

Antibody-induced activation of the hyaluronan receptor function of CD44 requires multivalent binding by antibody

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12 December 2020

Hyaluronan-dependent cell migration can be blocked by a CD44 cytoplasmic domain peptide containing a phosphoserine at position 325

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12 December 2020

The cDNA sequence of mouse Pgp-1 and homology to human CD44 cell surface antigen and proteoglycan core/link proteins

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12 December 2020

Expression of CD44 in Apc and Tcf mutant mice implies regulation by the WNT pathway

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12 December 2020

Characterization of the heparan sulfate and chondroitin sulfate assembly sites in CD44

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12 December 2020

Requirements for signal delivery through CD44: analysis using CD44-Fas chimeric proteins

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12 December 2020

Hyaluronic acid (HA) binding to CD44 activates Rac1 and induces lamellipodia outgrowth

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12 December 2020

Characterization of the class III collagen receptor, a phosphorylated, transmembrane glycoprotein expressed in nucleated human cells

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12 December 2020

Phosphorylation-dependent interaction of osteopontin with its receptors regulates macrophage migration and activation.

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12 December 2020

The selectins: vascular adhesion molecules

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12 December 2020

Hyaluronan, CD44 and its variant exons in human trophoblast invasion and placental angiogenesis

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12 December 2020

Redox-linked signal transduction pathways for protein tyrosine kinase activation

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12 December 2020

Layilin, a novel integral membrane protein, is a hyaluronan receptor

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12 December 2020

Hyaluronate-enhanced hematopoiesis: two different receptors trigger the release of interleukin-1beta and interleukin-6 from bone marrow macrophages.

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12 December 2020

CD44 isoforms in normal and leukemic hematopoiesis.

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12 December 2020

ERM proteins and merlin: integrators at the cell cortex

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12 December 2020

CD44 variant isoforms are preferentially expressed in basal epithelia of non-malignant human fetal and adult tissues

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12 December 2020

Functional significance of CD9 association with beta 1 integrins in human epidermal keratinocytes

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12 December 2020

Activation of Src family kinases by colony stimulating factor-1, and their association with its receptor

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12 December 2020

Signaling through sphingolipid microdomains of the plasma membrane: the concept of signaling platform

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12 December 2020

Phorbol myristate acetate stimulates the dimerization of CD44 involving a cysteine in the transmembrane domain

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12 December 2020

Functional design in the actin cytoskeleton

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12 December 2020

The ankyrin-binding domain of CD44s is involved in regulating hyaluronic acid-mediated functions and prostate tumor cell transformation.

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12 December 2020

CD44 supports T cell proliferation and apoptosis by apposition of protein kinases

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12 December 2020

Glycosylation provides both stimulatory and inhibitory effects on cell surface and soluble CD44 binding to hyaluronan

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12 December 2020

Lymphocyte interactions with extracellular matrix

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12 December 2020

Direct binding of the Na--H exchanger NHE1 to ERM proteins regulates the cortical cytoskeleton and cell shape independently of H(+) translocation

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12 December 2020

CD44-mediated neutrophil apoptosis in the rat

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12 December 2020

A splice variant of CD44 expressed in the apical ectodermal ridge presents fibroblast growth factors to limb mesenchyme and is required for limb outgrowth

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12 December 2020

Signal-dependent regulation of splicing via phosphorylation of Sam68

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12 December 2020

CD44 interaction with c-Src kinase promotes cortactin-mediated cytoskeleton function and hyaluronic acid-dependent ovarian tumor cell migration

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12 December 2020

A new cell adhesion mechanism involving hyaluronate and CD44.

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12 December 2020

Proteolytic release of CD44 intracellular domain and its role in the CD44 signaling pathway

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12 December 2020

The hematopoietic and epithelial forms of CD44 are distinct polypeptides with different adhesion potentials for hyaluronate-bearing cells

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12 December 2020

Osteopontin is involved in the initiation of cutaneous contact hypersensitivity by inducing Langerhans and dendritic cell migration to lymph nodes

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12 December 2020

CD44 expression by leucocytes in rheumatoid arthritis and modulation by specific antibody: implications for lymphocyte adhesion to endothelial cells and synoviocytes in vitro

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12 December 2020

A chemoattractant cytokine associated with granulomas in tuberculosis and silicosis

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12 December 2020

Redistribution of a major cell surface glycoprotein during cell movement

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12 December 2020

Adhesion molecules in hematopoietic cells.

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12 December 2020

CD44-deficient mice exhibit enhanced hepatitis after concanavalin A injection: evidence for involvement of CD44 in activation-induced cell death

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12 December 2020

Lipid rafts: cell surface platforms for T cell signaling

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12 December 2020

Acylation of the lymphoma transmembrane glycoprotein, GP85, may be required for GP85-ankyrin interaction

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12 December 2020

Differential involvement of the hyaluronan (HA) receptors CD44 and receptor for HA-mediated motility in endothelial cell function and angiogenesis

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12 December 2020

Reciprocal raft-receptor interactions and the assembly of adhesion complexes

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12 December 2020

Involvement of CD44 in cytoskeleton rearrangement and raft reorganization in T cells.

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12 December 2020

CD44: functional relevance to inflammation and malignancy

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12 December 2020

Interaction of CD44 variant isoforms with hyaluronic acid and the cytoskeleton in human prostate cancer cells

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12 December 2020

Regulation of alternative pre-mRNA splicing by the ERK MAP-kinase pathway

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12 December 2020

Integrins and signal transduction pathways: the road taken

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12 December 2020

Regulation of human CD44H and CD44E isoform binding to hyaluronan by phorbol myristate acetate and anti-CD44 monoclonal and polyclonal antibodies

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12 December 2020

A human lymphocyte homing receptor, the hermes antigen, is related to cartilage proteoglycan core and link proteins

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12 December 2020

Variations in the cytoskeletal interaction and posttranslational modification of the CD44 homing receptor in macrophages

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12 December 2020

The complex CD44 transcriptional unit: Alternative splicing of three internal exons generates the epithelial form of CD44

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12 December 2020

CD44 and hyaluronan binding by human myeloid cells

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12 December 2020

Hyaluronan: polysaccharide chaos to protein organisation

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12 December 2020

CD44 selectively associates with active Src family protein tyrosine kinases Lck and Fyn in glycosphingolipid-rich plasma membrane domains of human peripheral blood lymphocytes

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12 December 2020

Tyrosine kinase-dependent activation of human NK cell functions upon triggering through CD44 receptor

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12 December 2020

Association of ezrin with intercellular adhesion molecule-1 and -2 (ICAM-1 and ICAM-2). Regulation by phosphatidylinositol 4, 5-bisphosphate

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12 December 2020

Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase)

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12 December 2020

Cell death in the regulation of immune responses

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12 December 2020

Biochemical properties of glycoproteins involved in lymphocyte recognition of high endothelial venules in man.

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12 December 2020

Screening recombinant DNA libraries: a rapid and efficient method for isolating cDNA clones utilizing the PCR

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12 December 2020

Enhancement of natural killer activity by an antibody to CD44.

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12 December 2020

CD44-dependent lymphoma cell dissemination: a cell surface CD44 variant, rather than standard CD44, supports in vitro lymphoma cell rolling on hyaluronic acid substrate and its in vivo accumulation in the peripheral lymph nodes

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12 December 2020

Eta-1 (osteopontin): an early component of type-1 (cell-mediated) immunity

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12 December 2020

The role of the cytoplasmic domain in regulating CD44 function.

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12 December 2020

An antibody to CD44 enhances hematopoiesis in long-term marrow cultures

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12 December 2020

Evidence for differences in the mechanisms by which antibodies against CD44 promote adhesion of erythroid and granulopoietic progenitors to marrow stromal cells.

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12 December 2020

Membrane lipid organization is critical for human neutrophil polarization.

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12 December 2020

Transient absence of CD44 expression and delay in development by anti-CD44 treatment during ontogeny: a surrogate of an inducible knockout?

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12 December 2020

Diverse effects of anti-CD44 antibodies on the stromal cell-mediated support of normal but not leukaemic (CML) haemopoiesis in vitro

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12 December 2020

A new variant of glycoprotein CD44 confers metastatic potential to rat carcinoma cells

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12 December 2020

Induction of fibroblast apoptosis by anti-CD44 antibody: implications for the treatment of fibroproliferative lung disease

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12 December 2020

A novel PKC-regulated mechanism controls CD44 ezrin association and directional cell motility

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12 December 2020

The hyaluronate receptor is associated with actin filaments

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12 December 2020

The Jak/Stat pathway and urokinase receptor signaling in human aortic vascular smooth muscle cells.

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12 December 2020

Exclusion of CD43 from the immunological synapse is mediated by phosphorylation-regulated relocation of the cytoskeletal adaptor moesin

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12 December 2020

Molecular interactions between stromal cells and B lymphocyte precursors

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12 December 2020

Identification of two juxtamembrane autophosphorylation sites in the PDGF beta-receptor; involvement in the interaction with Src family tyrosine kinases

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12 December 2020

Structural heterogeneity of human Pgp-1 and its relationship with p85.

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12 December 2020

Cellular functions regulated by Src family kinases

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12 December 2020

Mitigation of delayed-type hypersensitivity reactions by a CD44 variant isoform v3-specific antibody: blockade of leukocyte egress

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12 December 2020

Adhesion-induced tyrosine phosphorylation of the p130 src substrate

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12 December 2020

Identification and characterization of a cell surface proteoglycan on keratinocytes

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12 December 2020

CD44 is the major peanut lectin-binding glycoprotein of human epidermal keratinocytes and plays a role in intercellular adhesion

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12 December 2020

Expression of CD44 isoforms carrying metastasis-associated sequences in newborn and adult rats

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12 December 2020

Homing receptors and vascular addressins: cell adhesion molecules that direct lymphocyte traffic.

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12 December 2020

CD44 splice variants: metastases meet lymphocytes

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12 December 2020

A link between ras and metastatic behavior of tumor cells: ras induces CD44 promoter activity and leads to low-level expression of metastasis-specific variants of CD44 in CREF cells.

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12 December 2020

Resolution of lung inflammation by CD44

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12 December 2020

CD44 anchors the assembly of matrilysin/MMP-7 with heparin-binding epidermal growth factor precursor and ErbB4 and regulates female reproductive organ remodeling

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12 December 2020

Requirement for CD44 in activated T cell extravasation into an inflammatory site

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12 December 2020

The lymphoma transmembrane glycoprotein GP85 (CD44) is a novel guanine nucleotide-binding protein which regulates GP85 (CD44)-ankyrin interaction

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12 December 2020

Cutaneous delayed-type hypersensitivity response is inhibited in transgenic mice with keratinocyte-specific CD44 expression defect

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12 December 2020

Localization of matrix metalloproteinase MMP-2 to the surface of invasive cells by interaction with integrin alpha v beta 3.

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12 December 2020

Heterogeneous ribonucleoprotein A1 is part of an exon-specific splice-silencing complex controlled by oncogenic signaling pathways

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12 December 2020

Generation of artificial proteoglycans containing glycosaminoglycan-modified CD44. Demonstration of the interaction between rantes and chondroitin sulfate

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12 December 2020

Ezrin is a downstream effector of trafficking PKC-integrin complexes involved in the control of cell motility

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12 December 2020

A role for moesin in polarity

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12 December 2020

Regulated CD44 cleavage under the control of protein kinase C, calcium influx, and the Rho family of small G proteins.

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12 December 2020

Tumor cell interactions with the extracellular matrix during invasion and metastasis

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12 December 2020

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

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12 December 2020

Low molecular weight hyaluronan induces malignant mesothelioma cell (MMC) proliferation and haptotaxis: role of CD44 receptor in MMC proliferation and haptotaxis.

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12 December 2020

Interleukin 15 induces endothelial hyaluronan expression in vitro and promotes activated T cell extravasation through a CD44-dependent pathway in vivo

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12 December 2020

Moesin interacts with the cytoplasmic region of intercellular adhesion molecule-3 and is redistributed to the uropod of T lymphocytes during cell polarization

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12 December 2020

Functional involvement of CD44, a family of cell adhesion molecules, in immune responses, tumour progression and haematopoiesis.

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12 December 2020

Monoclonal antibodies to human lymphocyte homing receptors define a novel class of adhesion molecules on diverse cell types

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12 December 2020

EGF receptor modifies cellular responses to hyaluronan in glioblastoma cell lines

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12 December 2020

ECM and cell surface proteolysis: regulating cellular ecology

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12 December 2020

Floating the raft hypothesis for immune receptors: access to rafts controls receptor signaling and trafficking

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12 December 2020

CD44 (Pgp-1) inhibits CD3 and dexamethasone-induced apoptosis

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12 December 2020

CD43 is associated with tyrosine kinase activity in human neutrophils

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12 December 2020

CD44: The hyaluronan receptor

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12 December 2020

Hyaluronan: a multifunctional, megaDalton, stealth molecule

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12 December 2020

Heparan sulfate proteoglycan isoforms of the CD44 hyaluronan receptor induced in human inflammatory macrophages can function as paracrine regulators of fibroblast growth factor action

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12 December 2020

Heparan Sulfate-modified CD44 Promotes Hepatocyte Growth Factor/Scatter Factor-induced Signal Transduction through the Receptor Tyrosine Kinase c-Met

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12 December 2020

Functional activity of CD44 isoforms in haemopoiesis of the rat.

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12 December 2020

The hyaluronan receptor, CD44.

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12 December 2020

Signaling through CD44 is mediated by tyrosine kinases. Association with p56lck in T lymphocytes

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12 December 2020

Differential stability of tetraspanin/tetraspanin interactions: role of palmitoylation

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12 December 2020

CD44 variant-specific antibodies trigger hemopoiesis by selective release of cytokines from bone marrow macrophages

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12 December 2020

Cell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-beta and promotes tumor invasion and angiogenesis

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12 December 2020

Multiple variants of the human lymphocyte homing receptor CD44 generated by insertions at a single site in the extracellular domain

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12 December 2020

CD44, a cell surface chondroitin sulfate proteoglycan, mediates binding of interferon-gamma and some of its biological effects on human vascular smooth muscle cells

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12 December 2020

Hyaluronan binding properties of a CD44 chimera containing the link module of TSG-6.

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12 December 2020

Human keratinocytes express a new CD44 core protein (CD44E) as a heparan-sulfate intrinsic membrane proteoglycan with additional exons

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12 December 2020

Osteopontin: a key cytokine in cell-mediated and granulomatous inflammation

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12 December 2020

CD44-deficient mice develop normally with changes in subpopulations and recirculation of lymphocyte subsets.

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12 December 2020

Involvement of CD44 in matrix metalloproteinase-2 regulation in human melanoma cells

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12 December 2020

The CD44-initiated pathway of T-cell extravasation uses VLA-4 but not LFA-1 for firm adhesion

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12 December 2020

Lipids, lipid domains and lipid–protein interactions in endocytic membrane traffic

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12 December 2020

CD44 cleavage induced by a membrane-associated metalloprotease plays a critical role in tumor cell migration

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12 December 2020

Physiological and molecular mechanisms of lymphocyte homing

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12 December 2020

ERM proteins and NF2 tumor suppressor: the Yin and Yang of cortical actin organization and cell growth signaling

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12 December 2020

Activation of beta1 integrins on CML progenitors reveals cooperation between beta1 integrins and CD44 in the regulation of adhesion and proliferation

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12 December 2020

Ankyrin-binding domain of CD44(GP85) is required for the expression of hyaluronic acid-mediated adhesion function

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12 December 2020

[Occurrence of CD44 and its isoforms under orthological and pathological conditions]

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12 December 2020

Role of CD44 in activation-induced cell death: CD44-deficient mice exhibit enhanced T cell response to conventional and superantigens

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12 December 2020

Lymphocyte CD44 binds the COOH-terminal heparin-binding domain of fibronectin

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12 December 2020

LIM-kinase 2 induces formation of stress fibres, focal adhesions and membrane blebs, dependent on its activation by Rho-associated kinase-catalysed phosphorylation at threonine-505

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12 December 2020

CD44 variant isoforms associate with tetraspanins and EpCAM.

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12 December 2020

CD44 associates with EGFR and erbB2 in metastasizing mammary carcinoma cells

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12 December 2020

CD44 mediates constitutive type I receptor signaling in cervical carcinoma cells

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12 December 2020

CD44 is involved in porcine natural cytotoxicity

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12 December 2020

Lipid rafts: bringing order to chaos

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12 December 2020

CD44: a multitude of isoforms with diverse functions

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12 December 2020

Coupling of osteopontin and its cell surface receptor CD44 to the cell survival response elicited by interleukin-3 or granulocyte-macrophage colony-stimulating factor

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12 December 2020

Treatment with an Anti-CD44v10-Specific Antibody Inhibits the Onset of Alopecia Areata in C3H/HeJ Mice

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12 December 2020

The transmembrane hyaluronate receptor (CD44): multiple functions, multiple forms

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12 December 2020

Rho, Rac and Cdc42 GTPases regulate the organization of the actin cytoskeleton

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12 December 2020

Caveolae, DIGs, and the dynamics of sphingolipid-cholesterol microdomains

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12 December 2020

The CD4 receptor is complexed in detergent lysates to a protein-tyrosine kinase (pp58) from human T lymphocytes

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12 December 2020

CD44 isoforms during differentiation and development

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12 December 2020

Site-directed mutagenesis of the arginine-glycine-aspartic acid sequence in osteopontin destroys cell adhesion and migration functions

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12 December 2020

Coupling of signal transduction to alternative pre-mRNA splicing by a composite splice regulator

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12 December 2020

[Functional studies of adhesion molecules on CD4-CD8- double negative T cells of autoimmune MRL/Mp-lpr/mice]

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12 December 2020

Assembly of pericellular matrices by COS-7 cells transfected with CD44 lymphocyte-homing receptor genes

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12 December 2020

Sequence of the bovine CD44 cDNA: comparison with human and mouse sequences.

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12 December 2020

Phosphorylation of CD44 in vivo requires both Ser323 and Ser325, but does not regulate membrane localization or cytoskeletal interaction in epithelial cells

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12 December 2020

Trans-acting factors regulate the expression of CD44 splice variants.

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12 December 2020

Fyn and ZAP-70 are required for Vav phosphorylation in T cells stimulated by antigen-presenting cells

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12 December 2020

Splicing choice from ten variant exons establishes CD44 variability

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12 December 2020

CD44 isoform expression mediated by alternative splicing: tissue-specific regulation in mice

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12 December 2020

Osteopontin as a means to cope with environmental insults: regulation of inflammation, tissue remodeling, and cell survival

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12 December 2020

The identification of a new alternative exon with highly restricted tissue expression in transcripts encoding the mouse Pgp-1 (CD44) homing receptor. Comparison of all 10 variable exons between mouse, human, and rat.

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12 December 2020

Lipid-binding proteins as stabilizers of membrane microdomains--possible physiological significance

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12 December 2020

CD44 is the principal cell surface receptor for hyaluronate

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12 December 2020

Lateral diffusion of an 80,000-dalton glycoprotein in the plasma membrane of murine fibroblasts: relationships to cell structure and function

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12 December 2020

Cytoskeleton-dependent membrane domain segregation during neutrophil polarization

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12 December 2020

Hyaluronan-binding proteins in development, tissue homeostasis, and disease

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12 December 2020

Expression of the palmitoylation-deficient CD151 weakens the association of alpha 3 beta 1 integrin with the tetraspanin-enriched microdomains and affects integrin-dependent signaling

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12 December 2020

The hyaluronate receptor is a member of the CD44 (H-CAM) family of cell surface glycoproteins

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12 December 2020

Involvement of CD44 exon v10 in B-cell activation

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12 December 2020

CD44 participates in the adhesion of human colorectal carcinoma cells to laminin and type IV collagen

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12 December 2020

Structural conversion between open and closed forms of radixin: low-angle shadowing electron microscopy.

1 reference

12 December 2020

Targeting dendritic cells with CD44 monoclonal antibodies selectively inhibits the proliferation of naive CD4+ T-helper cells by induction of FAS-independent T-cell apoptosis

1 reference

12 December 2020

Effects of anti-CD44 monoclonal antibodies on differentiation and apoptosis of human myeloid leukemia cell lines

1 reference

12 December 2020

Phosphorylation of adducin by Rho-kinase plays a crucial role in cell motility

1 reference

12 December 2020

ERM-dependent movement of CD43 defines a novel protein complex distal to the immunological synapse

1 reference

12 December 2020

Identification of hyaluronic acid binding sites in the extracellular domain of CD44

1 reference

12 December 2020

CD44 and other cell interaction molecules contributing to B lymphopoiesis.

1 reference

12 December 2020

Normal human tissues, in addition to some tumors, express multiple different CD44 isoforms.

1 reference

12 December 2020

Antibodies to CD44 trigger effector functions of human T cell clones

1 reference

12 December 2020

CD44: from adhesion molecules to signalling regulators

1 reference

12 December 2020

Proteoglycan forms of the lymphocyte homing receptor CD44 are alternatively spliced variants containing the v3 exon

1 reference

12 December 2020

Hyaluronate receptors mediating glioma cell migration and proliferation

1 reference

12 December 2020

A cell surface integral membrane glycoprotein of 85,000 mol wt (gp85) associated with triton X-100-insoluble cell skeleton

1 reference

12 December 2020

Chemotactic cytokines (chemokines) in human hepatitis and experimental hepatitis models: which ones play the crucial role?

1 reference

12 December 2020

Hematopoietic progenitor cell expression of the H-CAM (CD44) homing-associated adhesion molecule

1 reference

12 December 2020

CD44 and its interaction with extracellular matrix.

1 reference

12 December 2020

Role of the extracellular and cytoplasmic domains of CD44 in the rolling interaction of lymphoid cells with hyaluronan under physiologic flow

1 reference

12 December 2020

CD44 co-stimulates apoptosis in thymic lymphomas and T cell hybridomas

1 reference

12 December 2020

Multiple essential functions of neuregulin in development

1 reference

12 December 2020

Rho-associated kinase, a novel serine/threonine kinase, as a putative target for small GTP binding protein Rho

1 reference

12 December 2020

Coordinate expression of OPN and associated receptors during monocyte/macrophage differentiation of HL-60 cells

1 reference

12 December 2020

Activated human lymphocytes and aggressive non-Hodgkin's lymphomas express a homologue of the rat metastasis-associated variant of CD44

1 reference

12 December 2020

Blood cell cytoadhesion molecules

1 reference

12 December 2020

Molecular isoforms of murine CD44 and evidence that the membrane proximal domain is not critical for hyaluronate recognition

1 reference

12 December 2020

Characterization of a functional hyaluronan-binding domain from the human CD44 molecule expressed in Escherichia coli

1 reference

12 December 2020

Protein and lipid sorting from thetrans–Golgi network to the plasma membrane in polarized cells

1 reference

12 December 2020

Temporal activation of nontransmembrane protein-tyrosine kinases following mast cell Fc epsilon RI engagement

1 reference

12 December 2020

Hyaluronan anchoring and regulation on the surface of vascular endothelial cells is mediated through the functionally active form of CD44.

1 reference

12 December 2020

Proteoglycans: many forms and many functions

1 reference

12 December 2020

Proteolytic cleavage of the CD44 adhesion molecule in multiple human tumors

1 reference

12 December 2020

Cell surface heparan sulfate proteoglycans from human vascular endothelial cells. Core protein characterization and antithrombin III binding properties

1 reference

12 December 2020

Effects of anti-CD44 monoclonal antibody on adhesion of erythroid leukemic cells (ELM-I-1) to hematopoietic supportive cells (MS-5): CD44, but not hyaluronate-mediated, cell-cell adhesion

1 reference

12 December 2020

CD44 stimulation down-regulates Fas expression and Fas-mediated apoptosis of lung cancer cells

1 reference

12 December 2020

CD44 deficiency leads to enhanced neutrophil migration and lung injury in Escherichia coli pneumonia in mice

1 reference

12 December 2020

A FERM domain governs apical confinement of PTP-BL in epithelial cells

1 reference

12 December 2020

Expression of adhesion molecules on human hematopoietic progenitor cells at different maturational stages

1 reference

12 December 2020

The CD44 protein family: roles in embryogenesis and tumor progression.

1 reference

12 December 2020

Lymphoma protein kinase C is associated with the transmembrane glycoprotein, GP85, and may function in GP85-ankyrin binding

1 reference

12 December 2020

A crucial role for CD44 in inflammation

1 reference

12 December 2020

Evidence for a role of osteopontin in macrophage infiltration in response to pathological stimuli in vivo

1 reference

12 December 2020

1 reference

12 December 2020

Identification of CD44 residues important for hyaluronan binding and delineation of the binding site

1 reference

12 December 2020

The liberation of CD44.

1 reference

12 December 2020

Glioma-associated hyaluronan induces apoptosis in dendritic cells via inducible nitric oxide synthase: implications for the use of dendritic cells for therapy of gliomas.

1 reference

12 December 2020

Monoclonal antibodies to Pgp-1/CD44 block lympho-hemopoiesis in long-term bone marrow cultures

1 reference

12 December 2020

CD44 can be activated to function as an hyaluronic acid receptor in normal murine T cells

1 reference

12 December 2020

CD44v7 interferes with activation-induced cell death by up-regulation of anti-apoptotic gene expression.

1 reference

12 December 2020

The COOH terminus of Rho-kinase negatively regulates rho-kinase activity.

1 reference

12 December 2020

A role for lipid rafts in immune cell signaling

1 reference

12 December 2020

Hyaluronan promotes CD44v3-Vav2 interaction with Grb2-p185(HER2) and induces Rac1 and Ras signaling during ovarian tumor cell migration and growth

1 reference

12 December 2020

Role of hyaluronan and CD44 in in vitro branching morphogenesis of ureteric bud cells

1 reference

12 December 2020

The Src family tyrosine kinases are required for platelet-derived growth factor-mediated signal transduction in NIH 3T3 cells

1 reference

12 December 2020

Rho-kinase (ROK) promotes CD44v(3,8-10)-ankyrin interaction and tumor cell migration in metastatic breast cancer cells

1 reference

12 December 2020

The hyaluronan receptor (CD44) participates in the uptake and degradation of hyaluronan

1 reference

12 December 2020

Adhesion of committed human hematopoietic progenitors to synthetic peptides from the C-terminal heparin-binding domain of fibronectin: cooperation between the integrin alpha 4 beta 1 and the CD44 adhesion receptor

1 reference

12 December 2020

CD44-initiated cell spreading induces Pyk2 phosphorylation, is mediated by Src family kinases, and is negatively regulated by CD45.

1 reference

12 December 2020

Identification and functional analysis of the ezrin-binding site in the hyaluronan receptor, CD44.

1 reference

12 December 2020

A family of cell-surface glycoproteins defined by a putative anti-endothelial cell receptor antibody in man.

1 reference

12 December 2020

Ligation of the CD44 adhesion molecule reverses blockage of differentiation in human acute myeloid leukemia

1 reference

12 December 2020

Abrogation of experimental colitis correlates with increased apoptosis in mice deficient for CD44 variant exon 7 (CD44v7).

1 reference

12 December 2020

A novel ligand for CD44 is sulfated proteoglycan

1 reference

12 December 2020

Engagement of variant CD44 confers resistance to anti-integrin antibody-mediated apoptosis in a colon carcinoma cell line

1 reference

12 December 2020

T-cell adhesion induced by proteoglycan-immobilized cytokine MIP-lβ

1 reference

12 December 2020

Direct involvement of ezrin/radixin/moesin (ERM)-binding membrane proteins in the organization of microvilli in collaboration with activated ERM proteins

1 reference

12 December 2020

Soluble CD44 inhibits melanoma tumor growth by blocking cell surface CD44 binding to hyaluronic acid

1 reference

12 December 2020

Requirement for CD44 in proliferation and homing of hematopoietic precursor cells

1 reference

12 December 2020

Signaling complex formation of CD44 with src-related kinases

1 reference

12 December 2020

Identification of mRNA that encodes an alternative form of H-CAM(CD44) in lymphoid and nonlymphoid tissues

1 reference

12 December 2020

The NF2 tumor suppressor gene product, merlin, mediates contact inhibition of growth through interactions with CD44

1 reference

12 December 2020

Gene expression patterns associated with the metastatic phenotype in rodent and human tumors

1 reference

12 December 2020

Hyaluronan promotes signaling interaction between CD44 and the transforming growth factor beta receptor I in metastatic breast tumor cells

1 reference

12 December 2020

Adhesive interactions in hemopoiesis

1 reference

12 December 2020

Analysis of CD44-containing lipid rafts: Recruitment of annexin II and stabilization by the actin cytoskeleton

1 reference

12 December 2020

Trafficking of CD44-deficient murine lymphocytes under normal and inflammatory conditions

1 reference

12 December 2020

CD44 enhances neuregulin signaling by Schwann cells

1 reference

12 December 2020

10.1023/B:HIJO.0000032354.94213.69

Identifiers

DOI

1 reference

10 August 2017

1 reference

PubMed ID

15339042