Differential regulation of CHOP-10/GADD153 gene expression by MAPK signaling in pancreatic beta-cells. (Q35880276)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17615236%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

title

Differential regulation of CHOP-10/GADD153 gene expression by MAPK signaling in pancreatic beta-cells (English)

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1 January 2020

5

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4

Marlon F Levy

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1 January 2020

3

Bashoo Naziruddin

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1 January 2020

author name string

Michael C Lawrence

series ordinal

1

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1 January 2020

Kathleen McGlynn

series ordinal

2

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1 January 2020

language of work or name

English

0 references

publication date

5 July 2007

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Proceedings of the National Academy of Sciences of the United States of America

1 January 2020

published in

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1 January 2020

volume

104

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issue

28

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page(s)

11518-11525

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Endoplasmic reticulum stress contributes to beta cell apoptosis in type 2 diabetes

1 January 2020

cites work

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Inhibition of glucose-stimulated activation of extracellular signal-regulated protein kinases 1 and 2 by epinephrine in pancreatic beta-cells

11 July 2018

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Mechanisms of pancreatic beta-cell death in type 1 and type 2 diabetes: many differences, few similarities

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Cytokines downregulate the sarcoendoplasmic reticulum pump Ca2+ ATPase 2b and deplete endoplasmic reticulum Ca2+, leading to induction of endoplasmic reticulum stress in pancreatic beta-cells

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CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum

11 July 2018

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The diabetes-linked transcription factor PAX4 promotes {beta}-cell proliferation and survival in rat and human islets

11 July 2018

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Five stages of evolving beta-cell dysfunction during progression to diabetes

11 July 2018

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Mitochondrial reactive oxygen species control the transcription factor CHOP-10/GADD153 and adipocyte differentiation: a mechanism for hypoxia-dependent effect

11 July 2018

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The MafA transcription factor appears to be responsible for tissue-specific expression of insulin

11 July 2018

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Differentially expressed Maf family transcription factors, c-Maf and MafA, activate glucagon and insulin gene expression in pancreatic islet alpha- and beta-cells

11 July 2018

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Induction of CHOP expression by amino acid limitation requires both ATF4 expression and ATF2 phosphorylation

11 July 2018

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Glucose-regulated gene expression maintaining the glucose-responsive state of beta-cells

11 July 2018

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MafA is a glucose-regulated and pancreatic beta-cell-specific transcriptional activator for the insulin gene

11 July 2018

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Nm23-H1 metastasis suppressor phosphorylation of kinase suppressor of Ras via a histidine protein kinase pathway

11 July 2018

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Transcriptional regulation of GATA-3 by an intronic regulatory region and fetal liver zinc finger protein 1

11 July 2018

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Identification of beta-cell-specific insulin gene transcription factor RIPE3b1 as mammalian MafA.

11 July 2018

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Targeted disruption of the Chop gene delays endoplasmic reticulum stress-mediated diabetes

11 July 2018

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Mechanism of oxidative stress-induced GADD153 gene expression in vascular smooth muscle cells

11 July 2018

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Genetic regulation of metabolic pathways in beta-cells disrupted by hyperglycemia

11 July 2018

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A highly conserved c-fms gene intronic element controls macrophage-specific and regulated expression

11 July 2018

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Nitric oxide-induced apoptosis in pancreatic beta cells is mediated by the endoplasmic reticulum stress pathway

11 July 2018

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Stress-inducible transcription factor CHOP/gadd153 induces apoptosis in mammalian cells via p38 kinase-dependent and -independent mechanisms

11 July 2018

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Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state

11 July 2018

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11 July 2018

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Role of C/EBP homologous protein (CHOP-10) in the programmed activation of CCAAT/enhancer-binding protein-beta during adipogenesis

11 July 2018

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CHOP/GADD153 gene expression response to cellular stresses inhibited by prior exposure to ultraviolet light wavelength band C (UVC). Inhibitory sequence mediating the UVC response localized to exon 1.

11 July 2018

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Amino acids control mammalian gene transcription: activating transcription factor 2 is essential for the amino acid responsiveness of the CHOP promoter

11 July 2018

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11 July 2018

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11 July 2018

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Complexes containing activating transcription factor (ATF)/cAMP-responsive-element-binding protein (CREB) interact with the CCAAT/enhancer-binding protein (C/EBP)-ATF composite site to regulate Gadd153 expression during the stress response

11 July 2018

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11 July 2018

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Pancreatic beta-cell-specific repression of insulin gene transcription by CCAAT/enhancer-binding protein beta. Inhibitory interactions with basic helix-loop-helix transcription factor E47.

11 July 2018

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gadd153/Chop10, a potential target gene of the transcriptional repressor ATF3.

11 July 2018

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Activation of mitogen-activating protein kinase by glucose is not required for insulin secretion

11 July 2018

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Regulation of insulin preRNA splicing by glucose

11 July 2018

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Glucose promotes survival of rat pancreatic beta cells by activating synthesis of proteins which suppress a constitutive apoptotic program

11 July 2018

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GADD153/CHOP, a DNA damage-inducible protein, reduced CAAT/enhancer binding protein activities and increased apoptosis in 32D c13 myeloid cells.

11 July 2018

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Induction of the mammalian stress response gene GADD153 by oxidative stress: role of AP-1 element

11 July 2018

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Regulation of the C/EBP-related gene gadd153 by glucose deprivation

11 July 2018

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Induction of GADD153, a CCAAT/enhancer-binding protein (C/EBP)-related gene, during the acute phase response in rats. Evidence for the involvement of C/EBPs in regulating its expression.

11 July 2018

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Glucose, other secretagogues, and nerve growth factor stimulate mitogen-activated protein kinase in the insulin-secreting beta-cell line, INS-1.

11 July 2018

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The reduction of insulin gene transcription in HIT-T15 beta cells chronically exposed to high glucose concentration is associated with the loss of RIPE3b1 and STF-1 transcription factor expression

11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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Cell-specific and ubiquitous factors are responsible for the enhancer activity of the rat insulin II gene

11 July 2018

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CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcription

11 July 2018

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11 July 2018

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Regulation of insulin gene transcription by ERK1 and ERK2 in pancreatic beta cells

24 September 2018

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Regulation of ERK1 and ERK2 by glucose and peptide hormones in pancreatic beta cells

24 September 2018

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Increased expression of antioxidant and antiapoptotic genes in islets that may contribute to beta-cell survival during chronic hyperglycemia

24 September 2018

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Intraductal collagenase delivery into the human pancreas using syringe loading or controlled perfusion.

24 September 2018

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Induction of lens differentiation by activation of a bZIP transcription factor, L-Maf.

24 September 2018

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Amino Acid Limitation Induces Expression ofCHOP, a CCAAT/Enhancer Binding Protein-related Gene, at Both Transcriptional and Post-transcriptional Levels

24 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0704618104

Effect of serum on the down-regulation of CHOP-10 during differentiation of 3T3-L1 preadipocytes

21 January 2018

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12 December 2020

A cis-element in the 5' untranslated region of the preproinsulin mRNA (ppIGE) is required for glucose regulation of proinsulin translation

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12 December 2020

Improved human islet isolation using a new enzyme blend, liberase

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12 December 2020

Fas- or ceramide-induced apoptosis is mediated by a Rac1-regulated activation of Jun N-terminal kinase/p38 kinases and GADD153

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12 December 2020

Chronic hyperglycemia triggers loss of pancreatic beta cell differentiation in an animal model of diabetes

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12 December 2020

Identifiers

DOI

10.1073/PNAS.0704618104

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17615236%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

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24 November 2022

mapped directly with Wikidata item

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1 January 2020

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