Dengue Virus Nonstructural Protein 1-Induced Antibodies Cross-React with Human Plasminogen and Enhance Its Activation (Q35880303)

10 August 2017

Dengue Virus Nonstructural Protein 1-Induced Antibodies Cross-React with Human Plasminogen and Enhance Its Activation (English)

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modulation by virus of host process

10 August 2017

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dengue virus protein NS1

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based on heuristic

inferred from abstract

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author

Trai-Ming Yeh

series ordinal

5

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10 August 2017

3

Yee-Shin Lin

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10 August 2017

1

Yung-Chun Chuang

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10 August 2017

Jessica Lin

2

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PubMed ID

26712948

10 August 2017

Shuying Wang

series ordinal

4

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PubMed ID

26712948

10 August 2017

language of work or name

English

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publication date

28 December 2015

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10 August 2017

Journal of Immunology

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10 August 2017

196

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10 August 2017

3

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10 August 2017

1218-1226

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Dengue: a continuing global threat

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Structure of dengue virus: implications for flavivirus organization, maturation, and fusion

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The flavivirus NS1 protein: molecular and structural biology, immunology, role in pathogenesis and application as a diagnostic biomarker

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Immunolocalization of the dengue virus nonstructural glycoprotein NS1 suggests a role in viral RNA replication

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Dengue virus nonstructural protein 1 is expressed in a glycosyl-phosphatidylinositol-linked form that is capable of signal transduction

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Antagonism of the complement component C4 by flavivirus nonstructural protein NS1.

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1 reference

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Binding of flavivirus nonstructural protein NS1 to C4b binding protein modulates complement activation

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Dengue virus nonstructural protein NS1 binds to prothrombin/thrombin and inhibits prothrombin activation

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Endothelial Cell Sensitization by Death Receptor Fractions of an Anti-Dengue Nonstructural Protein 1 Antibody Induced Plasma Leakage, Coagulopathy, and Mortality in Mice

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Development of Cross-Reactive Antibodies to Plasminogen during the Immune Response to Dengue Virus Infection

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1 reference

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Dengue virus-induced autoantibodies bind to plasminogen and enhance its activation

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Molecular mimicry between virus and host and its implications for dengue disease pathogenesis

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Antibodies against thrombin in dengue patients contain both anti-thrombotic and pro-fibrinolytic activities.

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Correlation between detection of plasminogen cross-reactive antibodies and hemorrhage in dengue virus infection.

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Molecular mimicry between dengue virus and coagulation factors induces antibodies to inhibit thrombin activity and enhance fibrinolysis

21 January 2018

1 reference

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Flavivirus NS1 Structures Reveal Surfaces for Associations with Membranes and the Immune System

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The X-ray crystal structure of full-length human plasminogen

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Autoantibodies with enzymatic properties in human autoimmune diseases

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Catalytic activity of antibodies against factor VIII in patients with hemophilia A.

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Antibody-mediated catalysis: induction and therapeutic relevance

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Bacterial metastasis: the host plasminogen system in bacterial invasion

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The interaction between pathogens and the host coagulation system

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Deletion of the C-terminal region of dengue virus nonstructural protein 1 (NS1) abolishes anti-NS1-mediated platelet dysfunction and bleeding tendency

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Protection against dengue virus infection in mice by administration of antibodies against modified nonstructural protein 1.

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Dengue virus pathogenesis: an integrated view

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NS1: A corner piece in the dengue pathogenesis puzzle?

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Dengue virus NS1 protein activates cells via Toll-like receptor 4 and disrupts endothelial cell monolayer integrity

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Dengue virus NS1 triggers endothelial permeability and vascular leak that is prevented by NS1 vaccination

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Identifying protective dengue vaccines: guide to mastering an empirical process

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Current progress in dengue vaccines

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21 January 2018

Identifiers

DOI

10.4049/JIMMUNOL.1500057

1 reference

10 August 2017

1 reference

PubMed ID

26712948