Oncogenic KRAS impairs EGFR antibodies' efficiency by C/EBPβ-dependent suppression of EGFR expression (Q35882193)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22496619%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

title

Oncogenic KRAS impairs EGFR antibodies' efficiency by C/EBPβ-dependent suppression of EGFR expression (English)

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28 January 2020

9

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Paul Whi Parren

14

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author name string

Stefanie Derer

1

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28 January 2020

Sven Berger

2

1 reference

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28 January 2020

Martin Schlaeth

3

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28 January 2020

Tanja Schneider-Merck

4

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28 January 2020

Katja Klausz

5

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28 January 2020

Stefan Lohse

6

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28 January 2020

Marije B Overdijk

7

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28 January 2020

Michael Dechant

8

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28 January 2020

Iris Nagelmeier

10

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28 January 2020

Andreas H Scheel

11

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28 January 2020

Jeroen J Lammerts van Bueren

12

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28 January 2020

Jan G J van de Winkel

13

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28 January 2020

Matthias Peipp

15

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28 January 2020

Thomas Valerius

16

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28 January 2020

publication date

1 March 2012

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28 January 2020

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28 January 2020

volume

14

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28 January 2020

issue

3

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28 January 2020

page(s)

190-205

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describes a project that uses

28 January 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3323897/fullTextXML

inferred from PubMed Central ID database lookup

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11 July 2018

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Non-redundancy within the RAS oncogene family: insights into mutational disparities in cancer

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C/EBPbeta regulates transcription factors critical for proliferation and survival of multiple myeloma cells

11 July 2018

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Role of polymorphic Fc gamma receptor IIIa and EGFR expression level in cetuximab mediated, NK cell dependent in vitro cytotoxicity of head and neck squamous cell carcinoma cells

11 July 2018

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RasV12-mediated down-regulation of CCAAT/enhancer binding protein beta in immortalized fibroblasts requires loss of p19Arf and facilitates bypass of oncogene-induced senescence

11 July 2018

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American Society of Clinical Oncology provisional clinical opinion: testing for KRAS gene mutations in patients with metastatic colorectal carcinoma to predict response to anti-epidermal growth factor receptor monoclonal antibody therapy

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Ha-Ras transformation of MCF10A cells leads to repression of Singleminded-2s through NOTCH and C/EBPbeta.

11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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Epidermal growth factor inhibits growth of A431 human epidermoid carcinoma in serum-free cell culture

11 July 2018

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Characterization and sequence of the promoter region of the human epidermal growth factor receptor gene

11 July 2018

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11 July 2018

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Epidermal growth factor receptor (EGFR) antibody-induced antibody-dependent cellular cytotoxicity plays a prominent role in inhibiting tumorigenesis, even of tumor cells insensitive to EGFR signaling inhibition.

11 July 2018

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In vivo cytotoxicity of type I CD20 antibodies critically depends on Fc receptor ITAM signaling.

24 September 2018

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Protein overexpression and gene amplification of epidermal growth factor receptor in nonsmall cell lung carcinomas: Comparison of four commercially available antibodies by immunohistochemistry and fluorescence in situ hybridization study

24 September 2018

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Detection of KRAS oncogene in peripheral blood as a predictor of the response to cetuximab plus chemotherapy in patients with metastatic colorectal cancer.

24 September 2018

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Epidermal growth factor receptor gene copy number, K-ras mutation and pathological response to preoperative cetuximab, 5-FU and radiation therapy in locally advanced rectal cancer.

24 September 2018

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Differential regulation of elafin in normal and tumor-derived mammary epithelial cells is mediated by CCAAT/enhancer binding protein beta.

24 September 2018

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FCGR2A and FCGR3A polymorphisms associated with clinical outcome of epidermal growth factor receptor expressing metastatic colorectal cancer patients treated with single-agent cetuximab.

24 September 2018

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Gene copy number for epidermal growth factor receptor (EGFR) and clinical response to antiEGFR treatment in colorectal cancer: a cohort study

24 September 2018

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Human IgG2 Antibodies against Epidermal Growth Factor Receptor Effectively Trigger Antibody-Dependent Cellular Cytotoxicity but, in Contrast to IgG1, Only by Cells of Myeloid Lineage

24 September 2018

1 reference

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Complement-Dependent Tumor Cell Lysis Triggered by Combinations of Epidermal Growth Factor Receptor Antibodies

14 November 2018

1 reference

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SIGNAL TRANSDUCTION: Prelude to an Anniversary for the RAS Oncogene

14 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3323897

Expression of epiregulin and amphiregulin and K-ras mutation status predict disease control in metastatic colorectal cancer patients treated with cetuximab

14 November 2018

1 reference

12 December 2020

Epidermal growth factor receptor gene copy number and clinical outcome of metastatic colorectal cancer treated with panitumumab

1 reference

12 December 2020

Increased expression of the transcription factors CCAAT-enhancer binding protein-beta (C/EBBeta) and C/EBzeta (CHOP) correlate with invasiveness of human colorectal cancer

1 reference

12 December 2020

Expression of a translationally regulated, dominant-negative CCAAT/enhancer-binding protein beta isoform and up-regulation of the eukaryotic translation initiation factor 2alpha are correlated with neoplastic transformation of mammary epithelial cel

1 reference

12 December 2020

Overexpression of C/EBPbeta-LIP, a naturally occurring, dominant-negative transcription factor, in human breast cancer

1 reference

12 December 2020

Oncogenic Ras modulates epidermal growth factor responsiveness in endometrial carcinomas

1 reference

12 December 2020

Lack of usefulness of epidermal growth factor receptor expression determination for cetuximab therapy in patients with colorectal cancer

1 reference

12 December 2020

Phase I Pharmacokinetic and Pharmacodynamic Dose-Escalation Study of RG7160 (GA201), the First Glycoengineered Monoclonal Antibody Against the Epidermal Growth Factor Receptor, in Patients With Advanced Solid Tumors

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12 December 2020

Identifiers

DOI

10.1593/NEO.111636

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22496619%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22496619%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

PubMed publication ID

22496619

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22496619%20AND%20SRC:MED&resulttype=core&format=json