Interactions between the innate immune and blood coagulation systems (Q35885818)

10 August 2017

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title

Interactions between the innate immune and blood coagulation systems (English)

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10 August 2017

Charles T Esmon

1

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10 August 2017

1 October 2004

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10 August 2017

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10 August 2017

25

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10 August 2017

536-542

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10 August 2017

10

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CD1c-mediated T-cell recognition of isoprenoid glycolipids in Mycobacterium tuberculosis infection

10 August 2017

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12 December 2020

Protein C levels as a prognostic indicator of outcome in sepsis and related diseases

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12 December 2020

Introduction: are natural anticoagulants candidates for modulating the inflammatory response to endotoxin?

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12 December 2020

Systemic host responses in severe sepsis analyzed by causative microorganism and treatment effects of drotrecogin alfa (activated).

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12 December 2020

Protein C inhibitor is a potent inhibitor of the thrombin-thrombomodulin complex

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12 December 2020

Dysfunction of Endothelial Protein C Activation in Severe Meningococcal Sepsis

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12 December 2020

CD40L-CD40 interactions regulate endothelial cell surface tissue factor and thrombomodulin expression

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12 December 2020

The roles of protein C and thrombomodulin in the regulation of blood coagulation

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12 December 2020

Recombinant human antithrombin III improves survival and attenuates inflammatory responses in baboons lethally challenged with Escherichia coli

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12 December 2020

Anti-inflammatory, antithrombotic, and neuroprotective effects of activated protein C in a murine model of focal ischemic stroke.

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12 December 2020

The crystal structure of the endothelial protein C receptor and a bound phospholipid

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12 December 2020

Inactivation of the gene for anticoagulant protein C causes lethal perinatal consumptive coagulopathy in mice

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12 December 2020

Complex-dependent inhibition of factor VIIa by antithrombin III and heparin.

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12 December 2020

Gene expression profile of antithrombotic protein c defines new mechanisms modulating inflammation and apoptosis

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12 December 2020

Bench-to-bedside review: functional relationships between coagulation and the innate immune response and their respective roles in the pathogenesis of sepsis

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12 December 2020

Why do animal models (sometimes) fail to mimic human sepsis?

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12 December 2020

The region of the thrombin receptor resembling hirudin binds to thrombin and alters enzyme specificity

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12 December 2020

Antithrombin III stimulates prostacyclin production by cultured aortic endothelial cells

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12 December 2020

CD40L stabilizes arterial thrombi by a β3 integrin–dependent mechanism

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12 December 2020

Intratracheal administration of activated protein C inhibits bleomycin-induced lung fibrosis in the mouse

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12 December 2020

Adhesive receptor Mac-1 coordinates the activation of factor X on stimulated cells of monocytic and myeloid differentiation: an alternative initiation of the coagulation protease cascade

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12 December 2020

Transfer of tissue factor from leukocytes to platelets is mediated by CD15 and tissue factor

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12 December 2020

A targeted point mutation in thrombomodulin generates viable mice with a prethrombotic state

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12 December 2020

Structurally homologous ligand binding of integrin Mac-1 and viral glycoprotein C receptors

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12 December 2020

Plasma thrombomodulin in health and diseases.

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12 December 2020

Transmembrane phospholipid distribution in blood cells: control mechanisms and pathophysiological significance

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12 December 2020

Autoantibodies against EPCR are found in antiphospholipid syndrome and are a risk factor for fetal death.

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12 December 2020

Thrombus formation: direct real-time observation and digital analysis of thrombus assembly in a living mouse by confocal and widefield intravital microscopy.

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12 December 2020

A major outbreak of severe acute respiratory syndrome in Hong Kong

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12 December 2020

Efficacy and safety of recombinant human activated protein C for severe sepsis

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12 December 2020

Identification, cloning, and regulation of a novel endothelial cell protein C/activated protein C receptor

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12 December 2020

Antithrombin III prevents and rapidly reverses leukocyte recruitment in ischemia/reperfusion

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12 December 2020

Activation of endothelial cell protease activated receptor 1 by the protein C pathway

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12 December 2020

Efficacy and safety of tifacogin (recombinant tissue factor pathway inhibitor) in severe sepsis: a randomized controlled trial

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12 December 2020

The molecular basis of blood coagulation

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12 December 2020

Cell mediated events that control blood coagulation and vascular injury

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12 December 2020

Tumor necrosis factor suppresses transcription of the thrombomodulin gene in endothelial cells

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12 December 2020

Activated protein C inhibits lipopolysaccharide-induced nuclear translocation of nuclear factor kappaB (NF-kappaB) and tumour necrosis factor alpha (TNF-alpha) production in the THP-1 monocytic cell line

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12 December 2020

Lipid antigen presentation in the immune system: lessons learned from CD1d knockout mice.

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12 December 2020

The lectin-like domain of thrombomodulin confers protection from neutrophil-mediated tissue damage by suppressing adhesion molecule expression via nuclear factor kappaB and mitogen-activated protein kinase pathways

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12 December 2020

Complete antithrombin deficiency in mice results in embryonic lethality

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12 December 2020

CD40 ligand on activated platelets triggers an inflammatory reaction of endothelial cells

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12 December 2020

A monoclonal antibody against activated protein C allows rapid detection of activated protein C in plasma and reveals a calcium ion dependent epitope involved in factor Va inactivation

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12 December 2020

Caring for the critically ill patient. High-dose antithrombin III in severe sepsis: a randomized controlled trial

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12 December 2020

The participation of leukocytes in coagulant reactions

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12 December 2020

Cytokines, platelet production and hemostasis

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12 December 2020

Disseminated intravascular coagulation

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12 December 2020

Blood-borne tissue factor: another view of thrombosis

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12 December 2020

Assembly of the platelet prothrombinase complex is linked to vesiculation of the platelet plasma membrane. Studies in Scott syndrome: an isolated defect in platelet procoagulant activity

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12 December 2020

Selective cellular expression of tissue factor in human tissues. Implications for disorders of hemostasis and thrombosis.

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12 December 2020

Thrombin Activatable Fibrinolysis Inhibitor, a Potential Regulator of Vascular Inflammation

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12 December 2020

Expression and function of the endothelial protein C receptor in human neutrophils

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12 December 2020

Activated protein C prevents endotoxin-induced hypotension in rats by inhibiting excessive production of nitric oxide

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12 December 2020

Regulation of inflammatory responses by natural anticoagulants

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12 December 2020

Anticoagulantly active heparin-like molecules from vascular tissue

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12 December 2020

Antithrombin inhibits lipopolysaccharide-induced tissue factor and interleukin-6 production by mononuclear cells, human umbilical vein endothelial cells, and whole blood

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12 December 2020

Antithrombin III inhibits nuclear factor kappaB activation in human monocytes and vascular endothelial cells

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12 December 2020

Crystal structures of native and thrombin-complexed heparin cofactor II reveal a multistep allosteric mechanism

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12 December 2020

Disruption of the endothelial cell protein C receptor gene in mice causes placental thrombosis and early embryonic lethality.

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12 December 2020

Treatment of homozygous protein C deficiency and neonatal purpura fulminans with a purified protein C concentrate

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12 December 2020

Carboxypeptidase R is an inactivator of complement-derived inflammatory peptides and an inhibitor of fibrinolysis

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12 December 2020

Elements of the primary structure of thrombomodulin required for efficient thrombin-activable fibrinolysis inhibitor activation

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12 December 2020

Tissue factor pathway inhibitor reduces mortality from Escherichia coli septic shock

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12 December 2020

Alteration in glycosaminoglycan metabolism and surface charge on human umbilical vein endothelial cells induced by cytokines, endotoxin and neutrophils

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12 December 2020

Binding of activated protein C to a specific receptor on human mononuclear phagocytes inhibits intracellular calcium signaling and monocyte-dependent proliferative responses

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12 December 2020

Syndecan-4 as antithrombin receptor of human neutrophils

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12 December 2020

Binding of factor VIIa to tissue factor induces alterations in gene expression in human fibroblast cells: up-regulation of poly(A) polymerase

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12 December 2020

Activated protein C blocks p53-mediated apoptosis in ischemic human brain endothelium and is neuroprotective

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12 December 2020

Activated protein C suppresses tissue factor expression on U937 cells in the endothelial protein C receptor-dependent manner

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12 December 2020

Tissue factor pathway inhibitor gene disruption produces intrauterine lethality in mice.

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12 December 2020

Activated protein C inhibits lipopolysaccharide-induced tumor necrosis factor-alpha production by inhibiting activation of both nuclear factor-kappa B and activator protein-1 in human monocytes.

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12 December 2020

The fifth and sixth growth factor-like domains of thrombomodulin bind to the anion-binding exosite of thrombin and alter its specificity

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12 December 2020

The influence of capsulation and lipooligosaccharide structure on neutrophil adhesion molecule expression and endothelial injury by Neisseria meningitidis

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12 December 2020

Activated protein C cleaves factor Va more efficiently on endothelium than on platelet surfaces

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12 December 2020

Pathophysiologic implications of membrane phospholipid asymmetry in blood cells

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12 December 2020

Identifiers

DOI

10.1016/J.IT.2004.08.003

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10 August 2017

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PubMed ID

15364056