Mechanisms controlling pathogenesis and survival of leukemic stem cells (Q35892084)

11 August 2017

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title

Mechanisms controlling pathogenesis and survival of leukemic stem cells (English)

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11 August 2017

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Craig T Jordan

1

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11 August 2017

Monica L Guzman

series ordinal

2

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11 August 2017

language of work or name

English

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publication date

1 September 2004

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11 August 2017

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11 August 2017

23

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11 August 2017

43

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11 August 2017

7178-7187

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1207935

11 August 2017

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cites work

Somatic activation of oncogenic Kras in hematopoietic cells initiates a rapidly fatal myeloproliferative disorder

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207935

Conditional expression of oncogenic K-ras from its endogenous promoter induces a myeloproliferative disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207935

Molecular genetics of acute myeloid leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207935

A murine model of CML blast crisis induced by cooperation between BCR/ABL and NUP98/HOXA9

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207935

Inhibition of both paracrine and autocrine VEGF/ VEGFR-2 signaling pathways is essential to induce long-term remission of xenotransplanted human leukemias

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207935

Clonal origin of chronic myelocytic leukemia in man

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207935

Chronic myelocytic leukemia: Clonal origin in a stem cell common to the granulocyte, erythrocyte, platelet and monocyte/macrophage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207935

Preferential induction of apoptosis for primary human leukemic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207935

NF-kappa B as a therapeutic target in multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207935

The P190, P210, and P230 forms of the BCR/ABL oncogene induce a similar chronic myeloid leukemia-like syndrome in mice but have different lymphoid leukemogenic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207935

21 January 2018

Acute myeloid leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207935

Prospective isolation of human clonogenic common myeloid progenitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207935

Normal and leukemic hematopoiesis: Are leukemias a stem cell disorder or a reacquisition of stem cell characteristics?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207935

Cellular signalling pathways: new targets in leukaemia therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207935

Fatal myeloproliferation, induced in mice by TEL/PDGFbetaR expression, depends on PDGFbetaR tyrosines 579/581

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207935

AML1-ETO expression is directly involved in the development of acute myeloid leukemia in the presence of additional mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207935

A clonogenic common myeloid progenitor that gives rise to all myeloid lineages

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207935

7 January 2021

Constitutive NF-κB DNA-binding activity in AML is frequently mediated by a Ras/PI3-K/PKB-dependent pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207935

7 January 2021

A Quantitative Assay for the Number of Murine Lymphoma Cells capable of Proliferation in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207935

7 January 2021

Expression and activity of P-glycoprotein, a multidrug efflux pump, in human hematopoietic stem cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207935

7 January 2021

Cooperation of BCR-ABL and AML1/MDS1/EVI1 in blocking myeloid differentiation and rapid induction of an acute myelogenous leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207935

7 January 2021

The roles of FLT3 in hematopoiesis and leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207935

7 January 2021

Molecular classification of cancer: class discovery and class prediction by gene expression monitoring

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207935

7 January 2021

Primitive, quiescent, Philadelphia-positive stem cells from patients with chronic myeloid leukemia are insensitive to STI571 in vitro

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207935

7 January 2021

Detection, isolation, and stimulation of quiescent primitive leukemic progenitor cells from patients with acute myeloid leukemia (AML).

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207935

7 January 2021

Nuclear factor-kappaB is constitutively activated in primitive human acute myelogenous leukemia cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207935

7 January 2021

Expression of tumor-suppressor genes interferon regulatory factor 1 and death-associated protein kinase in primitive acute myelogenous leukemia cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207935

7 January 2021

Elucidating critical mechanisms of deregulated stem cell turnover in the chronic phase of chronic myeloid leukemia.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207935

7 January 2021

The interleukin-3 receptor alpha chain is a unique marker for human acute myelogenous leukemia stem cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207935

7 January 2021

FLT3 internal tandem duplication mutations associated with human acute myeloid leukemias induce myeloproliferative disease in a murine bone marrow transplant model

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207935

7 January 2021

A cell initiating human acute myeloid leukaemia after transplantation into SCID mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207935

7 January 2021

Signaling pathways activated by daunorubicin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207935

7 January 2021

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207935

7 January 2021

Retrovirus-mediated gene transfer of MLL-ELL transforms primary myeloid progenitors and causes acute myeloid leukemias in mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207935

7 January 2021

Microenvironmental regulation of hematopoietic stem cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207935

7 January 2021

Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207935

7 January 2021

Interleukin 3 and granulocyte-macrophage colony-stimulating factor are not required for induction of chronic myeloid leukemia-like myeloproliferative disease in mice by BCR/ABL.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207935

7 January 2021

Oncogenic interaction between BCR-ABL and NUP98-HOXA9 demonstrated by the use of an in vitro purging culture system.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207935

7 January 2021

The AML1-ETO fusion protein promotes the expansion of human hematopoietic stem cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207935

7 January 2021

Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207935

7 January 2021

Stem cells, cancer, and cancer stem cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207935

7 January 2021

Anti-cancer alkyl-lysophospholipids inhibit the phosphatidylinositol 3-kinase-Akt/PKB survival pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207935

7 January 2021

JAK/STAT, Raf/MEK/ERK, PI3K/Akt and BCR-ABL in cell cycle progression and leukemogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207935

7 January 2021

FLT3, RAS, and TP53 mutations in elderly patients with acute myeloid leukemia.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207935

7 January 2021

Endothelial cell activation by myeloblasts: molecular mechanisms of leukostasis and leukemic cell dissemination

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207935

7 January 2021

Acute promyelocytic leukemia: evolving therapeutic strategies

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207935

7 January 2021

p53 stabilization is decreased upon NFkappaB activation: a role for NFkappaB in acquisition of resistance to chemotherapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207935

7 January 2021

Interleukin-3 receptor in acute leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207935

7 January 2021

Induction of myeloproliferative disease in mice by tyrosine kinase fusion oncogenes does not require granulocyte-macrophage colony-stimulating factor or interleukin-3.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207935

7 January 2021

NF-kappaB/Rel-mediated regulation of apoptosis in hematologic malignancies and normal hematopoietic progenitors.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207935

7 January 2021

Survival of acute myeloid leukemia cells requires PI3 kinase activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207935

7 January 2021

A model of human p210(bcr/ABL)-mediated chronic myelogenous leukemia by transduction of primary normal human CD34(+) cells with a BCR/ABL-containing retroviral vector

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207935

7 January 2021

Inhibition of phosphatidylinositol 3-kinase dephosphorylates BAD and promotes apoptosis in myeloid leukemias

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207935

7 January 2021

Inhibition of human leukemia in an animal model with human antibodies directed against vascular endothelial growth factor receptor 2. Correlation between antibody affinity and biological activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207935

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1207935

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Dimensions Publication ID

11 August 2017

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1 reference