Emerging role for ERK as a key regulator of neuronal apoptosis (Q35895210)

11 August 2017

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title

Emerging role for ERK as a key regulator of neuronal apoptosis (English)

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11 August 2017

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Eric C C Cheung

1

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PubMed ID

15383672

11 August 2017

Ruth S Slack

series ordinal

2

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11 August 2017

14 September 2004

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Science's STKE : signal transduction knowledge environment

11 August 2017

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11 August 2017

2004

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11 August 2017

251

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11 August 2017

PE45

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Mitogen-activated protein kinases in apoptosis regulation

11 August 2017

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2512004PE45

Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2512004PE45

ERK activation promotes neuronal degeneration predominantly through plasma membrane damage and independently of caspase-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2512004PE45

Chronic activation of ERK and neurodegenerative diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2512004PE45

ERK and p38 MAPK-activated protein kinases: a family of protein kinases with diverse biological functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2512004PE45

Signaling pathways for PC12 cell differentiation: making the right connections

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2512004PE45

Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2512004PE45

A critical role of neural-specific JNK3 for ischemic apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2512004PE45

Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2512004PE45

The Bax subfamily of Bcl2-related proteins is essential for apoptotic signal transduction by c-Jun NH(2)-terminal kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2512004PE45

Peroxynitrite induces GADD34, 45, and 153 VIA p38 MAPK in human neuroblastoma SH-SY5Y cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2512004PE45

Mitogen-activated protein kinases in synaptic plasticity and memory.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2512004PE45

Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2512004PE45

Inhibition of caspase-9 through phosphorylation at Thr 125 by ERK MAPK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2512004PE45

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2512004PE45

B-Raf inhibits programmed cell death downstream of cytochrome c release from mitochondria by activating the MEK/Erk pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2512004PE45

The p42/p44 MAP kinase pathway prevents apoptosis induced by anchorage and serum removal

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2512004PE45

The cellular response to oxidative stress: influences of mitogen-activated protein kinase signalling pathways on cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2512004PE45

Oxidative neuronal injury. The dark side of ERK1/2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2512004PE45

Sustained extracellular signal-regulated kinase activation by 6-hydroxydopamine: implications for Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2512004PE45

Cytoplasmic aggregates of phosphorylated extracellular signal-regulated protein kinases in Lewy body diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2512004PE45

Persistent activation of ERK contributes to glutamate-induced oxidative toxicity in a neuronal cell line and primary cortical neuron cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2512004PE45

MEK1 protein kinase inhibition protects against damage resulting from focal cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2512004PE45

Intravenous administration of MEK inhibitor U0126 affords brain protection against forebrain ischemia and focal cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2512004PE45

Up-regulation of mitogen-activated protein kinases ERK1/2 and MEK1/2 is associated with the progression of neurofibrillary degeneration in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2512004PE45

Induction of apoptosis in cerebellar granule neurons by low potassium: inhibition of death by insulin-like growth factor I and cAMP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2512004PE45

Growth differentiation factor-15 prevents low potassium-induced cell death of cerebellar granule neurons by differential regulation of Akt and ERK pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2512004PE45

Mitogen-activated protein kinases: specific messages from ubiquitous messengers

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2512004PE45

CNK2 couples NGF signal propagation to multiple regulatory cascades driving cell differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2512004PE45

Molecular characterization of mitochondrial apoptosis-inducing factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2512004PE45

Role of AIF in caspase-dependent and caspase-independent cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2512004PE45

Apoptosis-inducing factor is involved in the regulation of caspase-independent neuronal cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2512004PE45

Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2512004PE45

Nuclear and mitochondrial conversations in cell death: PARP-1 and AIF signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2512004PE45

Endonuclease G is an apoptotic DNase when released from mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2512004PE45

Mechanisms of AIF-mediated apoptotic DNA degradation in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2512004PE45

Distribution, levels, and activation of MEK1 in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2512004PE45

21 January 2018

Identifiers

DOI

10.1126/STKE.2512004PE45

1 reference

11 August 2017

1 reference

PubMed ID

15383672