Epigenetic modifications in cardiovascular disease. (Q35898458)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22234702%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

1 reference

25 September 2020

Epigenetic modifications in cardiovascular disease (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22234702%20AND%20SRC:MED&resulttype=core&format=json

regulation of gene expression

20 January 2020

main subject

cardiovascular disease

3 references

17 June 2019

8 September 2019

25 September 2020

1 reference

8 September 2019

1 reference

1 reference

25 September 2020

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22234702%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

author name string

Johan M Lorenzen

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22234702%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Filippo Martino

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22234702%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

publication date

11 January 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22234702%20AND%20SRC:MED&resulttype=core&format=json

Basic Research in Cardiology

20 January 2020

1 March 2012

1 reference

25 September 2020

4 references

17 June 2019

8 September 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22234702%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

25 September 2020

107

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22234702%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22234702%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

page(s)

245

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22234702%20AND%20SRC:MED&resulttype=core&format=json

Distinct epigenomic features in end-stage failing human hearts

20 January 2020

cites work

1 reference

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Histone deacetylase 3 regulates smooth muscle differentiation in neural crest cells and development of the cardiac outflow tract

11 July 2018

1 reference

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DNA demethylation dynamics

11 July 2018

1 reference

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MicroRNAs and vascular (dys)function.

11 July 2018

1 reference

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Biogenesis and regulation of cardiovascular microRNAs.

11 July 2018

1 reference

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Depletion of Kcnq1ot1 non-coding RNA does not affect imprinting maintenance in stem cells

11 July 2018

1 reference

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Caveolin induces cardioprotection through epigenetic regulation

11 July 2018

1 reference

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Loss of H3K4 methylation destabilizes gene expression patterns and physiological functions in adult murine cardiomyocytes.

11 July 2018

1 reference

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CpG islands and the regulation of transcription

11 July 2018

1 reference

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Non-coding RNAs as regulators of gene expression and epigenetics.

11 July 2018

1 reference

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The histone trimethyllysine demethylase JMJD2A promotes cardiac hypertrophy in response to hypertrophic stimuli in mice

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329881

Biological functions of methyl-CpG-binding proteins

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329881

Control of cardiovascular differentiation by microRNAs

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329881

Chromatin remodeling pathways in smooth muscle cell differentiation, and evidence for an integral role for p300.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329881

FSHD: a repeat contraction disease finally ready to expand (our understanding of its pathogenesis)

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329881

Large non-coding RNAs: missing links in cancer?

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329881

Mammalian microRNAs predominantly act to decrease target mRNA levels

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329881

Epigenetic silencing of miR-137 is an early event in colorectal carcinogenesis

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329881

Molecular interplay of the noncoding RNA ANRIL and methylated histone H3 lysine 27 by polycomb CBX7 in transcriptional silencing of INK4a

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329881

Chronic prenatal hypoxia induces epigenetic programming of PKC{epsilon} gene repression in rat hearts

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329881

Histone deacetylase 7 controls endothelial cell growth through modulation of beta-catenin

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329881

Differential DNA methylation correlates with differential expression of angiogenic factors in human heart failure

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329881

A noncoding antisense RNA in tie-1 locus regulates tie-1 function in vivo

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329881

Prenatal tobacco smoke exposure affects global and gene-specific DNA methylation

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329881

Evolution and functions of long noncoding RNAs

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329881

MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329881

The Air noncoding RNA epigenetically silences transcription by targeting G9a to chromatin

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329881

Polycomb proteins targeted by a short repeat RNA to the mouse X chromosome

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329881

Persistent epigenetic differences associated with prenatal exposure to famine in humans

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329881

Cardiac-specific overexpression of caveolin-3 induces endogenous cardiac protection by mimicking ischemic preconditioning

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329881

Dysregulation of microRNAs after myocardial infarction reveals a role of miR-29 in cardiac fibrosis

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329881

Role of microRNAs in vascular diseases, inflammation, and angiogenesis

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329881

Epigenetic silencing of tumour suppressor gene p15 by its antisense RNA

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329881

Susceptibility to coronary artery disease and diabetes is encoded by distinct, tightly linked SNPs in the ANRIL locus on chromosome 9p.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329881

Reactivation of epigenetically silenced genes by DNA methyltransferase inhibitors: basic concepts and clinical applications

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329881

DUX4, a candidate gene of facioscapulohumeral muscular dystrophy, encodes a transcriptional activator of PITX1

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329881

Ultraconserved regions encoding ncRNAs are altered in human leukemias and carcinomas

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329881

MicroRNAs in the human heart: a clue to fetal gene reprogramming in heart failure

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329881

Programming smooth muscle plasticity with chromatin dynamics

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329881

Perceptions of epigenetics

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329881

A common variant on chromosome 9p21 affects the risk of myocardial infarction

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329881

Characterization of a germ-line deletion, including the entire INK4/ARF locus, in a melanoma-neural system tumor family: identification of ANRIL, an antisense noncoding RNA whose expression coclusters with ARF.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329881

Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329881

Chromatin modifications and their function

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329881

Epigenetic modification of the renin-angiotensin system in the fetal programming of hypertension

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329881

Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329881

Control of translation and mRNA degradation by miRNAs and siRNAs

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329881

A genome-wide analysis of CpG dinucleotides in the human genome distinguishes two distinct classes of promoters

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329881

Prenatal exposure to the Dutch famine and disease in later life: an overview

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329881

The Microprocessor complex mediates the genesis of microRNAs

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329881

Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329881

The ENCODE (ENCyclopedia Of DNA Elements) Project

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329881

MicroRNA genes are transcribed by RNA polymerase II

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329881

The functions of animal microRNAs

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329881

MicroRNAs: genomics, biogenesis, mechanism, and function

11 July 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329881

11 July 2018

https://api.crossref.org/works/10.1007%2FS00395-012-0245-9

Opposing roles of delta and epsilonPKC in cardiac ischemia and reperfusion: targeting the apoptotic machinery

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329881

Preservation of base-line hemodynamic function and loss of inducible cardioprotection in adult mice lacking protein kinase C epsilon

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329881

The nuclear RNase III Drosha initiates microRNA processing

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329881

The power and the promise of DNA methylation markers

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329881

Active genes are tri-methylated at K4 of histone H3

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329881

Comprehensive analysis of CpG islands in human chromosomes 21 and 22

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329881

Fetal programming and adult health

11 July 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329881

11 July 2018

https://api.crossref.org/works/10.1007%2FS00395-012-0245-9

Opposing cardioprotective actions and parallel hypertrophic effects of delta PKC and epsilon PKC.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329881

aHIF: a natural antisense transcript overexpressed in human renal cancer and during hypoxia

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329881

Transcription of IAP endogenous retroviruses is constrained by cytosine methylation

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329881

DNA hypomethylation can activate Xist expression and silence X-linked genes.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329881

The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329881

Role for DNA methylation in genomic imprinting

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329881

DNA methylation and the frequency of CpG in animal DNA.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329881

CpG islands in vertebrate genomes

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329881

CpG-rich islands and the function of DNA methylation

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329881

Tissue-specific differences in DNA methylation in various mammals

11 July 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00395-012-0245-9

Genome-wide histone methylation profile for heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00395-012-0245-9

Correlation between histone lysine methylation and developmental changes at the chicken beta-globin locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00395-012-0245-9

MicroRNA signatures in total peripheral blood as novel biomarkers for acute myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00395-012-0245-9

Histone deacetylase 7 silencing alters endothelial cell migration, a key step in angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00395-012-0245-9

Post-transcriptional regulation of endothelial nitric-oxide synthase by an overlapping antisense mRNA transcript

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00395-012-0245-9

Maternal cocaine administration causes an epigenetic modification of protein kinase Cepsilon gene expression in fetal rat heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00395-012-0245-9

Epigenetic regulation of endothelial lineage committed genes in pro-angiogenic hematopoietic and endothelial progenitor cells

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329881

Long noncoding RNA high expression in hepatocellular carcinoma facilitates tumor growth through enhancer of zeste homolog 2 in humans

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329881

Cardiac ventricular chambers are epigenetically distinguishable

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329881

Shear stress-mediated chromatin remodeling provides molecular basis for flow-dependent regulation of gene expression.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329881

The same sequence variant on 9p21 associates with myocardial infarction, abdominal aortic aneurysm and intracranial aneurysm

24 September 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00395-012-0245-9

Cardioprotection: nitric oxide, protein kinases, and mitochondria

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22234702

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

RNA silencing: Mechanism, biology and responses to environmental stress

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22234702

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1007/S00395-012-0245-9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22234702%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22234702%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

PubMed publication ID

22234702

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22234702%20AND%20SRC:MED&resulttype=core&format=json