Cyclooxygenase-2 (COX-2) in inflammatory and degenerative brain diseases (Q35903755)

11 August 2017

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title

Cyclooxygenase-2 (COX-2) in inflammatory and degenerative brain diseases (English)

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11 August 2017

Luisa Minghetti

1

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PubMed ID

15453089

11 August 2017

language of work or name

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1 September 2004

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Journal of Neuropathology & Experimental Neurology

11 August 2017

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11 August 2017

63

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11 August 2017

901-910

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11 August 2017

9

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Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs

11 August 2017

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.9.901

Prostaglandin endoperoxide H synthases (cyclooxygenases)-1 and -2

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.9.901

Cyclooxygenase-2--10 years later

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.9.901

Structural basis for selective inhibition of cyclooxygenase-2 by anti-inflammatory agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.9.901

Expression of a mitogen-inducible cyclooxygenase in brain neurons: regulation by synaptic activity and glucocorticoids

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.9.901

Characterization of inducible cyclooxygenase in rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.9.901

Expression of mRNA for cyclooxygenase-1 and cyclooxygenase-2 in human tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.9.901

Distribution of cyclooxygenase-1 and cyclooxygenase-2 mRNAs and proteins in human brain and peripheral organs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.9.901

Cyclooxygenases in central nervous system diseases: a special role for cyclooxygenase 2 in neuronal cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.9.901

Cyclooxygenases and central nervous system inflammation: conceptual neglect of cyclooxygenase 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.9.901

COX-3, a cyclooxygenase-1 variant inhibited by acetaminophen and other analgesic/antipyretic drugs: cloning, structure, and expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.9.901

COX-3: a splice variant of cyclooxygenase-1 in mouse neural tissue and cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.9.901

Cyclooxygenases and the central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.9.901

Microglia as effector cells in brain damage and repair: focus on prostanoids and nitric oxide

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.9.901

COX-2, a synaptically induced enzyme, is expressed by excitatory neurons at postsynaptic sites in rat cerebral cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.9.901

Cyclooxygenase-2 expression during rat neocortical development and in Rett syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.9.901

Cognitive and neurological deficits induced by early and prolonged basal forebrain cholinergic hypofunction in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.9.901

Post-training cyclooxygenase-2 (COX-2) inhibition impairs memory consolidation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.9.901

Inhibitors of cyclooxygenases produce amnesia for a passive avoidance task in the chick.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.9.901

Intrahippocampal infusion of a cyclooxygenase-2 inhibitor attenuates memory acquisition in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.9.901

Deficits in spatial learning and synaptic plasticity induced by the rapid and competitive broad-spectrum cyclooxygenase inhibitor ibuprofen are reversed by increasing endogenous brain-derived neurotrophic factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.9.901

Synaptic lipid signaling: significance of polyunsaturated fatty acids and platelet-activating factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.9.901

Renal abnormalities and an altered inflammatory response in mice lacking cyclooxygenase II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.9.901

Inflammation in multiple sclerosis: the good, the bad, and the complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.9.901

The link between excitotoxic oligodendroglial death and demyelinating diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.9.901

21 January 2018

Glia-T cell dialogue.

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.9.901

Cyclooxygenases-1 and -2 are differentially localized to microglia and endothelium in rat EAE and glioma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.9.901

Restricted cyclooxygenase-2 expression in the central nervous system following acute and delayed-type hypersensitivity responses to bacillus Calmette-Guérin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.9.901

Inflammatory cell expression of cyclooxygenase-2 in the multiple sclerosis lesion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.9.901

Prostaglandins stimulate calcium-dependent glutamate release in astrocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.9.901

Peroxynitrite inhibits glutamate transporter subtypes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.9.901

Prostaglandins as modulators of immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.9.901

Potential role of prostaglandins and leukotrienes in multiple sclerosis and experimental allergic encephalomyelitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.9.901

Neuroinflammation, COX-2, and ALS--a dual role?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.9.901

Marked increase in cyclooxygenase-2 in ALS spinal cord: implications for therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.9.901

Increased expression of the pro-inflammatory enzyme cyclooxygenase-2 in amyotrophic lateral sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.9.901

Increased levels of the pro-inflammatory prostaglandin PGE2 in CSF from ALS patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.9.901

Expression and localization of cyclooxygenase‐1 and ‐2 in human sporadic amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.9.901

Cyclooxygenase 2 inhibition protects motor neurons and prolongs survival in a transgenic mouse model of ALS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.9.901

15-Deoxy-Delta(12,14)-prostaglandin J(2): the endogenous electrophile that induces neuronal apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.9.901

Novel anti-inflammatory therapy for Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.9.901

Non-steroidal anti-inflammatory drug sodium salicylate, but not diclofenac or celecoxib, protects against 1-methyl-4-phenyl pyridinium-induced dopaminergic neurotoxicity in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.9.901

Cyclooxygenase-2 is instrumental in Parkinson's disease neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.9.901

Inflammatory regulators in Parkinson's disease: iNOS, lipocortin-1, and cyclooxygenases-1 and -2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.9.901

The impact of systemic infection on the progression of neurodegenerative disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.9.901

Cyclooxygenase-1 and -2 in brains of patients who died with sporadic Creutzfeldt-Jakob disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.9.901

Increased CSF levels of prostaglandin E(2) in variant Creutzfeldt-Jakob disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.9.901

Neuronal apoptosis in Creutzfeldt-Jakob disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.9.901

Atypical antiinflammatory activation of microglia induced by apoptotic neurons: possible role of phosphatidylserine-phosphatidylserine receptor interaction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.9.901

Cyclo-oxygenase inhibitors protect against prion-induced neurotoxicity in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.9.901

The potential of anti-inflammatory drugs for the treatment of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.9.901

Prostaglandin G/H synthase-2 (cyclooxygenase-2) mRNA expression is decreased in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.9.901

Cyclooxygenase-2 expression is increased in frontal cortex of Alzheimer's disease brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.9.901

Cyclooxygenase 2 RNA message abundance, stability, and hypervariability in sporadic Alzheimer neocortex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.9.901

Cyclin D1 and cyclin E are co-localized with cyclo-oxygenase 2 (COX-2) in pyramidal neurons in Alzheimer disease temporal cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.9.901

Neuronal COX-2 expression and phosphorylation of pRb precede p38 MAPK activation and neurofibrillary changes in AD temporal cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.9.901

The cell division cycle and the pathophysiology of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.9.901

Cyclooxygenase-1 in human Alzheimer and control brain: quantitative analysis of expression by microglia and CA3 hippocampal neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.9.901

21 January 2018

Identifiers

DOI

10.1093/JNEN/63.9.901

1 reference

11 August 2017

1 reference

PubMed ID

15453089