Adiponectin associates with markers of cartilage degradation in osteoarthritis and induces production of proinflammatory and catabolic factors through mitogen-activated protein kinase pathways. (Q35907720)

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scientific article published on 11 November 2011

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English	Adiponectin associates with markers of cartilage degradation in osteoarthritis and induces production of proinflammatory and catabolic factors through mitogen-activated protein kinase pathways.	scientific article published on 11 November 2011

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scholarly article

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16 January 2020

Adiponectin associates with markers of cartilage degradation in osteoarthritis and induces production of proinflammatory and catabolic factors through mitogen-activated protein kinase pathways (English)

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16 January 2020

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Katriina Vuolteenaho

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16 January 2020

author name string

Anna Koskinen

1

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16 January 2020

Sami Juslin

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16 January 2020

Riina Nieminen

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16 January 2020

Teemu Moilanen

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16 January 2020

Eeva Moilanen

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16 January 2020

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11 November 2011

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16 January 2020

Arthritis Research and Therapy

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16 January 2020

13

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16 January 2020

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16 January 2020

R184

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16 January 2020

https://scigraph.springernature.com/pub.10.1186/ar3512

0 references

What's new in our understanding of the role of adipokines in rheumatic diseases?

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11 July 2018

Cardiometabolic comorbidities and rheumatic diseases: focus on the role of fat mass and adipokines.

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11 July 2018

Application of biomarkers in the development of drugs intended for the treatment of osteoarthritis

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11 July 2018

Adipocytokines as driving forces in rheumatoid arthritis and related inflammatory diseases?

1 reference

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11 July 2018

Adipokines in inflammation and metabolic disease

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11 July 2018

Adiponectin is a potential catabolic mediator in osteoarthritis cartilage

1 reference

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11 July 2018

Adiponectin action from head to toe.

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11 July 2018

Adiponectin may contribute to synovitis and joint destruction in rheumatoid arthritis by stimulating vascular endothelial growth factor, matrix metalloproteinase-1, and matrix metalloproteinase-13 expression in fibroblast-like synoviocytes more than

1 reference

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11 July 2018

Adiponectin is a mediator of the inverse association of adiposity with radiographic damage in rheumatoid arthritis

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11 July 2018

Leptin enhances synthesis of proinflammatory mediators in human osteoarthritic cartilage--mediator role of NO in leptin-induced PGE2, IL-6, and IL-8 production

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11 July 2018

Adiponectin-stimulated CXCL8 release in primary human hepatocytes is regulated by ERK1/ERK2, p38 MAPK, NF-kappaB, and STAT3 signaling pathways

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11 July 2018

Adiponectin, an unlocking adipocytokine

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11 July 2018

Mitogen-activated protein kinases as therapeutic targets in osteoarthritis

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11 July 2018

A new player in cartilage homeostasis: adiponectin induces nitric oxide synthase type II and pro-inflammatory cytokines in chondrocytes.

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11 July 2018

Phosphatidylinositol 3-kinase, MEK-1 and p38 mediate leptin/interferon-gamma synergistic NOS type II induction in chondrocytes.

1 reference

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11 July 2018

The role of nitric oxide in osteoarthritis

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11 July 2018

Post-transcriptional regulation of human inducible nitric-oxide synthase expression by the Jun N-terminal kinase.

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11 July 2018

Inflammatory signaling in cartilage: MAPK and NF-kappaB pathways in chondrocytes and the use of inhibitors for research into pathogenesis and therapy of osteoarthritis

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11 July 2018

Adipocytokines: mediators linking adipose tissue, inflammation and immunity

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11 July 2018

Understanding the role of tissue degrading enzymes and their inhibitors in development and disease

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11 July 2018

Inhibition of p38 mitogen-activated protein kinase enhances c-Jun N-terminal kinase activity: implication in inducible nitric oxide synthase expression

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11 July 2018

TGFbeta inhibits IL-1 -induced iNOS expression and NO production in immortalized chondrocytes

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11 July 2018

Inhibitors of mitogen-activated protein kinases downregulate COX-2 expression in human chondrocytes

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11 July 2018

Signalling pathway involved in nitric oxide synthase type II activation in chondrocytes: synergistic effect of leptin with interleukin-1

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11 July 2018

Novel inhibitors of matrix metalloproteinase gene expression as potential therapies for arthritis

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11 July 2018

Synergistic induction of nitric oxide synthase type II: in vitro effect of leptin and interferon-gamma in human chondrocytes and ATDC5 chondrogenic cells

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11 July 2018

ACRP30, a new hormone controlling fat and glucose metabolism

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11 July 2018

Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muscle and causes weight loss in mice

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11 July 2018

Reduced progression of experimental osteoarthritis in vivo by selective inhibition of inducible nitric oxide synthase.

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11 July 2018

Cartilage markers in synovial fluid in symptomatic knee osteoarthritis.

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11 July 2018

Nitric oxide production and inducible nitric oxide synthase expression in inflammatory arthritides

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11 July 2018

A novel serum protein similar to C1q, produced exclusively in adipocytes

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Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids

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11 July 2018

Development of criteria for the classification and reporting of osteoarthritis. Classification of osteoarthritis of the knee. Diagnostic and Therapeutic Criteria Committee of the American Rheumatism Association

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11 July 2018

Association between leptin, adiponectin and resistin and long-term progression of hand osteoarthritis.

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24 September 2018

Leptin enhances MMP-1, MMP-3 and MMP-13 production in human osteoarthritic cartilage and correlates with MMP-1 and MMP-3 in synovial fluid from OA patients.

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24 September 2018

Adiponectin increases MMP-3 expression in human chondrocytes through AdipoR1 signaling pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334633

24 September 2018

Synovial fluid level of adiponectin correlated with levels of aggrecan degradation markers in osteoarthritis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334633

24 September 2018

Adiponectin mitigates the severity of arthritis in mice with collagen-induced arthritis

1 reference

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24 September 2018

Selective iNOS inhibitor 1400W enhances anti-catabolic IL-10 and reduces destructive MMP-10 in OA cartilage. Survey of the effects of 1400W on inflammatory mediators produced by OA cartilage as detected by protein antibody array.

1 reference

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24 September 2018

High adiponectin and adiponectin receptor 1 expression in synovial fluids and synovial tissues of patients with rheumatoid arthritis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334633

24 September 2018

Differential distribution of adipokines between serum and synovial fluid in patients with osteoarthritis. Contribution of joint tissues to their articular production.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334633

24 September 2018

Plasma Adiponectin in Patients with Active, Early, and Chronic Rheumatoid Arthritis Who Are Steroid- and Disease-Modifying Antirheumatic Drug-Naive Compared with Patients with Osteoarthritis and Controls

1 reference

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21 January 2018

Baseline serum adipokine levels predict radiographic progression in early rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1186%2FAR3512

21 January 2018

Adiponectin activates c-Jun NH2-terminal kinase and inhibits signal transducer and activator of transcription 3

1 reference

https://pubmed.ncbi.nlm.nih.gov/22077999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adiponectin enhances IL-6 production in human synovial fibroblast via an AdipoR1 receptor, AMPK, p38, and NF-kappa B pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/22077999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The potential of adiponectin in driving arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22077999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Use of the plasma stromelysin (matrix metalloproteinase 3) concentration to predict joint space narrowing in knee osteoarthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22077999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for a protective role for adiponectin in osteoarthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22077999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased adiponectin is negatively linked to the local inflammatory process in patients with rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22077999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serum cartilage oligomeric matrix protein reflects osteoarthritis presence and severity: The Johnston county osteoarthritis project

1 reference

https://pubmed.ncbi.nlm.nih.gov/22077999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-6 and interleukin-8 levels in serum and synovial fluid of patients with osteoarthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22077999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Osteoarthritis or osteoarthrosis: the definition of inflammation becomes a semantic issue in the genomic era of molecular medicine

1 reference

https://pubmed.ncbi.nlm.nih.gov/22077999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adipocytokines in synovial fluid

1 reference

https://pubmed.ncbi.nlm.nih.gov/22077999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Osteoarthrosis of the knee. A radiographic investigation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22077999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serum adiponectin concentrations correlate with severity of rheumatoid arthritis evaluated by extent of joint destruction.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22077999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlation of plasma and synovial fluid adiponectin with knee osteoarthritis severity

1 reference

https://pubmed.ncbi.nlm.nih.gov/22077999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adiponectin and leptin increase IL-8 production in human chondrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22077999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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16 January 2020

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22077999%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22077999%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

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