NOD2 mutations and Crohn's disease: are Paneth cells and their antimicrobial peptides the link? (Q35915900)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15479670%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

review article

1 reference

title

NOD2 mutations and Crohn's disease: are Paneth cells and their antimicrobial peptides the link? (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15479670%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

main subject

Crohn's disease

0 references

antimicrobial peptide

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15479670%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

author name string

Pavli P

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15479670%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

language of work or name

English

0 references

publication date

1 November 2004

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15479670%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15479670%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

volume

53

1 reference

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4 January 2020

issue

11

1 reference

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4 January 2020

page(s)

1558-1560

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NOD2 (CARD15) mutations in Crohn's disease are associated with diminished mucosal alpha-defensin expression

4 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774293

α-Defensins in the gastrointestinal tract

11 July 2018

1 reference

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Expression and regulation of antimicrobial peptides in the gastrointestinal tract

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774293

Defensins: antimicrobial peptides of innate immunity

11 July 2018

1 reference

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Crohn's disease and the NOD2 gene: a role for paneth cells

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774293

CARD15/NOD2 functions as an antibacterial factor in human intestinal epithelial cells

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774293

Protection against enteric salmonellosis in transgenic mice expressing a human intestinal defensin

11 July 2018

1 reference

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Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774293

Host recognition of bacterial muramyl dipeptide mediated through NOD2. Implications for Crohn's disease

11 July 2018

1 reference

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The contribution of NOD2 gene mutations to the risk and site of disease in inflammatory bowel disease

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774293

The molecular classification of the clinical manifestations of Crohn's disease

11 July 2018

1 reference

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CARD15/NOD2 mutational analysis and genotype-phenotype correlation in 612 patients with inflammatory bowel disease

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774293

A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

11 July 2018

1 reference

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Secretion of microbicidal alpha-defensins by intestinal Paneth cells in response to bacteria

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774293

Evolutionary diversification of the mammalian defensins

11 July 2018

1 reference

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Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-kappaB

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774293

Human neutrophil defensins selectively chemoattract naive T and immature dendritic cells

11 July 2018

1 reference

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Expression and regulation of the human beta-defensins hBD-1 and hBD-2 in intestinal epithelium.

11 July 2018

1 reference

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Mechanisms for induction of acquired host immunity by neutrophil peptide defensins

11 July 2018

1 reference

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Mapping of a susceptibility locus for Crohn's disease on chromosome 16

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774293

Defensins act as potent adjuvants that promote cellular and humoral immune responses in mice to a lymphoma idiotype and carrier antigens

11 July 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15479670

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Examining the role of Paneth cells in the small intestine by lineage ablation in transgenic mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15479670

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1136/GUT.2004.043307

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15479670%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15479670%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

1 reference