Prime suspect: the TCF7L2 gene and type 2 diabetes risk (Q35916130)

11 August 2017

Prime suspect: the TCF7L2 gene and type 2 diabetes risk (English)

1 reference

11 August 2017

1 reference

Andrew Tym Hattersley

series ordinal

1

object named as

Andrew T Hattersley

1 reference

11 August 2017

PMCID

1934573

language of work or name

English

0 references

publication date

1 August 2007

1 reference

Journal of Clinical Investigation

11 August 2017

1 reference

11 August 2017

117

1 reference

11 August 2017

8

1 reference

11 August 2017

2077-2079

1 reference

Mechanisms by which common variants in the TCF7L2 gene increase risk of type 2 diabetes

11 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1934573

Type 2 diabetes TCF7L2 risk genotypes alter birth weight: a study of 24,053 individuals

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1934573

Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1934573

A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1934573

Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1934573

A variant in CDKAL1 influences insulin response and risk of type 2 diabetes

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1934573

TCF7L2 polymorphisms modulate proinsulin levels and beta-cell function in a British Europid population

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1934573

A genome-wide association study identifies novel risk loci for type 2 diabetes

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1934573

TCF7L2: the biggest story in diabetes genetics since HLA?

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1934573

TCF7L2 polymorphisms and progression to diabetes in the Diabetes Prevention Program

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1934573

Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1934573

Activating mutations in the gene encoding the ATP-sensitive potassium-channel subunit Kir6.2 and permanent neonatal diabetes

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1934573

RyR2 and calpain-10 delineate a novel apoptosis pathway in pancreatic islets

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1934573

Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1934573

The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1934573

Dominant negative mutations in human PPARgamma associated with severe insulin resistance, diabetes mellitus and hypertension

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1934573

Common variants in the TCF7L2 gene are strongly associated with type 2 diabetes mellitus in the Indian population.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1934573

Meta-analysis and a large association study confirm a role for calpain-10 variation in type 2 diabetes susceptibility

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1934573

Large-scale association studies of variants in genes encoding the pancreatic beta-cell KATP channel subunits Kir6.2 (KCNJ11) and SUR1 (ABCC8) confirm that the KCNJ11 E23K variant is associated with type 2 diabetes

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1934573

A genetic variation of the transcription factor 7-like 2 gene is associated with risk of type 2 diabetes in the Japanese population

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1934573

Association of the calpain-10 gene with type 2 diabetes in Europeans: Results of pooled and meta-analyses

14 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1934573

Refining the impact of TCF7L2 gene variants on type 2 diabetes and adaptive evolution

14 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1934573

Common single nucleotide polymorphisms in TCF7L2 are reproducibly associated with type 2 diabetes and reduce the insulin response to glucose in nondiabetic individuals

14 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17671643

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Haplotypes of transcription factor 7-like 2 (TCF7L2) gene and its upstream region are associated with type 2 diabetes and age of onset in Mexican Americans

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17671643

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Replication study for the association of TCF7L2 with susceptibility to type 2 diabetes in a Japanese population

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17671643

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1172/JCI33077

1 reference

11 August 2017

1 reference

11 August 2017

1 reference

PMCID

1934573