CYLD negatively regulates transforming growth factor-β-signalling via deubiquitinating Akt (Q35916665)

11 August 2017

CYLD negatively regulates transforming growth factor-β-signalling via deubiquitinating Akt (English)

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11 August 2017

Jae Hyang Lim

1

1 reference

11 August 2017

Hirofumi Jono

2

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11 August 2017

Kensei Komatsu

3

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11 August 2017

Chang-Hoon Woo

4

1 reference

11 August 2017

Jiyun Lee

5

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11 August 2017

Masanori Miyata

6

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11 August 2017

Takashi Matsuno

7

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11 August 2017

Xiangbin Xu

8

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11 August 2017

Yuxian Huang

9

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11 August 2017

Wenhong Zhang

10

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11 August 2017

Soo Hyun Park

11

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11 August 2017

Yu-Il Kim

12

1 reference

11 August 2017

Yoo-Duk Choi

13

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11 August 2017

Huahao Shen

14

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11 August 2017

Kyung-Sun Heo

15

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11 August 2017

Haodong Xu

16

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11 August 2017

Patricia Bourne

17

1 reference

11 August 2017

Tomoaki Koga

18

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11 August 2017

Haidong Xu

19

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11 August 2017

Chen Yan

20

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11 August 2017

Binghe Wang

21

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11 August 2017

Lin-Feng Chen

22

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11 August 2017

Xin-Hua Feng

23

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11 August 2017

Jian-Dong Li

24

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11 August 2017

language of work or name

English

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publication date

10 April 2012

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11 August 2017

Nature Communications

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11 August 2017

3

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11 August 2017

771

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Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

11 August 2017

start time

1 January 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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exact match

https://scigraph.springernature.com/pub.10.1038/ncomms1776

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cites work

PAI-1 in tissue fibrosis

1 reference

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WRAP53 is essential for Cajal body formation and for targeting the survival of motor neuron complex to Cajal bodies

27 July 2018

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Dual function of MyD88 in RAS signaling and inflammation, leading to mouse and human cell transformation

27 July 2018

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Novel role of C terminus of Hsc70-interacting protein (CHIP) ubiquitin ligase on inhibiting cardiac apoptosis and dysfunction via regulating ERK5-mediated degradation of inducible cAMP early repressor.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3337989

Ubiquitin chain cleavage: CYLD at work

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3337989

The E3 ligase TRAF6 regulates Akt ubiquitination and activation

27 July 2018

1 reference

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Truncation of the catalytic domain of the cylindromatosis tumor suppressor impairs lung maturation

27 July 2018

1 reference

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CYLD: a tumor suppressor deubiquitinase regulating NF-kappaB activation and diverse biological processes

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3337989

PI3K/Akt pathway activation attenuates the cytotoxic effect of methyl jasmonate toward sarcoma cells

27 July 2018

1 reference

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The fibrinolytic system and the regulation of lung epithelial cell proteolysis, signaling, and cellular viability

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3337989

Regulation of TGF-beta family signaling by E3 ubiquitin ligases

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3337989

PI3K pathway alterations in cancer: variations on a theme

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3337989

Transgelin is a direct target of TGF-beta/Smad3-dependent epithelial cell migration in lung fibrosis

27 July 2018

1 reference

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Axin and GSK3- control Smad3 protein stability and modulate TGF- signaling

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3337989

Cyld inhibits tumor cell proliferation by blocking Bcl-3-dependent NF-kappaB signaling

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3337989

Regulation of T cell development by the deubiquitinating enzyme CYLD

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3337989

Smad transcription factors

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3337989

The tumor suppressor cylindromatosis (CYLD) acts as a negative regulator for toll-like receptor 2 signaling via negative cross-talk with TRAF6 AND TRAF7.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3337989

Specificity and versatility in tgf-beta signaling through Smads

27 July 2018

1 reference

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BMP-7 opposes TGF-beta1-mediated collagen induction in mouse pulmonary myofibroblasts through Id2.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3337989

CHIP controls the sensitivity of transforming growth factor-beta signaling by modulating the basal level of Smad3 through ubiquitin-mediated degradation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3337989

Smad3 null mice develop airspace enlargement and are resistant to TGF-beta-mediated pulmonary fibrosis

27 July 2018

1 reference

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New insights into TGF-beta-Smad signalling

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3337989

The role of transforming growth factor beta in lung development and disease

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3337989

The tumour suppressor CYLD negatively regulates NF-kappaB signalling by deubiquitination

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3337989

Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-kappaB

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3337989

CYLD is a deubiquitinating enzyme that negatively regulates NF-kappaB activation by TNFR family members

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3337989

Transforming Growth Factor-β-Smad Signaling Pathway Negatively Regulates Nontypeable Haemophilus influenzae-induced MUC5AC Mucin Transcription via Mitogen-activated Protein Kinase (MAPK) Phosphatase-1-dependent Inhibition of p38 MAPK

27 July 2018

1 reference

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Transforming growth factor-beta -Smad signaling pathway cooperates with NF-kappa B to mediate nontypeable Haemophilus influenzae-induced MUC2 mucin transcription

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3337989

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

27 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3337989

Inactivation of glycogen synthase kinase-3 beta by phosphorylation: new kinase connections in insulin and growth-factor signalling

27 July 2018

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Abnormal alveolar epithelial repair associated with failure of resolution in experimental streptococcal pneumonia

27 July 2018

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Concomitant loss of transforming growth factor (TGF)-beta receptor types I and II in TGF-beta-resistant cell mutants implicates both receptor types in signal transduction.

27 July 2018

1 reference

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From lung injury to fibrosis

27 July 2018

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The lysophosphatidic acid receptor LPA1 links pulmonary fibrosis to lung injury by mediating fibroblast recruitment and vascular leak

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3337989

Role of p38 MAP kinase and transforming growth factor-beta signaling in transepithelial migration of invasive bacterial pathogens.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3337989

Inflammation-associated remodelling and fibrosis in the lung - a process and an end point

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3337989

TGF-beta and Smad3 signaling link inflammation to chronic fibrogenesis

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3337989

CHIP mediates degradation of Smad proteins and potentially regulates Smad-induced transcription

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3337989

PAI-1, fibrosis, and the elusive provisional fibrin matrix

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3337989

Bleomycin-induced pulmonary fibrosis in fibrinogen-null mice.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3337989

Interstitial fibrosis and growth factors

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3337989

Cytokines and pulmonary fibrosis

24 September 2018

1 reference

12 December 2020

The transforming growth factor-beta-Smad3/4 signaling pathway acts as a positive regulator for TLR2 induction by bacteria via a dual mechanism involving functional cooperation with NF-kappaB and MAPK phosphatase 1-dependent negative cross-talk with

1 reference

12 December 2020

Tumor suppressor CYLD regulates acute lung injury in lethal Streptococcus pneumoniae infections

1 reference

12 December 2020

3-(Hydroxymethyl)-bearing phosphatidylinositol ether lipid analogues and carbonate surrogates block PI3-K, Akt, and cancer cell growth

1 reference

12 December 2020

Identifiers

DOI

10.1038/NCOMMS1776

1 reference

Dimensions Publication ID

11 August 2017

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0 references

1 reference

11 August 2017

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