TLK1B mediated phosphorylation of Rad9 regulates its nuclear/cytoplasmic localization and cell cycle checkpoint (Q35918497)

11 August 2017

TLK1B mediated phosphorylation of Rad9 regulates its nuclear/cytoplasmic localization and cell cycle checkpoint (English)

1 reference

11 August 2017

Sanket Awate

1

1 reference

11 August 2017

Arrigo De Benedetti

series ordinal

2

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11 August 2017

9 February 2016

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11 August 2017

BMC Molecular Biology

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11 August 2017

17

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11 August 2017

3

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Creative Commons Attribution 4.0 International

11 August 2017

start time

9 February 2016

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April 2022 Public Data File from Crossref

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copyrighted

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describes a project that uses

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4746922/fullTextXML

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cites work

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Distinct roles for DNA-PK, ATM and ATR in RPA phosphorylation and checkpoint activation in response to replication stress

27 July 2018

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Epigenetic regulation of genomic integrity

27 July 2018

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The RAD9-RAD1-HUS1 (9.1.1) complex interacts with WRN and is crucial to regulate its response to replication fork stalling

27 July 2018

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The Werner syndrome protein: linking the replication checkpoint response to genome stability

27 July 2018

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Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications

27 July 2018

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Molecular cooperation between the Werner syndrome protein and replication protein A in relation to replication fork blockage

27 July 2018

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ATR and ATM differently regulate WRN to prevent DSBs at stalled replication forks and promote replication fork recovery

27 July 2018

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Human RPA phosphorylation by ATR stimulates DNA synthesis and prevents ssDNA accumulation during DNA-replication stress

27 July 2018

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Formation of dynamic gamma-H2AX domains along broken DNA strands is distinctly regulated by ATM and MDC1 and dependent upon H2AX densities in chromatin.

27 July 2018

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ATR and Rad17 collaborate in modulating Rad9 localisation at sites of DNA damage.

27 July 2018

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Differential involvement of phosphatidylinositol 3-kinase-related protein kinases in hyperphosphorylation of replication protein A2 in response to replication-mediated DNA double-strand breaks

27 July 2018

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Mammalian Rad9 plays a role in telomere stability, S- and G2-phase-specific cell survival, and homologous recombinational repair

27 July 2018

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The radioresistance kinase TLK1B protects the cells by promoting repair of double strand breaks

27 July 2018

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The C. elegans Tousled-like kinase contributes to chromosome segregation as a substrate and regulator of the Aurora B kinase.

27 July 2018

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Interaction and colocalization of Rad9/Rad1/Hus1 checkpoint complex with replication protein A in human cells

27 July 2018

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Deletion of mouse rad9 causes abnormal cellular responses to DNA damage, genomic instability, and embryonic lethality

27 July 2018

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Dial 9-1-1 for DNA damage: the Rad9-Hus1-Rad1 (9-1-1) clamp complex

27 July 2018

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Disruption of the Rad9/Rad1/Hus1 (9-1-1) complex leads to checkpoint signaling and replication defects

27 July 2018

1 reference

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Translation of the radioresistance kinase TLK1B is induced by gamma-irradiation through activation of mTOR and phosphorylation of 4E-BP1

27 July 2018

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Biochemical characterization of DNA damage checkpoint complexes: clamp loader and clamp complexes with specificity for 5' recessed DNA

27 July 2018

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A dominant negative mutant of TLK1 causes chromosome missegregation and aneuploidy in normal breast epithelial cells

27 July 2018

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Tousled-like kinase functions with the chromatin assembly pathway regulating nuclear divisions

27 July 2018

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A Role for the Phosphorylation of hRad9 in Checkpoint Signaling

27 July 2018

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Phosphorylation of Human Rad9 Is Required for Genotoxin-activated Checkpoint Signaling

27 July 2018

1 reference

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Chk1 regulates the S phase checkpoint by coupling the physiological turnover and ionizing radiation-induced accelerated proteolysis of Cdc25A.

27 July 2018

1 reference

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Human Tousled like kinases are targeted by an ATM- and Chk1-dependent DNA damage checkpoint

27 July 2018

1 reference

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DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

27 July 2018

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The Tousled gene in A. thaliana encodes a protein kinase homolog that is required for leaf and flower development

27 July 2018

1 reference

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Mutator phenotype of Werner syndrome is characterized by extensive deletions

27 July 2018

1 reference

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DNA-PKcs is required to maintain stability of Chk1 and Claspin for optimal replication stress response

27 July 2018

1 reference

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Tousled-like kinase-dependent phosphorylation of Rad9 plays a role in cell cycle progression and G2/M checkpoint exit

24 September 2018

1 reference

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Phenothiazine Inhibitors of TLKs Affect Double-Strand Break Repair and DNA Damage Response Recovery and Potentiate Tumor Killing with Radiomimetic Therapy

24 September 2018

1 reference

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DNA structure-specific priming of ATR activation by DNA-PKcs

24 September 2018

1 reference

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ANTI-SILENCING FUNCTION1 proteins are involved in ultraviolet-induced DNA damage repair and are cell cycle regulated by E2F transcription factors in Arabidopsis

24 September 2018

1 reference

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Contributions of Rad9 to tumorigenesis

24 September 2018

1 reference

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The role of RAD9 in tumorigenesis

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746922

TLK1B promotes repair of DSBs via its interaction with Rad9 and Asf1.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746922

Tousled homolog, TLK1, binds and phosphorylates Rad9; TLK1 acts as a molecular chaperone in DNA repair.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746922

Rad9 has a functional role in human prostate carcinogenesis

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746922

Tousled-like kinase in a microbial eukaryote regulates spindle assembly and S-phase progression by interacting with Aurora kinase and chromatin assembly factors

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746922

The protein kinase TOUSLED is required for maintenance of transcriptional gene silencing in Arabidopsis

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746922

TLK1B promotes repair of UV-damaged DNA through chromatin remodeling by Asf1

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746922

RPA2 is a direct downstream target for ATR to regulate the S-phase checkpoint

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746922

Replication protein A directs loading of the DNA damage checkpoint clamp to 5'-DNA junctions

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746922

Role of mammalian Rad9 in genomic stability and ionizing radiation response.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746922

Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746922

The C. elegans Tousled-like kinase (TLK-1) has an essential role in transcription.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746922

Chk1 and Chk2 kinases in checkpoint control and cancer

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746922

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746922

Ataxia-telangiectasia-mutated (ATM) and NBS1-dependent phosphorylation of Chk1 on Ser-317 in response to ionizing radiation

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746922

Regulation of ATR substrate selection by Rad17-dependent loading of Rad9 complexes onto chromatin

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746922

Cell cycle checkpoint signaling through the ATM and ATR kinases

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746922

Identification of human Asf1 chromatin assembly factors as substrates of Tousled-like kinases

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746922

A translationally regulated Tousled kinase phosphorylates histone H3 and confers radioresistance when overexpressed

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746922

The many substrates and functions of ATM

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746922

The Werner syndrome protein: an update

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746922

Inactivation of mouse Hus1 results in genomic instability and impaired responses to genotoxic stress

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746922

The Werner syndrome protein: an update

24 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1186%2FS12867-016-0056-X

Up-regulation of TLK1B by eIF4E overexpression predicts cancer recurrence in irradiated patients with breast cancer

21 January 2018

1 reference

12 December 2020

Spontaneous and induced chromosomal instability in Werner syndrome

1 reference

12 December 2020

Correlation of TLK1B in elevation and recurrence in doxorubicin-treated breast cancer patients with high eIF4E overexpression

1 reference

12 December 2020

In vitro studies of Werner syndrome cells: aberrant growth and chromosome behavior

1 reference

12 December 2020

10.1186/S12867-016-0056-X

Identifiers

DOI

1 reference

Dimensions Publication ID

11 August 2017

0 references

1 reference

11 August 2017

PubMed publication ID

26860083

1 reference