Ets2 regulates colonic stem cells and sensitivity to tumorigenesis (Q35920677)

11 August 2017

Ets2 regulates colonic stem cells and sensitivity to tumorigenesis (English)

1 reference

11 August 2017

Jorge Múnera

1

1 reference

11 August 2017

Grace Ceceña

2

1 reference

11 August 2017

Paul Jedlicka

3

1 reference

11 August 2017

Miriam Wankell

4

1 reference

11 August 2017

Robert G Oshima

5

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11 August 2017

1 March 2011

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11 August 2017

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11 August 2017

29

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11 August 2017

3

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11 August 2017

430-439

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Intestinal crypt homeostasis results from neutral competition between symmetrically dividing Lgr5 stem cells

11 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339631

Tumour angiogenesis is reduced in the Tc1 mouse model of Down's syndrome

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339631

Matrix metalloproteinase-9 functions as a tumor suppressor in colitis-associated cancer

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339631

Pten in stromal fibroblasts suppresses mammary epithelial tumours

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339631

The ets-domain transcription factor Spdef promotes maturation of goblet and paneth cells in the intestinal epithelium

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339631

Transcription factor achaete scute-like 2 controls intestinal stem cell fate

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339631

The adaptor protein of the anaphase promoting complex Cdh1 is essential in maintaining replicative lifespan and in learning and memory

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339631

Crypt stem cells as the cells-of-origin of intestinal cancer

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339631

Putative direct and indirect Wnt targets identified through consistent gene expression changes in APC-mutant intestinal adenomas from humans and mice

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339631

Ets2 is required for trophoblast stem cell self-renewal

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339631

An inducible mouse model of colon carcinogenesis for the analysis of sporadic and inflammation-driven tumor progression

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339631

Matrix metalloproteinase-9 regulates MUC-2 expression through its effect on goblet cell differentiation

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339631

The Intestinal Wnt/TCF Signature.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339631

PTEN-deficient intestinal stem cells initiate intestinal polyposis

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339631

Rapid loss of intestinal crypts upon conditional deletion of the Wnt/Tcf-4 target gene c-Myc

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339631

Epimorphin(-/-) mice have increased intestinal growth, decreased susceptibility to dextran sodium sulfate colitis, and impaired spermatogenesis

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339631

Mitochondrial DNA mutations are established in human colonic stem cells, and mutated clones expand by crypt fission.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339631

IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339631

Ets2-dependent stromal regulation of mouse mammary tumors

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339631

The Cdx2 homeobox gene has a tumour suppressor function in the distal colon in addition to a homeotic role during gut development.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339631

The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339631

Opposing effects of Ets and Id proteins on p16INK4a expression during cellular senescence

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339631

Generalized lacZ expression with the ROSA26 Cre reporter strain

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339631

APC in the regulation of intestinal crypt fission

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339631

Defective trophoblast function in mice with a targeted mutation of Ets2.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339631

Clonality and life cycles of intestinal crypts explained by a state dependent stochastic model of epithelial stem cell organization

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339631

Promotion of colorectal neoplasia in experimental murine ulcerative colitis

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339631

The ETS domain protein pointed-P2 is a target of MAP kinase in the sevenless signal transduction pathway

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339631

Crypt fission in the small intestine and colon. A mechanism for the emergence of G6PD locus-mutated crypts after treatment with mutagens

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339631

Ets2-dependent microenvironmental support of mouse mammary tumors

11 July 2018

1 reference

Cis elements of the villin gene control expression in restricted domains of the vertical (crypt) and horizontal (duodenum, cecum) axes of the intestine.

21 January 2018

1 reference

Z/AP, a double reporter for cre-mediated recombination.

21 January 2018

1 reference

Transforming growth factor beta receptor type II inactivation promotes the establishment and progression of colon cancer

21 January 2018

1 reference

LGR5 deficiency deregulates Wnt signaling and leads to precocious Paneth cell differentiation in the fetal intestine

21 January 2018

1 reference

c-myb Heterozygous mice are hypersensitive to 5-fluorouracil and ionizing radiation

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339631

A single targeted Ets2 allele restricts development of mammary tumors in transgenic mice.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339631

Trisomy represses Apc Min -mediated tumours in mouse models of Down’s syndrome

24 September 2018

1 reference

Derivation of mouse intestinal crypts from single progenitor cells

21 January 2018

1 reference

Whole population cell kinetics and postnatal development of the mouse intestinal epithelium

21 January 2018

1 reference

12 December 2020

Development of the pattern of cell renewal in the crypt-villus unit of chimaeric mouse small intestine

1 reference

12 December 2020

Morphological changes and cellular proliferation in mouse colon during fetal and postnatal development

1 reference

12 December 2020

Conserved mechanisms of Ras regulation of evolutionary related transcription factors, Ets1 and Pointed P2

1 reference

12 December 2020

Colonic hamartoma development by anomalous duplication in Cdx2 knockout mice

1 reference

12 December 2020

Identifiers

DOI

10.1002/STEM.599

1 reference

11 August 2017

1 reference

11 August 2017

PubMed publication ID

21425406

1 reference