Peroxisome proliferator-activated receptors: mediators of phthalate ester-induced effects in the male reproductive tract? (Q35924008)

11 August 2017

1 reference

title

Peroxisome proliferator-activated receptors: mediators of phthalate ester-induced effects in the male reproductive tract? (English)

1 reference

11 August 2017

J Christopher Corton

1

1 reference

PubMed ID

15496498

11 August 2017

Paula J Lapinskas

series ordinal

2

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11 August 2017

20 October 2004

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11 August 2017

Toxicological Sciences

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11 August 2017

83

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11 August 2017

1

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11 August 2017

4-17

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Modulation of rat Leydig cell steroidogenic function by di(2-ethylhexyl)phthalate

11 August 2017

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

Phthalate-induced Leydig cell hyperplasia is associated with multiple endocrine disturbances

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

Hepatic expression of acute-phase protein genes during carcinogenesis induced by peroxisome proliferators

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

Male reproductive tract lesions at 6, 12, and 18 months of age following in utero exposure to di(n-butyl) phthalate

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

Quantitative Changes in Gene Expression in Fetal Rat Testes following Exposure to Di(n-butyl) Phthalate

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

PPAR gamma is required for placental, cardiac, and adipose tissue development

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

Increase in testicular cancer incidence in six European countries: a birth cohort phenomenon

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

Comparison of the effects of Wyeth-14,643 in Crl:CD BR and Fisher-344 rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

Mechanisms of extrahepatic tumor induction by peroxisome proliferators in male CD rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

Activation of mouse and human peroxisome proliferator-activated receptors (PPARs) by phthalate monoesters

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

Induction of Leydig cell adenomas by ammonium perfluorooctanoate: a possible endocrine-related mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

Central role of peroxisome proliferator-activated receptors in the actions of peroxisome proliferators

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

Testicular toxicity and reduced sertoli cell numbers in neonatal rats by di(2-ethylhexyl) phthalate and the recovery of fertility as adults

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

Molecular cloning, expression and characterization of human peroxisome proliferator activated receptors gamma 1 and gamma 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

Effects on development of the reproductive system in male offspring of rats given butyl benzyl phthalate during late pregnancy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

PPARalpha activators down-regulate CYP2C7, a retinoic acid and testosterone hydroxylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

Regulation of phase I and phase II steroid metabolism enzymes by PPAR alpha activators

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

Human 'testicular dysgenesis syndrome': a possible model using in-utero exposure of the rat to dibutyl phthalate

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

Studies on the testicular effects and zinc excretion produced by various isomers of monobutyl-o-phthalate in the rat

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

Effects of phthalate esters on the developing reproductive tract of male rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

Overexpression of SR-BI by adenoviral vector reverses the fibrateinduced hypercholesterolemia of apolipoprotein E-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

Testicular effects of phthalate esters

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

Death receptor response in rodent testis after mono-(2-ethylhexyl) phthalate exposure

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

Species differences in the testicular toxicity of phthalate esters

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

Administration of potentially antiandrogenic pesticides (procymidone, linuron, iprodione, chlozolinate, p,p'-DDE, and ketoconazole) and toxic substances (dibutyl- and diethylhexyl phthalate, PCB 169, and ethane dimethane sulphonate) during sexual di

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

Perinatal exposure to the phthalates DEHP, BBP, and DINP, but not DEP, DMP, or DOTP, alters sexual differentiation of the male rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

Aspects of the testicular toxicity of phthalate esters

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

Dehydroepiandrosterone affects the expression of multiple genes in rat liver including 11 beta-hydroxysteroid dehydrogenase type 1: a cDNA array analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

Expression of peroxisome proliferator-activated receptors in human testicular cancer and growth inhibition by its agonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

Inhibition of FSH-stimulated cAMP accumulation by mono(2-ethylhexyl) phthalate in primary rat Sertoli cell cultures.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

Phthalate ester effects on rat Sertoli cell function in vitro: effects of phthalate side chain and age of animal

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

Effects of dibutyl phthalate in male rabbits following in utero, adolescent, or postpubertal exposure

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

Activation of PPARalpha and PPARgamma by environmental phthalate monoesters

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

Co-localized expression of FasL, Fas, Caspase-3 and apoptotic DNA fragmentation in mouse testis after oral exposure to di(2-ethylhexyl)phthalate

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

The biological effect of phthalate esters on transabdominal migration of the testis in fetal rats in comparison with the antiandrogen flutamide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

Role of oxidative stress in germ cell apoptosis induced by di(2-ethylhexyl)phthalate

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

Short period exposure to di-(2-ethylhexyl) phthalate regulates testosterone metabolism in testis of prepubertal rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

PPARalpha agonist-induced rodent tumors: modes of action and human relevance

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

Studies on the effects of orally administered Di-(2-ethylhexyl) phthalate in the ferret

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

Teratogenic phthalate esters and metabolites activate the nuclear receptors PPARs and induce differentiation of F9 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

Targeted disruption of the alpha isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

Dose-dependent alterations in gene expression and testosterone synthesis in the fetal testes of male rats exposed to di (n-butyl) phthalate

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

Peroxisome proliferator-activated receptors: a nuclear receptor signaling pathway in lipid physiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

Effects of mono-(2-ethylhexyl) phthalate on fetal and neonatal rat testis organ cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

Effects of relatively low levels of mono-(2-ethylhexyl) phthalate on cocultured Sertoli cells and gonocytes from neonatal rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

The direct effect of hepatic peroxisome proliferators on rat Leydig cell function in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

Effect of mono-(2-ethylhexyl)phthalate on follicle-stimulating hormone responsiveness of cultured rat Sertoli cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

Biochemical mechanisms of induction of hepatic peroxisome proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

Mono-(2-ethylhexyl) phthalate suppresses aromatase transcript levels and estradiol production in cultured rat granulosa cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

Dual activation of PPARα and PPARγ by mono-(2-ethylhexyl) phthalate in rat ovarian granulosa cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

Interactions of fluorochemicals with rat liver fatty acid-binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

Hepatic scavenger receptor class B, type I is stimulated by peroxisome proliferator-activated receptor gamma and hepatocyte nuclear factor 4alpha.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

trans-Activation of PPARalpha and PPARgamma by structurally diverse environmental chemicals

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

Fibrates down-regulate hepatic scavenger receptor class B type I protein expression in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

Definition of the molecular and cellular mechanisms underlying the tissue-selective agonist/antagonist activities of selective estrogen receptor modulators

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

The oestrogenic potential of the phthalate esters

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

Abnormalities of sexual development in male rats with in utero and lactational exposure to the antiandrogenic plasticizer Di(2-ethylhexyl) phthalate

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

Combined treatment with specific ligands for PPARgamma:RXR nuclear receptor system markedly inhibits the expression of cytochrome P450arom in human granulosa cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

Disruption of androgen-regulated male reproductive development by di(n-butyl) phthalate during late gestation in rats is different from flutamide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

Fetal testosterone insufficiency and abnormal proliferation of Leydig cells and gonocytes in rats exposed to di(n-butyl) phthalate

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

Effect of butyl benzyl phthalate in Sprague-Dawley rats after gavage administration: a two-generation reproductive study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

Development of a scintillation proximity assay for peroxisome proliferator-activated receptor gamma ligand binding domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

Effects of dibutyl phthalate as an environmental endocrine disruptor on gonadal sex differentiation of genetic males of the frog Rana rugosa

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

The plasticizer diethylhexyl phthalate induces malformations by decreasing fetal testosterone synthesis during sexual differentiation in the male rat

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

Regulation of the Seminiferous Epithelium*

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

Growth, adipose, brain, and skin alterations resulting from targeted disruption of the mouse peroxisome proliferator-activated receptor beta(delta)

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

Developmental toxicity of butyl benzyl phthalate in the rat using a multiple dose study design.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

Defining the cellular and molecular mechanisms of toxicant action in the testis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

Effects of clofibric acid on mRNA expression profiles in primary cultures of rat, mouse and human hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

Regulation of CYP2C11 by dehydroepiandrosterone and peroxisome proliferators: identification of the negative regulatory region of the gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

Comparison of oxidative stress and changes of xenobiotic metabolizing enzymes induced by phthalates in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

Hormones and testis development and the possible adverse effects of environmental chemicals

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

Dose-dependent effect of phthalate ester on testicular descent in pre-and post natal rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

Altered gene profiles in fetal rat testes after in utero exposure to di(n-butyl) phthalate

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

Testicular dysgenesis syndrome: an increasingly common developmental disorder with environmental aspects

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

The effects of mono-2-ethylhexyl phathalate, adriamycin and N-ethyl-N-nitrosourea on stage-specific apoptosis and DNA synthesis in the mouse spermatogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

Di(n-Butyl) Phthalate Impairs Cholesterol Transport and Steroidogenesis in the Fetal Rat Testis through a Rapid and Reversible Mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

Fenofibrate, a ligand for PPARalpha, inhibits aromatase cytochrome P450 expression in the ovary of mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

Male reproductive health and environmental xenoestrogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

Reproductive toxicity evaluation of dietary butyl benzyl phthalate (BBP) in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

SF-1 a key player in the development and differentiation of steroidogenic tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

Role of the peroxisome proliferator-activated receptor alpha in responses to diisononyl phthalate

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

Phthalate ester-induced gubernacular lesions are associated with reduced insl3 gene expression in the fetal rat testis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

Reproductive toxicity of di-n-butylphthalate in a continuous breeding protocol in Sprague-Dawley rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

Gene expression changes induced in mouse liver by di(2-ethylhexyl) phthalate

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

Rat PPAR delta contains a CGG triplet repeat and is prominently expressed in the thalamic nuclei

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

Molecular recognition of fatty acids by peroxisome proliferator-activated receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

PPARalpha-dependent induction of liver microsomal esterification of estradiol and testosterone by a prototypical peroxisome proliferator

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI011

21 January 2018

Identifiers

DOI

10.1093/TOXSCI/KFI011

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/mp4qvq66cfhafech5mpcnemlcu

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30 July 2022

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Fatcat ID

release_mp4qvq66cfhafech5mpcnemlcu

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/mp4qvq66cfhafech5mpcnemlcu

mapped directly with Wikidata item

30 July 2022

based on heuristic

1 reference

https://api.fatcat.wiki/v0/release/mp4qvq66cfhafech5mpcnemlcu