Development of gene-specific double-stranded RNA drugs (Q35932393)

11 August 2017

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title

Development of gene-specific double-stranded RNA drugs (English)

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11 August 2017

1

Sailen Barik

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PubMed ID

15513304

11 August 2017

language of work or name

English

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publication date

1 January 2004

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11 August 2017

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11 August 2017

36

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11 August 2017

7

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11 August 2017

540-551

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11 August 2017

In search of antisense

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018817

RNAi: an ever-growing puzzle

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018817

RNA interference in functional genomics and medicine

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018817

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018817

Evidence that siRNAs function as guides, not primers, in the Drosophila and human RNAi pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018817

RNAi in human cells: basic structural and functional features of small interfering RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018817

Asymmetry in the assembly of the RNAi enzyme complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018817

Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018817

A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018817

Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018817

MicroRNAs: genomics, biogenesis, mechanism, and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018817

The nuclear RNase III Drosha initiates microRNA processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018817

21 January 2018

Viruses and interferons

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018817

Phenotypic silencing of cytoplasmic genes using sequence-specific double-stranded short interfering RNA and its application in the reverse genetics of wild type negative-strand RNA viruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018817

Interferon induction by siRNAs and ssRNAs synthesized by phage polymerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018817

Short interfering RNA-directed inhibition of hepatitis B virus replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018817

Inhibition of hepatitis B virus in mice by RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018817

Inhibition of hepatitis B virus expression and replication by RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018817

Selective inhibition of hepatitis B virus replication by RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018817

Inhibition of gammaherpesvirus replication by RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018817

Selective silencing of viral gene expression in HPV-positive human cervical carcinoma cells treated with siRNA, a primer of RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018817

Potent and specific inhibition of human immunodeficiency virus type 1 replication by RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018817

RNA interference directed against viral and cellular targets inhibits human immunodeficiency Virus Type 1 replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018817

Inhibition of human immunodeficiency virus type 1 replication in primary macrophages by using Tat- or CCR5-specific small interfering RNAs expressed from a lentivirus vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018817

Prevention of HIV-1 infection in human peripheral blood mononuclear cells by specific RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018817

Inhibiting HIV-1 infection in human T cells by lentiviral-mediated delivery of small interfering RNA against CCR5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018817

Potent suppression of HIV type 1 infection by a short hairpin anti-CXCR4 siRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018817

RNA silencing of dengue virus type 2 replication in transformed C6/36 mosquito cells transcribing an inverted-repeat RNA derived from the virus genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018817

Inhibition of viral gene expression and replication in mosquito cells by dsRNA-triggered RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018817

Interference of hepatitis C virus RNA replication by short interfering RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018817

Small Interfering RNA-Mediated Inhibition of Hepatitis C Virus Replication in the Human Hepatoma Cell Line Huh-7

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018817

Inhibition of intracellular hepatitis C virus replication by synthetic and vector-derived small interfering RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018817

Inhibition of hepatitis C virus protein expression by RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018817

Susceptibility of human hepatitis delta virus RNAs to small interfering RNA action

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018817

RNA interference of influenza virus production by directly targeting mRNA for degradation and indirectly inhibiting all viral RNA transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018817

Inhibition of influenza virus production in virus-infected mice by RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018817

Protection against lethal influenza virus challenge by RNA interference in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018817

Rotavirus gene silencing by small interfering RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018817

Profilin is required for viral morphogenesis, syncytium formation, and cell-specific stress fiber induction by respiratory syncytial virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018817

Control of nonsegmented negative-strand RNA virus replication by siRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018817

New drugs and treatment for respiratory syncytial virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018817

Current treatment strategies for chronic hepatitis B and C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018817

RNA interference in human cells is restricted to the cytoplasm

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018817

SiRNA based strategies for inhibition of apoptotic pathways in vivo--analytical and therapeutic implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018817

Caspase 8 small interfering RNA prevents acute liver failure in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018817

RNA interference (RNAi) inhibits growth of Plasmodium falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018817

Double-stranded RNA-mediated gene silencing of cysteine proteases (falcipain-1 and -2) of Plasmodium falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018817

RNA interference: advances and questions

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018817

The cAMP-specific phosphodiesterase TbPDE2C is an essential enzyme in bloodstream form Trypanosoma brucei

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018817

Using RNA interference to manipulate endogenous gene expression in Schistosoma mansoni sporocysts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018817

Improvements in transfection efficiency and tests of RNA interference (RNAi) approaches in the protozoan parasite Leishmania

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018817

Tests of cytoplasmic RNA interference (RNAi) and construction of a tetracycline-inducible T7 promoter system in Trypanosoma cruzi.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018817

Comparison of antisense oligonucleotides and siRNAs in cell culture and in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018817

Vascular endothelial growth factor gene regulation and action in diabetic retinopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018817

Killing cancer by targeting genes that cancer cells have lost: allele-specific inhibition, a novel approach to the treatment of genetic disorders.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018817

Allele-specific silencing of dominant disease genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018817

Synthetic small inhibiting RNAs: efficient tools to inactivate oncogenic mutations and restore p53 pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018817

Design and evaluation of chemically synthesized siRNA targeting the NPM-ALK fusion site in anaplastic large cell lymphoma (ALCL).

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018817

Inducible shRNA expression for application in a prostate cancer mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018817

Adenoviral vectors expressing siRNAs for discovery and validation of gene function

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018817

Conditional suppression of cellular genes: lentivirus vector-mediated drug-inducible RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018817

Gene therapy: trials and tribulations

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018817

Tolerance for mutations and chemical modifications in a siRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018817

Effects on RNA interference in gene expression (RNAi) in cultured mammalian cells of mismatches and the introduction of chemical modifications at the 3'-ends of siRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018817

Approaches for the sequence-specific knockdown of mRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018817

Human immunodeficiency virus type 1 escapes from RNA interference-mediated inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018817

Rational siRNA design for RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018817

Expression profiling reveals off-target gene regulation by RNAi

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018817

Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents. A comparative analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018817

Unlocking the money-making potential of RNAi.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410018817

10.1080/07853890410018817

21 January 2018

Identifiers

DOI

1 reference

11 August 2017

1 reference

PubMed ID

15513304