Antitumour effects of antiretroviral therapy (Q35934144)

11 August 2017

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title

Antitumour effects of antiretroviral therapy (English)

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11 August 2017

main subject

anti-retroviral agent

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Cecilia Sgadari

2

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Paolo Monini

object named as

Paolo Monini

1

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Barbara Ensoli

object named as

Barbara Ensoli

5

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author name string

Elena Toschi

3

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11 August 2017

Giovanni Barillari

4

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11 August 2017

language of work or name

English

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publication date

1 November 2004

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11 August 2017

published in

Nature Reviews Cancer

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11 August 2017

volume

4

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11 August 2017

issue

11

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11 August 2017

page(s)

861-875

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Trends in the incidence of outcomes defining acquired immunodeficiency syndrome (AIDS) in the Multicenter AIDS Cohort Study: 1985-1991.

11 August 2017

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Early regression of cervical lesions in HIV-seropositive women receiving highly active antiretroviral therapy

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Antiretroviral treatment regimens and immune parameters in the prevention of systemic AIDS-related non-Hodgkin's lymphoma

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Non-Hodgkin lymphoma in HIV-infected patients in the era of highly active antiretroviral therapy

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An inhibitor of HIV-1 protease modulates proteasome activity, antigen presentation, and T cell responses

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HIV protease inhibitors are potent anti-angiogenic molecules and promote regression of Kaposi sarcoma

21 January 2018

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Reactivation and role of HHV-8 in Kaposi's sarcoma initiation

21 January 2018

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21 January 2018

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Seroconversion to antibodies against Kaposi's sarcoma-associated herpesvirus-related latent nuclear antigens before the development of Kaposi's sarcoma

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Elevated virus loads of Kaposi's sarcoma-associated human herpesvirus 8 predict Kaposi's sarcoma disease progression, but elevated levels of human immunodeficiency virus type 1 do not.

21 January 2018

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Detection of Kaposi sarcoma associated herpesvirus in peripheral blood of HIV-infected individuals and progression to Kaposi's sarcoma

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Epstein-Barr virus-specific cytotoxic T cell responses in HIV-1 infection: different kinetics in patients progressing to opportunistic infection or non-Hodgkin's lymphoma

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Parameters affecting the development of non-Hodgkin's lymphoma in patients with severe human immunodeficiency virus infection receiving antiretroviral therapy

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Subpopulations of long-lived and short-lived T cells in advanced HIV-1 infection

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Identification of dynamically distinct subpopulations of T lymphocytes that are differentially affected by HIV

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In vivo dynamics of T cell activation, proliferation, and death in HIV-1 infection: why are CD4+ but not CD8+ T cells depleted?

21 January 2018

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Cytokines from activated T cells induce normal endothelial cells to acquire the phenotypic and functional features of AIDS-Kaposi's sarcoma spindle cells.

21 January 2018

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Synergy between basic fibroblast growth factor and HIV-1 Tat protein in induction of Kaposi's sarcoma

21 January 2018

1 reference

HIV-1 Tat protein exits from cells via a leaderless secretory pathway and binds to extracellular matrix-associated heparan sulfate proteoglycans through its basic region

21 January 2018

1 reference

Tat protein of HIV-1 stimulates growth of cells derived from Kaposi's sarcoma lesions of AIDS patients

21 January 2018

1 reference

Activation of matrix-metalloproteinase-2 and membrane-type-1-matrix-metalloproteinase in endothelial cells and induction of vascular permeability in vivo by human immunodeficiency virus-1 Tat protein and basic fibroblast growth factor

21 January 2018

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Expansion of cytotoxic CD8+ CD28- T cells in healthy ageing people, including centenarians.

21 January 2018

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A whole blood method for measurement of intracellular TNF-alpha, IFN-gamma and IL-2 expression in stimulated CD3+ lymphocytes: differences between young and elderly subjects

21 January 2018

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Marked increase with age of type 1 cytokines within memory and effector/cytotoxic CD8+ T cells in humans: a contribution to understand the relationship between inflammation and immunosenescence.

21 January 2018

1 reference

Immune activation in africa is environmentally-driven and is associated with upregulation of CCR5. Italian-Ugandan AIDS Project.

21 January 2018

1 reference

Endemic African Kaposi's sarcoma is not associated with immunodeficiency

21 January 2018

1 reference

Outcome of kidney transplant recipients with previous human herpesvirus-8 infection

21 January 2018

1 reference

Clinical features and contribution of virological findings to the management of Kaposi sarcoma in organ-allograft recipients.

21 January 2018

1 reference

Multiple monoclonal B cell expansions and c-myc oncogene rearrangements in acquired immune deficiency syndrome-related lymphoproliferative disorders. Implications for lymphomagenesis

21 January 2018

1 reference

Emerging pathways in the development of AIDS-related lymphomas

21 January 2018

1 reference

HIV-1 antigen-specific and -nonspecific B cell responses are sensitive to combination antiretroviral therapy

21 January 2018

1 reference

Kinetics of CD4+ T cell repopulation of lymphoid tissues after treatment of HIV-1 infection

21 January 2018

1 reference

Increased turnover of T lymphocytes in HIV-1 infection and its reduction by antiretroviral therapy

21 January 2018

1 reference

T-cell repopulation and thymic volume in HIV-1-infected adult patients after highly active antiretroviral therapy

21 January 2018

1 reference

Biphasic kinetics of peripheral blood T cells after triple combination therapy in HIV-1 infection: a composite of redistribution and proliferation.

21 January 2018

1 reference

Improved survival in HIV-related Hodgkin's lymphoma since the introduction of highly active antiretroviral therapy

21 January 2018

1 reference

Better response to chemotherapy and prolonged survival in AIDS-related lymphomas responding to highly active antiretroviral therapy

21 January 2018

1 reference

Highly active anti-retroviral therapy (HAART) prolongs time to treatment failure in Kaposi's sarcoma

21 January 2018

1 reference

Response to highly active antiretroviral therapy strongly predicts outcome in patients with AIDS-related lymphoma

21 January 2018

1 reference

Effect of highly active antiretroviral therapy on survival in patients with AIDS-associated pulmonary Kaposi's sarcoma treated with chemotherapy

21 January 2018

1 reference

Highly active antiretroviral therapy and cervical squamous intraepithelial lesions in human immunodeficiency virus-positive women

21 January 2018

1 reference

Effect of highly active antiretroviral therapy on survival among HIV-infected men with Kaposi sarcoma or non-Hodgkin lymphoma

21 January 2018

1 reference

Identification of Kaposi's sarcoma-associated herpesvirus (KSHV)-specific cytotoxic T-lymphocyte epitopes and evaluation of reconstitution of KSHV-specific responses in human immunodeficiency virus type 1-Infected patients receiving highly active an

21 January 2018

1 reference

Reduced incidence of Kaposi's sarcoma and of systemic non-hodgkin's lymphoma in HIV-infected individuals treated with highly active antiretroviral therapy.

21 January 2018

1 reference

Highly active antiretroviral therapy enhances regression of cervical intraepithelial neoplasia in HIV-seropositive women

21 January 2018

1 reference

Analysis and Significance of Anti-Latent Membrane Protein-1 Antibodies in the Sera of Patients with EBV-Associated Diseases

21 January 2018

1 reference

Ex vivo analysis of T-cell responses to Epstein-Barr virus-encoded oncogene latent membrane protein 1 reveals highly conserved epitope sequences in virus isolates from diverse geographic regions.

21 January 2018

1 reference

Long-term remission of an AIDS-related primary effusion lymphoma with antiviral therapy

21 January 2018

1 reference

Effect of excisional therapy and highly active antiretroviral therapy on cervical intraepithelial neoplasia in women infected with human immunodeficiency virus

21 January 2018

1 reference

Improved outcome of cervical neoplasia in HIV-infected women in the era of highly active antiretroviral therapy

21 January 2018

1 reference

Regression and clonally distinct recurrence of human immunodeficiency virus related Burkitt-like lymphoma during antiretroviral therapy

21 January 2018

1 reference

Antiretroviral therapy with protease inhibitors in human immunodeficiency virus type 1- and human herpesvirus 8-coinfected patients

21 January 2018

1 reference

Patterns of lymphotropic herpesvirus viraemia in HIV-infected patients with Kaposi's sarcoma treated with highly active antiretroviral therapy and liposomal daunorubicin.

21 January 2018

1 reference

Short- and long-term effects of highly active antiretroviral therapy on Kaposi sarcoma-associated herpesvirus immune responses and viraemia

21 January 2018

1 reference

The efficacy of ritonavir in the prevention of AIDS-related Kaposi's sarcoma

21 January 2018

1 reference

Prospective study of the effects of antiretroviral therapy on Kaposi sarcoma--associated herpesvirus infection in patients with and without Kaposi sarcoma

21 January 2018

1 reference

Is switching protease inhibitor-based effective antiretroviral therapy safe in patients with AIDS-associated Kaposi's sarcoma?

21 January 2018

1 reference

Antitumorigenic effects of HIV protease inhibitor ritonavir: inhibition of Kaposi sarcoma

21 January 2018

1 reference

AIDS-Kaposi's sarcoma-derived cells express cytokines with autocrine and paracrine growth effects.

21 January 2018

1 reference

Block of AIDS-Kaposi's sarcoma (KS) cell growth, angiogenesis, and lesion formation in nude mice by antisense oligonucleotide targeting basic fibroblast growth factor. A novel strategy for the therapy of KS.

21 January 2018

1 reference

Putting tumours in context

21 January 2018

1 reference

The HIV protease inhibitor Indinavir inhibits cell-cycle progression in vitro in lymphocytes of HIV-infected and uninfected individuals

21 January 2018

1 reference

Differential effects of HIV-1 protease inhibitors on dendritic cell immunophenotype and function

21 January 2018

1 reference

Effects of retroviral protease inhibitors on proteasome function and processing of HIV-derived MHC class I-restricted cytotoxic T lymphocyte epitopes.

21 January 2018

1 reference

HIV protease inhibitor ritonavir induces cytotoxicity of human endothelial cells

21 January 2018

1 reference

How an inhibitor of the HIV-I protease modulates proteasome activity

21 January 2018

1 reference

Protection against experimental autoimmune encephalomyelitis by a proteasome modulator

21 January 2018

1 reference

The human 26S proteasome is a target of antiretroviral agents.

21 January 2018

1 reference

Not just research tools--proteasome inhibitors offer therapeutic promise

21 January 2018

1 reference

Clinical update: proteasome inhibitors in solid tumors

21 January 2018

1 reference

The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa B

21 January 2018

1 reference

Enhancement of radiosensitivity by proteasome inhibition: implications for a role of NF-kappaB.

21 January 2018

1 reference

Proteasome inhibitors as new anticancer drugs

21 January 2018

1 reference

Gamma-interferon and expression of MHC genes regulate peptide hydrolysis by proteasomes

21 January 2018

1 reference

HIV protease inhibitors protect apolipoprotein B from degradation by the proteasome: a potential mechanism for protease inhibitor-induced hyperlipidemia

21 January 2018

1 reference

Role of Rac1 and oxygen radicals in collagenase-1 expression induced by cell shape change

21 January 2018

1 reference

Sequential cleavage by metallopeptidases and proteasomes is involved in processing HIV-1 ENV epitope for endogenous MHC class I antigen presentation

21 January 2018

1 reference

Degradation of interleukin 1beta by matrix metalloproteinases.

21 January 2018

1 reference

Inflammation dampened by gelatinase A cleavage of monocyte chemoattractant protein-3

21 January 2018

1 reference

Immune-mediated eradication of tumors through the blockade of transforming growth factor-beta signaling in T cells

21 January 2018

1 reference

Mutation of the matrix metalloproteinase 2 gene (MMP2) causes a multicentric osteolysis and arthritis syndrome

21 January 2018

1 reference

Accelerated bone mineral loss in HIV-infected patients receiving potent antiretroviral therapy

21 January 2018

1 reference

Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer

21 January 2018

1 reference

21 January 2018

Inflammation and cancer

1 reference

21 January 2018

1 reference

Chemotherapy for human immunodeficiency virus-associated non-Hodgkin's lymphoma in combination with highly active antiretroviral therapy

21 January 2018

1 reference

Paclitaxel in the treatment of human immunodeficiency virus 1-associated Kaposi's sarcoma--drug-drug interactions with protease inhibitors and a nonnucleoside reverse transcriptase inhibitor: a case report study

21 January 2018

1 reference

Concomitant cyclophosphamide, doxorubicin, vincristine, and prednisone chemotherapy plus highly active antiretroviral therapy in patients with human immunodeficiency virus-related, non-Hodgkin lymphoma

21 January 2018

1 reference

Stanford V regimen and concomitant HAART in 59 patients with Hodgkin disease and HIV infection.

21 January 2018

1 reference

Ex vivo and in vitro effect of human immunodeficiency virus protease inhibitors on neutrophil apoptosis

21 January 2018

1 reference

Recovery of hematopoietic activity in bone marrow from human immunodeficiency virus type 1-infected patients during highly active antiretroviral therapy.

21 January 2018

1 reference

The protease inhibitor ritonavir inhibits the functional activity of the multidrug resistance related-protein 1 (MRP-1).

21 January 2018

1 reference

Involvement of proteasomes in migration and matrix metalloproteinase-9 production of oral squamous cell carcinoma

21 January 2018

1 reference

Down-regulation of Flt-1 gene expression by the proteasome inhibitor MG262.

21 January 2018

1 reference

The V3 domain of the HIV-1 gp120 envelope glycoprotein is critical for chemokine-mediated blockade of infection

21 January 2018

1 reference

Evidence for increased T cell turnover and decreased thymic output in HIV infection

21 January 2018

1 reference

Cancer incidence in New York State acquired immunodeficiency syndrome patients

21 January 2018

1 reference

Multicenter study of human immunodeficiency virus-related germ cell tumors

21 January 2018

1 reference

Incidence of non-AIDS-defining cancers before and during the highly active antiretroviral therapy era in a cohort of human immunodeficiency virus-infected patients

21 January 2018

1 reference

Outcome of patients with HIV-related germ cell tumours: a case-control study.

21 January 2018

1 reference

Use of HIV protease inhibitors to block Kaposi's sarcoma and tumour growth

21 January 2018

1 reference

Antiapoptotic mechanism of HIV protease inhibitors: preventing mitochondrial transmembrane potential loss

21 January 2018

1 reference

Highly active antiretroviral therapy inhibits cytokine production in HIV-uninfected subjects

21 January 2018

1 reference

Virologic and Immunologic Parameters that Predict Clinical Response of AIDS-Associated Kaposi's Sarcoma to Highly Active Antiretroviral Therapy

21 January 2018

1 reference

Long-term effect of highly active antiretroviral therapy on cervical lesions in HIV-positive women

21 January 2018

1 reference

Immunological activation markers in the serum of African and European HIV-seropositive and seronegative individuals

21 January 2018

1 reference

Changes in thymic function with age and during the treatment of HIV infection

21 January 2018

1 reference

Processing of tumour necrosis factor-α precursor by metalloproteinases

21 January 2018

1 reference

The in Vivo Effects of Combination Antiretroviral Drug Therapy on Peripheral Blood CD34+ Cell Colony-Forming Units from HIV Type 1-Infected Patients

21 January 2018

1 reference

Positive effects of combined antiretroviral therapy on CD4+ T cell homeostasis and function in advanced HIV disease

21 January 2018

1 reference

Epidermodysplasia verruciformis in a patient with HIV infection: no response to highly active antiretroviral therapy

31 March 2020

1 reference

Immune deficiency and risk for malignancy among persons with AIDS

31 March 2020

1 reference

AIDS-associated non-Hodgkin lymphoma

31 March 2020

1 reference

CD4+ T-cell depletion in HIV infection: Are we closer to understanding the cause?

31 March 2020

1 reference

The role of immunosuppression and immune-activation in classic Kaposi's sarcoma.

31 March 2020

1 reference

Clinical features and course of Kaposi's sarcoma in kidney transplant patients: report of 13 cases

31 March 2020

1 reference

Increased cell division but not thymic dysfunction rapidly affects the T-cell receptor excision circle content of the naive T cell population in HIV-1 infection

31 March 2020

1 reference

Clinical and biological impact of antiretroviral therapy with protease inhibitors on HIV-related Kaposi's sarcoma

31 March 2020

1 reference

31 March 2020

1 reference

Decreasing rates of Kaposi's sarcoma and non-Hodgkin's lymphoma in the era of potent combination anti-retroviral therapy

31 March 2020

1 reference

Long-term efficacy on Kaposi's sarcoma of highly active antiretroviral therapy in a cohort of HIV-positive patients

31 March 2020

1 reference

Improved outcome of AIDS-related lymphoma in patients with virologic response to highly active antiretroviral therapy

31 March 2020

1 reference

Clearance of human herpesvirus type 8 viraemia in HIV-1-positive patients with Kaposi's sarcoma treated with liposomal doxorubicin. Caelyx/KS Spanish Study Group.

31 March 2020

1 reference

Reduction of Kaposi's sarcoma lesions following treatment of AIDS with ritonovir

31 March 2020

1 reference

Response of AIDS-associated Kaposi sarcoma to highly active antiretroviral therapy alone

31 March 2020

1 reference

Regression of Invasive AIDS‐Related Kaposi's Sarcoma Following Antiretroviral Therapy

31 March 2020

1 reference

Evaluation of the human herpesvirus 8 DNA load in blood and Kaposi's sarcoma skin lesions from AIDS patients on highly active antiretroviral therapy

31 March 2020

1 reference

Complete histological regression of Kaposi's sarcoma following treatment with protease inhibitors despite persistence of HHV-8 in lesions

31 March 2020

1 reference

Human papillomavirus type 16 in cervical smears as predictor of high-grade cervical intraepithelial neoplasia [corrected]

31 March 2020

1 reference

The presence of persistent high-risk HPV genotypes in dysplastic cervical lesions is associated with progressive disease: natural history up to 36 months

31 March 2020

1 reference

Evidence for the existence of a non-catalytic modifier site of peptide hydrolysis by the 20 S proteasome

31 March 2020

1 reference

Intact vitronectin induces matrix metalloproteinase-2 and tissue inhibitor of metalloproteinases-2 expression and enhanced cellular invasion by melanoma cells

31 March 2020

1 reference

Bone mineral loss through increased bone turnover in HIV-infected children treated with highly active antiretroviral therapy

31 March 2020

1 reference

The role of COX-2 inhibition in breast cancer treatment and prevention

31 March 2020

1 reference

PR39, a peptide regulator of angiogenesis

31 March 2020

1 reference

The proteasome is involved in angiogenesis

31 March 2020

1 reference

31 March 2020

1 reference

Phase I study of cisdiamminedichloroplatinum in combination with azidothymidine in the treatment of patients with advanced malignancies

31 March 2020

1 reference

7 January 2021

inferred from DOI database lookup

Differential susceptibility of naive and memory CD4+ T cells to the cytopathic effects of infection with human immunodeficiency virus type 1 strain LAI.

1 reference

7 January 2021

inferred from DOI database lookup

HAART is effective as anti-Kaposi's sarcoma therapy only after remission has been induced by chemotherapy

1 reference

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/NRC1479

1 reference

release_xvlwgextfje2rhsd6qaj4ubugy

11 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/xvlwgextfje2rhsd6qaj4ubugy

24 November 2022

mapped directly with Wikidata item

1 reference