Strategies to enhance T-cell reconstitution in immunocompromised patients (Q35934161)

11 August 2017

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title

Strategies to enhance T-cell reconstitution in immunocompromised patients (English)

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11 August 2017

Marcel R M van den Brink

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11 August 2017

Onder Alpdogan

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2

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11 August 2017

Richard L Boyd

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3

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11 August 2017

1 November 2004

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Nature Reviews Immunology

11 August 2017

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11 August 2017

4

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11 August 2017

11

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11 August 2017

856-867

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https://scigraph.springernature.com/pub.10.1038/nri1484

11 August 2017

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Myeloid progenitors protect against invasive aspergillosis and Pseudomonas aeruginosa infection following hematopoietic stem cell transplantation

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Common lymphoid progenitors rapidly engraft and protect against lethal murine cytomegalovirus infection after hematopoietic stem cell transplantation.

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Composite "thymoheart" transplantation improves cardiac allograft survival

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The nu gene acts cell-autonomously and is required for differentiation of thymic epithelial progenitors.

31 March 2020

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Generation of a complete thymic microenvironment by MTS24(+) thymic epithelial cells

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Identification and Characterization of Thymic Epithelial Progenitor Cells

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Development of cytolytic T lymphocyte precursors in organ-cultured mouse embryonic thymus rudiments

31 March 2020

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Efficient generation of human T cells from a tissue-engineered thymic organoid

31 March 2020

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Extrathymic T cell differentiation in vitro from human CD34+ stem cells

31 March 2020

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Notch regulation of lymphocyte development and function.

31 March 2020

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Microenvironmental regulation of Notch signalling in T cell development.

31 March 2020

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Induction of T cell development from hematopoietic progenitor cells by delta-like-1 in vitro.

31 March 2020

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Combined effects of Notch signaling and cytokines induce a multiple log increase in precursors with lymphoid and myeloid reconstituting ability.

31 March 2020

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T-cell development made simple

31 March 2020

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Thymic atrophy in the mouse is a soluble problem of the thymic environment.

31 March 2020

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Ultrastructural study of thymic microenvironment involution in aging mice

31 March 2020

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Evaluation of thymopoiesis using T cell receptor excision circles (TRECs): differential correlation between adult and pediatric TRECs and naïve phenotypes

31 March 2020

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31 March 2020

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Reappearance of thymus of ageing rats after orchidectomy

31 March 2020

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Regeneration of the thymus in old male rats treated with a stable analogue of LHRH

31 March 2020

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Effects of castration on the lymphocytes of the thymus, spleen and lymph nodes.

31 March 2020

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Orchidectomy and the immune response. II. Response of orchidectomized mice to antigens.

31 March 2020

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Insulin-like growth factor-1 stimulation of lymphopoiesis

31 March 2020

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Growth hormone as an immunomodulating therapeutic agent

31 March 2020

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Insulin-Like Growth Factor-I Binds Selectively to Human Peripheral Blood Monocytes and B-Lymphocytes*

31 March 2020

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The insulin-like growth factor-I receptor is regulated by CD28 and protects activated T cells from apoptosis

31 March 2020

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Regulation of B and T cell development by anterior pituitary hormones.

31 March 2020

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Recombinant human growth hormone promotes hematopoietic reconstitution after syngeneic bone marrow transplantation in mice.

31 March 2020

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Insulin-like growth factor-I enhances lymphoid and myeloid reconstitution after allogeneic bone marrow transplantation

31 March 2020

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Immunologic and hematopoietic effects of recombinant human prolactin after syngeneic bone marrow transplantation in mice

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Keratinocyte growth factor induces proliferation of hepatocytes and epithelial cells throughout the rat gastrointestinal tract

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Stimulation of all epithelial elements during skin regeneration by keratinocyte growth factor.

31 March 2020

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Protection from thymic epithelial cell injury by keratinocyte growth factor: a new approach to improve thymic and peripheral T-cell reconstitution after bone marrow transplantation

31 March 2020

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Regulation of thymic epithelium by keratinocyte growth factor

31 March 2020

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Development of the thymus requires signaling through the fibroblast growth factor receptor R2-IIIb

31 March 2020

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Keratinocyte growth factor preserves normal thymopoiesis and thymic microenvironment during experimental graft-versus-host disease

31 March 2020

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Randomized Phase I Trial of Recombinant Human Keratinocyte Growth Factor Plus Chemotherapy: Potential Role as Mucosal Protectant

31 March 2020

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IL-2, regulatory T cells, and tolerance

31 March 2020

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High-producer interleukin-2 genotype increases risk for acute graft-versus-host disease after unrelated donor bone marrow transplantation

31 March 2020

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T lymphocytes potentiate murine dendritic cells to produce IL-12

31 March 2020

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IL-12 inhibits thymic involution by enhancing IL-7- and IL-2-induced thymocyte proliferation

31 March 2020

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Interleukin-7: from bench to clinic

31 March 2020

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Interleukin-2 receptor gamma chain: a functional component of the interleukin-7 receptor

31 March 2020

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Cloning of the human and murine interleukin-7 receptors: demonstration of a soluble form and homology to a new receptor superfamily

31 March 2020

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Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine.

31 March 2020

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Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient mice

31 March 2020

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The earliest T lineage-committed cells depend on IL-7 for Bcl-2 expression and normal cell cycle progression

31 March 2020

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Bcl-2 rescues T lymphopoiesis in interleukin-7 receptor-deficient mice

31 March 2020

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Interleukin-7 mediates the homeostasis of naïve and memory CD8 T cells in vivo

31 March 2020

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Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells.

31 March 2020

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IL-7 enhances peripheral T cell reconstitution after allogeneic hematopoietic stem cell transplantation

31 March 2020

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T cell receptor excision circle assessment of thymopoiesis in aging mice

31 March 2020

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Effects of exogenous interleukin-7 on human thymus function

31 March 2020

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IL-7 administration alters the CD4:CD8 ratio, increases T cell numbers, and increases T cell function in the absence of activation

31 March 2020

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Interleukin 7 promotes long-term in vitro growth of antitumor cytotoxic T lymphocytes with immunotherapeutic efficacy in vivo

31 March 2020

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Augmentation of cell-mediated immunotherapy against herpes simplex virus by interleukins: comparison of in vivo effects of IL-2 and IL-7 on adoptively transferred T cells

31 March 2020

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Administration of interleukin-7 after allogeneic bone marrow transplantation improves immune reconstitution without aggravating graft-versus-host disease

31 March 2020

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IL-7 increases both thymic-dependent and thymic-independent T-cell regeneration after bone marrow transplantation

31 March 2020

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Interleukin 7 worsens graft-versus-host disease

31 March 2020

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Interleukin-7 improves CD4 T-cell reconstitution after autologous CD34 cell transplantation in monkeys

31 March 2020

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Interleukin 15: biology and relevance to human disease

31 March 2020

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Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice

31 March 2020

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IL-15 receptor maintains lymphoid homeostasis by supporting lymphocyte homing and proliferation

31 March 2020

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Interleukin (IL) 15 is a novel cytokine that activates human natural killer cells via components of the IL-2 receptor

31 March 2020

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A potential role for interleukin-15 in the regulation of human natural killer cell survival

31 March 2020

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Potent and selective stimulation of memory-phenotype CD8+ T cells in vivo by IL-15.

31 March 2020

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Interleukin-7 or interleukin-15 enhances survival of Mycobacterium tuberculosis-infected mice

31 March 2020

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Memory phenotype CD8(+) T cells in IL-15 transgenic mice are involved in early protection against a primary infection with Listeria monocytogenes.

31 March 2020

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IL-15 enhances the in vivo antitumor activity of tumor-reactive CD8+ T cells

31 March 2020

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IL-15 administration following syngeneic bone marrow transplantation prolongs survival of lymphoma bearing mice

31 March 2020

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Interleukin-15 enhances immune reconstitution after allogeneic bone marrow transplantation

31 March 2020

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Studies evaluating the antitumor activity and toxicity of interleukin-15, a new T cell growth factor: comparison with interleukin-2

31 March 2020

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Mature dendritic cells can enhance CD8+ cell noncytotoxic anti-HIV responses: the role of IL-15.

31 March 2020

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CD28-mediated co-stimulation: a quantitative support for TCR signalling

31 March 2020

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Rapid recovery from T lymphopenia by CD28 superagonist therapy

31 March 2020

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Efficient expansion of regulatory T cells in vitro and in vivo with a CD28 superagonist

31 March 2020

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Cutting edge: distinct TCR- and CD28-derived signals regulate CD95L, Bcl-xL, and the survival of primary T cells

31 March 2020

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Regulation of an extrathymic T-cell development pathway by oncostatin M

31 March 2020

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Leukemia inhibitory factor, oncostatin M, IL-6, and stem cell factor mRNA expression in human thymus increases with age and is associated with thymic atrophy

31 March 2020

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Pathways of T-cell regeneration in mice and humans: implications for bone marrow transplantation and immunotherapy

31 March 2020

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Dynamics of early T cells: prothymocyte migration and proliferation in the adult mouse thymus

31 March 2020

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The importation of hematogenous precursors by the thymus is a gated phenomenon in normal adult mice

31 March 2020

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Role of thymic organ structure and stromal composition in steady-state postnatal T-cell production

31 March 2020

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Early T lineage progenitors: new insights, but old questions remain

31 March 2020

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Identification of clonogenic common lymphoid progenitors in mouse bone marrow

31 March 2020

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Efficient thymic immigration of B220+ lymphoid-restricted bone marrow cells with T precursor potential.

31 March 2020

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Thymopoiesis independent of common lymphoid progenitors

31 March 2020

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Key role of flt3 ligand in regulation of the common lymphoid progenitor but not in maintenance of the hematopoietic stem cell pool

31 March 2020

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Transcription from the RAG1 locus marks the earliest lymphocyte progenitors in bone marrow

31 March 2020

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L-selectin defines a bone marrow analog to the thymic early T-lineage progenitor

31 March 2020

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Peripheral T lymphocytes: expansion potential and homeostatic regulation of pool sizes and CD4/CD8 ratios in vivo

31 March 2020

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Control of homeostasis of CD8+ memory T cells by opposing cytokines.

31 March 2020

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The organization of mature T-cell pools

31 March 2020

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Peripheral T cell survival

31 March 2020

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Selecting and maintaining a diverse T-cell repertoire

31 March 2020

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Designing and maintaining the mature TCR repertoire: the continuum of self-peptide:self-MHC complex recognition

31 March 2020

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The effect of graft-versus-host disease on T cell production and homeostasis

31 March 2020

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IL-7 is critical for homeostatic proliferation and survival of naive T cells

31 March 2020

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Cytokine requirements for acute and Basal homeostatic proliferation of naive and memory CD8+ T cells

31 March 2020

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Interleukin 7 and T cell receptor signals regulate homeostasis of CD4 memory cells

31 March 2020

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IL-15 induces antigen-independent expansion and differentiation of human naive CD8+ T cells in vitro.

31 March 2020

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Interleukin (IL)-15 and IL-7 jointly regulate homeostatic proliferation of memory phenotype CD8+ cells but are not required for memory phenotype CD4+ cells

31 March 2020

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The transcription factor NFAT4 is involved in the generation and survival of T cells

31 March 2020

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LKLF: A transcriptional regulator of single-positive T cell quiescence and survival

31 March 2020

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Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair

31 March 2020

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Growth hormone restores glucocorticoid-induced T cell suppression

31 March 2020

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inferred from DOI database lookup

7 January 2021

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Identifiers

DOI

10.1038/NRI1484

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Dimensions Publication ID

11 August 2017

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