RNA-based gene therapy for HIV with lentiviral vector-modified CD34(+) cells in patients undergoing transplantation for AIDS-related lymphoma (Q34121209)

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English	RNA-based gene therapy for HIV with lentiviral vector-modified CD34(+) cells in patients undergoing transplantation for AIDS-related lymphoma	scientific article

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scholarly article

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Europe PubMed Central

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31 July 2017

RNA-based gene therapy for HIV with lentiviral vector-modified CD34(+) cells in patients undergoing transplantation for AIDS-related lymphoma (English)

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31 July 2017

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primary effusion lymphoma

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Simon F Lacey

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David L. Digiusto

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David L DiGiusto

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Anitha Rao

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Joseph Alvarnas

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Joseph Alvarnas

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Amrita Krishnan

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31 July 2017

Lijing Li

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Haitang Li

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Shirley Li

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Shu Mi

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Priscilla Yam

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Sherri Stinson

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Michael Kalos

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Jiing-Kuan Yee

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Mingjie Li

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Larry Couture

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David Hsu

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Stephen J Forman

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John J Rossi

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John A Zaia

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publication date

1 June 2010

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31 July 2017

Science Translational Medicine

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2

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36

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36ra43

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31 July 2017

Hematopoietic stem cell gene therapy with a lentiviral vector in X-linked adrenoleukodystrophy

1 reference

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5 July 2018

Chemoprotection of human hematopoietic stem cells by simultaneous lentiviral overexpression of multidrug resistance 1 and O(6)-methylguanine-DNA methyltransferase(P140K).

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5 July 2018

The challenge of finding a cure for HIV infection

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130552

5 July 2018

Analysis of lentiviral vector integration in HIV+ study subjects receiving autologous infusions of gene modified CD4+ T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130552

5 July 2018

Phase 2 gene therapy trial of an anti-HIV ribozyme in autologous CD34+ cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130552

5 July 2018

Long-term control of HIV by CCR5 Delta32/Delta32 stem-cell transplantation

1 reference

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5 July 2018

Engineering and optimization of the miR-106b cluster for ectopic expression of multiplexed anti-HIV RNAs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130552

5 July 2018

Fusion of Epstein-Barr virus nuclear antigen-1-derived glycine-alanine repeat to trans-dominant HIV-1 Gag increases inhibitory activities and survival of transduced cells in vivo

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130552

5 July 2018

Genetic therapies against HIV.

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5 July 2018

Lentivirus vectors expressing short hairpin RNAs against the U3-overlapping region of HIV nef inhibit HIV replication and infectivity in primary macrophages

1 reference

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5 July 2018

Optimization and functional effects of stable short hairpin RNA expression in primary human lymphocytes via lentiviral vectors.

1 reference

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5 July 2018

Distribution of health care expenditures for HIV-infected patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130552

5 July 2018

Integration site selection by HIV-based vectors in dividing and growth-arrested IMR-90 lung fibroblasts.

1 reference

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5 July 2018

Survival of the fittest: in vivo selection and stem cell gene therapy

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5 July 2018

T Lymphocytes transduced with a lentiviral vector expressing F12-Vif are protected from HIV-1 infection in an APOBEC3G-independent manner.

1 reference

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5 July 2018

Suppression of HIV-1 infection in primary CD4 T cells transduced with a self-inactivating lentiviral vector encoding a membrane expressed gp41-derived fusion inhibitor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130552

5 July 2018

Expression of HIV-1 integrase in CEM cells inhibits HIV-1 replication

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130552

5 July 2018

Inhibition of HIV-1 infection by lentiviral vectors expressing Pol III-promoted anti-HIV RNAs.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130552

5 July 2018

Inhibition of HIV-1 by lentiviral vector-transduced siRNAs in T lymphocytes differentiated in SCID-hu mice and CD34+ progenitor cell-derived macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130552

5 July 2018

Design of HIV vectors for efficient gene delivery into human hematopoietic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130552

5 July 2018

Transduction of human progenitor hematopoietic stem cells by human immunodeficiency virus type 1-based vectors is cell cycle dependent.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130552

5 July 2018

RevM10-expressing T cells derived in vivo from transduced human hematopoietic stem-progenitor cells inhibit human immunodeficiency virus replication

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130552

5 July 2018

Sustained retroviral gene marking and expression in lymphoid and myeloid cells derived from transduced hematopoietic progenitor cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130552

5 July 2018

Leukemia inhibitory factor upregulates cytokine expression by a murine stromal cell line enabling the maintenance of highly enriched competitive repopulating stem cells.

1 reference

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5 July 2018

In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130552

5 July 2018

A predictive model for aggressive non-Hodgkin's lymphoma. The International Non-Hodgkin's Lymphoma Prognostic Factors Project

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130552

5 July 2018

Human fetal bone marrow early progenitors for T, B, and myeloid cells are found exclusively in the population expressing high levels of CD34.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130552

5 July 2018

Gene therapy. Intracellular immunization

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5 July 2018

Inhibition of human immunodeficiency virus type 1 replication in human T cells by retroviral-mediated gene transfer of a dominant-negative Rev trans-activator

1 reference

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5 July 2018

Development and characterization of a triple combination gene therapy vector inhibiting HIV-1 multiplication

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3000931

21 January 2018

Nonmyeloablative conditioning followed by transplantation of genetically modified HLA-matched peripheral blood progenitor cells for hematologic malignancies in patients with acquired immunodeficiency syndrome

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3000931

21 January 2018

Selective survival of peripheral blood lymphocytes in children with HIV-1 following delivery of an anti-HIV gene to bone marrow CD34(+) cells

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3000931

21 January 2018

Anti-human immunodeficiency virus hematopoietic progenitor cell-delivered ribozyme in a phase I study: myeloid and lymphoid reconstitution in human immunodeficiency virus type-1-infected patients

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3000931

21 January 2018

Durable remissions with autologous stem cell transplantation for high-risk HIV-associated lymphomas

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https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3000931

21 January 2018

Lentiviruses in gene therapy clinical research

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https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3000931

21 January 2018

Long-term inhibition of HIV-1 infection in primary hematopoietic cells by lentiviral vector delivery of a triple combination of anti-HIV shRNA, anti-CCR5 ribozyme, and a nucleolar-localizing TAR decoy

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3000931

21 January 2018

Production of lentiviruses displaying ''early-acting'' cytokines for selective gene transfer into hematopoietic stem cells.

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3000931

21 January 2018

Cytokines, including stem cell factor alone, enhance lentiviral transduction in nondividing human LTCIC and NOD/SCID repopulating cells

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3000931

21 January 2018

Transient in vivo selection of transduced peripheral blood cells using antifolate drug selection in rhesus macaques that received transplants with hematopoietic stem cells expressing dihydrofolate reductase vectors.

1 reference

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21 January 2018

In vivo selective expansion of gene-modified hematopoietic cells in a nonhuman primate model.

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3000931

21 January 2018

Safety and efficacy of a lentiviral vector containing three anti-HIV genes--CCR5 ribozyme, tat-rev siRNA, and TAR decoy--in SCID-hu mouse-derived T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130552

28 October 2018

Identifiers

10.1126/SCITRANSLMED.3000931

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

PMC publication ID

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Europe PubMed Central

PubMed publication ID

31 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

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