An attenuated strain of enterovirus 71 belonging to genotype a showed a broad spectrum of antigenicity with attenuated neurovirulence in cynomolgus monkeys. (Q35948053)

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English	An attenuated strain of enterovirus 71 belonging to genotype a showed a broad spectrum of antigenicity with attenuated neurovirulence in cynomolgus monkeys.	scientific article

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31 December 2019

An attenuated strain of enterovirus 71 belonging to genotype a showed a broad spectrum of antigenicity with attenuated neurovirulence in cynomolgus monkeys (English)

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Tetsutarō Sata

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Tetsutaro Sata

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Noriyo Nagata

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Naoko Iwata

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Yasushi Ami

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Yuriko Suzaki

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Katsumi Mizuta

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Takuya Iwasaki

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Takaji Wakita

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Hiroyuki Shimizu

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13 June 2007

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31 December 2019

Journal of Virology

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9386-9395

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31 December 2019

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31 December 2019

Quantitative analysis of poliomyelitis-like paralysis in mice induced by a poliovirus replicon.

1 reference

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Reduction of the rate of poliovirus protein synthesis through large-scale codon deoptimization causes attenuation of viral virulence by lowering specific infectivity

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Rational design of genetically stable, live-attenuated poliovirus vaccines of all three serotypes: relevance to poliomyelitis eradication

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2 October 2017

Modulation of poliovirus replicative fitness in HeLa cells by deoptimization of synonymous codon usage in the capsid region.

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Virus perpetuation in populations: biological variables that determine persistence or eradication

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2 October 2017

Frequent importation of enterovirus 71 from surrounding countries into the local community of Yamagata, Japan, between 1998 and 2003.

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2 October 2017

Mutation of a single conserved nucleotide between the cloverleaf and internal ribosome entry site attenuates poliovirus neurovirulence

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2 October 2017

Genetic characteristics of human enterovirus 71 and coxsackievirus A16 circulating from 1999 to 2004 in Shenzhen, People's Republic of China

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2 October 2017

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2 October 2017

Pathogenesis of poliomyelitis; reappraisal in the light of new data

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2 October 2017

Enterovirus 71 outbreaks, Taiwan: occurrence and recognition

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2 October 2017

An overview of the evolution of enterovirus 71 and its clinical and public health significance

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2 October 2017

Change of major genotype of enterovirus 71 in outbreaks of hand-foot-and-mouth disease in Taiwan between 1998 and 2000.

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2 October 2017

Phylogenetic analysis of enterovirus 71 strains isolated during linked epidemics in Malaysia, Singapore, and Western Australia

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2 October 2017

Enterovirus 71 from fatal and nonfatal cases of hand, foot and mouth disease epidemics in Malaysia, Japan and Taiwan in 1997-1998.

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2 October 2017

Molecular epidemiology and evolution of enterovirus 71 strains isolated from 1970 to 1998

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2 October 2017

Neurologic complications in children with enterovirus 71 infection

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2 October 2017

An epidemic of enterovirus 71 infection in Taiwan. Taiwan Enterovirus Epidemic Working Group.

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2 October 2017

Interaction of poliovirus with its receptor affords a high level of infectivity to the virion in poliovirus infections mediated by the Fc receptor

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2 October 2017

Dual stem loops within the poliovirus internal ribosomal entry site control neurovirulence

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2 October 2017

Complete nucleotide sequence of enterovirus 71 is distinct from poliovirus

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2 October 2017

A mutation in the RNA polymerase of poliovirus type 1 contributes to attenuation in mice.

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2 October 2017

Construction and genetic analysis of dicistronic polioviruses containing open reading frames for epitopes of human immunodeficiency virus type 1 gp120.

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2 October 2017

Virus aggregation as the cause of the non-neutralizable persistent fraction

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2 October 2017

Genetic analysis of the attenuation phenotype of poliovirus type 1.

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2 October 2017

Construction of less neurovirulent polioviruses by introducing deletions into the 5' noncoding sequence of the genome.

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2 October 2017

Determinants in the 5' noncoding region of poliovirus Sabin 1 RNA that influence the attenuation phenotype

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2 October 2017

The epidemiology of poliomyelitis: enigmas surrounding its appearance, epidemicity, and disappearance

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2 October 2017

Epidemiological, clinical, and pathomorphological characteristics of epidemic poliomyelitis-like disease caused by enterovirus 71

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2 October 2017

Enterovirus 71 isolated from cases of epidemic poliomyelitis-like disease in Bulgaria

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2 October 2017

Epidemic of Hand, Foot and Mouth Disease Associated with Enterovirus 71 Infection

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2 October 2017

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An apparently new enterovirus isolated from patients with disease of the central nervous system

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Temperature-sensitive mutants of enterovirus 71 show attenuation in cynomolgus monkeys.

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Differential localization of neurons susceptible to enterovirus 71 and poliovirus type 1 in the central nervous system of cynomolgus monkeys after intravenous inoculation

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Pathogenesis of enterovirus 71 brainstem encephalitis in pediatric patients: roles of cytokines and cellular immune activation in patients with pulmonary edema.

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Outbreak of central nervous system disease associated with hand, foot, and mouth disease in Japan during the summer of 2000: detection and molecular epidemiology of enterovirus 71.

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24 September 2018

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Incidence and case-fatality rates resulting from the 1998 enterovirus 71 outbreak in Taiwan

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24 September 2018

Pyramidal and extrapyramidal involvement in experimental infection of cynomolgus monkeys with enterovirus 71.

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24 September 2018

Clinical spectrum of enterovirus 71 infection in children in southern Taiwan, with an emphasis on neurological complications.

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24 September 2018

Outbreak of severe neurologic involvement associated with Enterovirus 71 infection

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24 September 2018

Fatal enterovirus 71 encephalomyelitis.

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24 September 2018

Molecular comparison of coxsackie A virus serotypes

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24 September 2018

Comparative studies on the neurovirulence of temperature-sensitive and temperature-resistant viruses of enterovirus 71 in monkeys

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24 September 2018

Evolution of EV71 genogroup in Taiwan from 1998 to 2005: An emerging of subgenogroup C4 of EV71

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24 September 2018

Pathogenicity of a poliomyelitis-like disease in monkeys infected orally with enterovirus 71: a model for human infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/17567701

12 December 2020

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Clinical features and risk factors of pulmonary oedema after enterovirus-71-related hand, foot, and mouth disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17567701

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based on heuristic

inferred from PubMed ID database lookup

The molecular biology of poliovaccines

1 reference

https://pubmed.ncbi.nlm.nih.gov/17567701

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based on heuristic

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Molecular epidemiology of enterovirus 71 infection in the Western Pacific Region

1 reference

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The antigenic heterogeneity of type 30 echoviruses

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Oral poliovirus vaccine. History of its development and prospects for eradication of poliomyelitis

1 reference

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inferred from PubMed ID database lookup

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10.1128/JVI.02856-06

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31 December 2019

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31 December 2019

1 reference

Europe PubMed Central

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31 December 2019

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