Co-Expression of Wild-Type P2X7R with Gln460Arg Variant Alters Receptor Function (Q35961235)

11 August 2017

Co-Expression of Wild-Type P2X7R with Gln460Arg Variant Alters Receptor Function (English)

1 reference

11 August 2017

14

Florian Holsboer

0 references

Miso Mitkovski

object named as

Mišo Mitkovski

11

0 references

Jan M. Deussing

object named as

Jan M Deussing

15

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author name string

Fernando Aprile-Garcia

1

1 reference

11 August 2017

Michael W Metzger

2

1 reference

11 August 2017

Marcelo Paez-Pereda

3

1 reference

11 August 2017

Herbert Stadler

4

1 reference

11 August 2017

Matías Acuña

5

1 reference

11 August 2017

Ana C Liberman

6

1 reference

11 August 2017

Sergio A Senin

7

1 reference

11 August 2017

Juan Gerez

8

1 reference

11 August 2017

Esteban Hoijman

9

1 reference

11 August 2017

Damian Refojo

10

1 reference

11 August 2017

Markus Panhuysen

12

1 reference

11 August 2017

Walter Stühmer

13

1 reference

11 August 2017

Eduardo Arzt

16

1 reference

11 August 2017

language of work or name

English

0 references

publication date

17 March 2016

1 reference

11 August 2017

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11 August 2017

11

1 reference

11 August 2017

3

1 reference

11 August 2017

e0151862

1 reference

Creative Commons Attribution 4.0 International

11 August 2017

start time

17 March 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4795689/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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P2X7 receptor activation induces reactive oxygen species formation and cell death in murine EOC13 microglia

2 October 2017

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Single nucleotide polymorphisms that were identified in affective mood disorders affect ATP-activated P2X7 receptor functions

2 October 2017

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Point mutation in the mouse P2X7 receptor affects intercellular calcium waves in astrocytes

2 October 2017

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Activation of P2X7 receptors induces CCL3 production in microglial cells through transcription factor NFAT

2 October 2017

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2 October 2017

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2 October 2017

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Polymorphisms in inflammation-related genes are associated with susceptibility to major depression and antidepressant response

2 October 2017

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From inflammation to sickness and depression: when the immune system subjugates the brain

2 October 2017

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In vitro and in vivo evidence for a role of the P2X7 receptor in the release of IL-1 beta in the murine brain

2 October 2017

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Evidence for functional P2X4/P2X7 heteromeric receptors

2 October 2017

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2 October 2017

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P2X receptors as cell-surface ATP sensors in health and disease

2 October 2017

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P2X7 receptors in the nervous system

2 October 2017

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A truncated P2X7 receptor variant (P2X7-j) endogenously expressed in cervical cancer cells antagonizes the full-length P2X7 receptor through hetero-oligomerization

2 October 2017

1 reference

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Astrocyte dysfunction in neurological disorders: a molecular perspective

2 October 2017

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PixFRET, an ImageJ plug-in for FRET calculation that can accommodate variations in spectral bleed-throughs

2 October 2017

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A His-155 to Tyr polymorphism confers gain-of-function to the human P2X7 receptor of human leukemic lymphocytes.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4795689

An Arg307 to Gln polymorphism within the ATP-binding site causes loss of function of the human P2X7 receptor.

2 October 2017

1 reference

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Subunit Arrangement in P2X Receptors

2 October 2017

1 reference

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P2X7 nucleotide receptor activation enhances IFN gamma-induced type II nitric oxide synthase activity in BV-2 microglial cells

2 October 2017

1 reference

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An Ile-568 to Asn polymorphism prevents normal trafficking and function of the human P2X7 receptor

2 October 2017

1 reference

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Reliable and global measurement of fluorescence resonance energy transfer using fluorescence microscopes

2 October 2017

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Neuronal P2X7 receptors are targeted to presynaptic terminals in the central and peripheral nervous systems

2 October 2017

1 reference

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A Glu-496 to Ala polymorphism leads to loss of function of the human P2X7 receptor

2 October 2017

1 reference

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Cytokines and the brain: implications for clinical psychiatry

2 October 2017

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Purinergic modulation of interleukin-1 beta release from microglial cells stimulated with bacterial endotoxin

2 October 2017

1 reference

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The cytolytic P2Z receptor for extracellular ATP identified as a P2X receptor (P2X7)

2 October 2017

1 reference

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P2X4 receptors interact with both P2X2 and P2X7 receptors in the form of homotrimers

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4795689

Inter-subunit disulfide cross-linking in homomeric and heteromeric P2X receptors

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4795689

The P2X7/P2X4 interaction shapes the purinergic response in murine macrophages.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4795689

Associations between depression severity and purinergic receptor P2RX7 gene polymorphisms.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4795689

P2RX7 gene is associated consistently with mood disorders and predicts clinical outcome in three clinical cohorts

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4795689

P2RX7 polymorphisms Gln460Arg and His155Tyr are not associated with major depressive disorder or remission after SSRI or ECT.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4795689

Variation in P2RX7 candidate gene (rs2230912) is not associated with bipolar I disorder and unipolar major depression in four European samples

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4795689

The P2X7 receptor drives microglial activation and proliferation: a trophic role for P2X7R pore

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4795689

P2RX7: A bipolar and unipolar disorder candidate susceptibility gene?

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4795689

Homotrimeric complexes are the dominant assembly state of native P2X7 subunits

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4795689

P2RX7 Gln460Arg polymorphism is associated with depression among diabetic patients

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4795689

Association between depression and the Gln460Arg polymorphism of P2RX7 gene: a dimensional approach

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4795689

Case-control studies show that a non-conservative amino-acid change from a glutamine to arginine in the P2RX7 purinergic receptor protein is associated with both bipolar- and unipolar-affective disorders

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4795689

P2RX7, a gene coding for a purinergic ligand-gated ion channel, is associated with major depressive disorder

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4795689

Extracellular ATP induces cytokine expression and apoptosis through P2X7 receptor in murine mast cells

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4795689

A loss-of-function polymorphism in the human P2X7 receptor abolishes ATP-mediated killing of mycobacteria.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4795689

Potentiation by ATP of lipopolysaccharide-stimulated nitric oxide production in cultured astrocytes

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4795689

Mechanisms of P2X7 receptor-mediated ERK1/2 phosphorylation in human astrocytoma cells

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4795689

P2X7-like receptor activation in astrocytes increases chemokine monocyte chemoattractant protein-1 expression via mitogen-activated protein kinase.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4795689

Kinetics of cell lysis, dye uptake and permeability changes in cells expressing the rat P2X7 receptor.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4795689

Single nucleotide polymorphisms in the P2X7 gene are associated to fracture risk and to effect of estrogen treatment

24 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0151862

Analysis of single nucleotide polymorphisms in genes in the chromosome 12Q24.31 region points to P2RX7 as a susceptibility gene to bipolar affective disorder

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26986975

12 December 2020

inferred from PubMed ID database lookup

P2X7-dependent, but differentially regulated release of IL-6, CCL2, and TNF-α in cultured mouse microglia

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26986975

12 December 2020

inferred from PubMed ID database lookup

Interleukin (IL)-6, tumour necrosis factor alpha (TNF-α) and soluble interleukin-2 receptors (sIL-2R) are elevated in patients with major depressive disorder: a meta-analysis and meta-regression

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26986975

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1371/JOURNAL.PONE.0151862

1 reference

11 August 2017

0 references

1 reference

11 August 2017

PubMed publication ID

26986975

1 reference