Increased nuclear suppressor of cytokine signaling 1 in asthmatic bronchial epithelium suppresses rhinovirus induction of innate interferons (Q35971340)

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English	Increased nuclear suppressor of cytokine signaling 1 in asthmatic bronchial epithelium suppresses rhinovirus induction of innate interferons	scientific article

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28 February 2020

Increased nuclear suppressor of cytokine signaling 1 in asthmatic bronchial epithelium suppresses rhinovirus induction of innate interferons (English)

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28 February 2020

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Amelia Shoemark

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28 February 2020

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28 February 2020

Sebastian L Johnston

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28 February 2020

Alexander Dalpke

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Alexander H Dalpke

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28 February 2020

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Sejal Saglani

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28 February 2020

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Vera Gielen

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28 February 2020

Annemarie Sykes

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28 February 2020

Jie Zhu

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28 February 2020

Brian Chan

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28 February 2020

Jonathan Macintyre

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28 February 2020

Nicolas Regamey

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28 February 2020

Elisabeth Kieninger

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28 February 2020

Atul Gupta

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28 February 2020

Cara Bossley

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28 February 2020

Jane Davies

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28 February 2020

Patrick Walker

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28 February 2020

Sandra E Nicholson

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28 February 2020

Andrew Bush

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28 February 2020

Michael R Edwards

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25 January 2015

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28 February 2020

The Journal of Allergy and Clinical Immunology

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28 February 2020

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28 February 2020

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28 February 2020

Viral and host factors determine innate immune responses in airway epithelial cells from children with wheeze and atopy

1 reference

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2 October 2017

Impaired innate interferon induction in severe therapy resistant atopic asthmatic children

1 reference

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2 October 2017

Defining critical roles for NF-κB p65 and type I interferon in innate immunity to rhinovirus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4541718

2 October 2017

Transforming growth factor-beta promotes rhinovirus replication in bronchial epithelial cells by suppressing the innate immune response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4541718

2 October 2017

Innate immune responses to rhinovirus are reduced by the high-affinity IgE receptor in allergic asthmatic children

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4541718

2 October 2017

Lebrikizumab treatment in adults with asthma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4541718

2 October 2017

Suppressor of cytokine signaling (SOCS) 1 inhibits type I interferon (IFN) signaling via the interferon alpha receptor (IFNAR1)-associated tyrosine kinase Tyk2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4541718

2 October 2017

SOCS2 regulates T helper type 2 differentiation and the generation of type 2 allergic responses.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4541718

2 October 2017

Suppressor of cytokine signaling 1 (SOCS1) limits NFkappaB signaling by decreasing p65 stability within the cell nucleus

1 reference

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2 October 2017

Counterregulation between the FcepsilonRI pathway and antiviral responses in human plasmacytoid dendritic cells

1 reference

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2 October 2017

Structural and functional analysis of a nuclear localization signal in SOCS1.

1 reference

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2 October 2017

Suppressor of cytokine signalling 1 (SOCS1) is a physiological regulator of the asthma response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4541718

2 October 2017

Respiratory virus induction of alpha-, beta- and lambda-interferons in bronchial epithelial cells and peripheral blood mononuclear cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4541718

2 October 2017

Rhinovirus-induced lower respiratory illness is increased in asthma and related to virus load and Th1/2 cytokine and IL-10 production

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4541718

2 October 2017

Cutting edge: innate immune response triggered by influenza A virus is negatively regulated by SOCS1 and SOCS3 through a RIG-I/IFNAR1-dependent pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4541718

2 October 2017

Mouse models of rhinovirus-induced disease and exacerbation of allergic airway inflammation

1 reference

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2 October 2017

IFN regulatory factor family members differentially regulate the expression of type III IFN (IFN-lambda) genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4541718

2 October 2017

Asthmatic bronchial epithelial cells have a deficient innate immune response to infection with rhinovirus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4541718

2 October 2017

SOCS-1 and SOCS-3 inhibit IFN-alpha-induced expression of the antiviral proteins 2,5-OAS and MxA.

1 reference

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2 October 2017

Suppressors of cytokine signaling proteins are differentially expressed in Th1 and Th2 cells: implications for Th cell lineage commitment and maintenance

1 reference

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2 October 2017

SOCS-1/SSI-1-deficient NKT cells participate in severe hepatitis through dysregulated cross-talk inhibition of IFN-gamma and IL-4 signaling in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4541718

2 October 2017

Rhinovirus infection induces expression of its own receptor intercellular adhesion molecule 1 (ICAM-1) via increased NF-kappaB-mediated transcription.

1 reference

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2 October 2017

Differential viral induction of distinct interferon-alpha genes by positive feedback through interferon regulatory factor-7

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2 October 2017

Community study of role of viral infections in exacerbations of asthma in 9-11 year old children

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2 October 2017

A null mutation in the gene encoding a type I interferon receptor component eliminates antiproliferative and antiviral responses to interferons alpha and beta and alters macrophage responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4541718

2 October 2017

IL-28A (IFN-λ2) modulates lung DC function to promote Th1 immune skewing and suppress allergic airway disease

1 reference

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11 July 2018

Rhinovirus-induced interferon production is not deficient in well controlled asthma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4541718

24 September 2018

Dupilumab in persistent asthma with elevated eosinophil levels

1 reference

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24 September 2018

TLR7 stimulation of APCs results in inhibition of IL-5 through type I IFN and Notch signaling pathways in human peripheral blood mononuclear cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4541718

24 September 2018

Mepolizumab for severe eosinophilic asthma (DREAM): a multicentre, double-blind, placebo-controlled trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4541718

24 September 2018

Rhinovirus 16-induced IFN-α and IFN-β are deficient in bronchoalveolar lavage cells in asthmatic patients.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4541718

24 September 2018

Innate IFNs and plasmacytoid dendritic cells constrain Th2 cytokine responses to rhinovirus: a regulatory mechanism with relevance to asthma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4541718

24 September 2018

Double-stranded RNA induces disproportionate expression of thymic stromal lymphopoietin versus interferon-beta in bronchial epithelial cells from donors with asthma

1 reference

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24 September 2018

Pulmonary suppressor of cytokine signaling-1 induced by IL-13 regulates allergic asthma phenotype.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4541718

24 September 2018

Transforming growth factor-beta enhances rhinovirus infection by diminishing early innate responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4541718

24 September 2018

Severe exacerbations and decline in lung function in asthma

1 reference

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24 September 2018

The role of a soluble TNFalpha receptor fusion protein (etanercept) in corticosteroid refractory asthma: a double blind, randomised, placebo controlled trial.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4541718

24 September 2018

IL-4 suppresses dendritic cell response to type I interferons.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4541718

24 September 2018

Impaired virus-induced interferon-alpha2 release in adult asthmatic patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4541718

24 September 2018

Suppressor of cytokine signaling 1 regulates the immune response to infection by a unique inhibition of type I interferon activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4541718

24 September 2018

The September epidemic of asthma exacerbations in children: a search for etiology

1 reference

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24 September 2018

Interferon-gamma inhibits STAT6 signal transduction and gene expression in human airway epithelial cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4541718

24 September 2018

SOCS-3 regulates onset and maintenance of T(H)2-mediated allergic responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4541718

24 September 2018

Frequency, severity, and duration of rhinovirus infections in asthmatic and non-asthmatic individuals: a longitudinal cohort study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4541718

24 September 2018

Deficient antiviral immune responses in childhood: Distinct roles of atopy and asthma

1 reference

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14 November 2018

Peripheral Blood Mononuclear Cells from Patients with Bronchial Asthma Show Impaired Innate Immune Responses to Rhinovirus in vitro

1 reference

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14 November 2018

Functional Polymorphism in theSuppressor of Cytokine Signaling 1Gene Associated with Adult Asthma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4541718

14 November 2018

Role of deficient type III interferon-λ production in asthma exacerbations

1 reference

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14 November 2018

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10.1016/J.JACI.2014.11.039

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28 February 2020

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28 February 2020

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28 February 2020

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