Suppressor of cytokine signaling 1 regulates the immune response to infection by a unique inhibition of type I interferon activity (Q45345628)

13 December 2017

Suppressor of cytokine signaling 1 regulates the immune response to infection by a unique inhibition of type I interferon activity (English)

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13 December 2017

10

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13 December 2017

Douglas J Hilton

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Donald Metcalf

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object named as

Donald Metcalf

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13 December 2017

1

Jennifer E Fenner

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13 December 2017

2

Robyn Starr

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13 December 2017

Ann L Cornish

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13 December 2017

Jian-Guo Zhang

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13 December 2017

Robert D Schreiber

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13 December 2017

Kathleen Sheehan

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13 December 2017

Warren S Alexander

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13 December 2017

language of work or name

English

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publication date

27 November 2005

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13 December 2017

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13 December 2017

7

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1

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13 December 2017

33-39

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https://scigraph.springernature.com/pub.10.1038/ni1287

13 December 2017

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cites work

Cytokine therapeutics: lessons from interferon alpha

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Virus interference. I. The interferon

21 January 2018

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Interferons and their actions

21 January 2018

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Type I interferons and limitin: a comparison of structures, receptors, and functions

21 January 2018

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Type i interferons potently enhance humoral immunity and can promote isotype switching by stimulating dendritic cells in vivo.

21 January 2018

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The IFN gamma receptor: a paradigm for cytokine receptor signaling

21 January 2018

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NKT cells: facts, functions and fallacies.

21 January 2018

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Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins

21 January 2018

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How cells respond to interferons

21 January 2018

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How does interferon inhibit tumour growth?

21 January 2018

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Role of phosphatases in lymphocyte activation.

21 January 2018

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CD45 is a JAK phosphatase and negatively regulates cytokine receptor signalling

21 January 2018

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A family of cytokine-inducible inhibitors of signalling

21 January 2018

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A new protein containing an SH2 domain that inhibits JAK kinases

21 January 2018

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Structure and function of a new STAT-induced STAT inhibitor

21 January 2018

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Twenty proteins containing a C-terminal SOCS box form five structural classes

21 January 2018

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Mutational analyses of the SOCS proteins suggest a dual domain requirement but distinct mechanisms for inhibition of LIF and IL-6 signal transduction

21 January 2018

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Cytokine-inducible SH2 protein-3 (CIS3/SOCS3) inhibits Janus tyrosine kinase by binding through the N-terminal kinase inhibitory region as well as SH2 domain

21 January 2018

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The conserved SOCS box motif in suppressors of cytokine signaling binds to elongins B and C and may couple bound proteins to proteasomal degradation

21 January 2018

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Suppressor of cytokine signaling-3 preferentially binds to the SHP-2-binding site on the shared cytokine receptor subunit gp130

21 January 2018

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The JAK-binding protein JAB inhibits Janus tyrosine kinase activity through binding in the activation loop

21 January 2018

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The SOCS box: a tale of destruction and degradation

21 January 2018

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Growth hormone preferentially induces the rapid, transient expression of SOCS-3, a novel inhibitor of cytokine receptor signaling

21 January 2018

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Identification of SOCS-3 as a potential mediator of central leptin resistance

21 January 2018

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Liver degeneration and lymphoid deficiencies in mice lacking suppressor of cytokine signaling-1.

21 January 2018

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Accelerated apoptosis of lymphocytes by augmented induction of Bax in SSI-1 (STAT-induced STAT inhibitor-1) deficient mice

21 January 2018

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SOCS1 is a critical inhibitor of interferon gamma signaling and prevents the potentially fatal neonatal actions of this cytokine.

21 January 2018

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SOCS1 deficiency causes a lymphocyte-dependent perinatal lethality

21 January 2018

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The suppressor of cytokine signaling (SOCS) 1 and SOCS3 but not SOCS2 proteins inhibit interferon-mediated antiviral and antiproliferative activities

21 January 2018

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Suppressors of cytokine signaling and immunity

21 January 2018

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The lethal effects of transplantation of Socs1-/- bone marrow cells into irradiated adult syngeneic recipients

21 January 2018

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Multiple defects of immune cell function in mice with disrupted interferon-gamma genes

21 January 2018

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Cytokines in the generation of immune responses to, and resolution of, virus infection

21 January 2018

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Functional role of type I and type II interferons in antiviral defense

21 January 2018

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A null mutation in the gene encoding a type I interferon receptor component eliminates antiproliferative and antiviral responses to interferons alpha and beta and alters macrophage responses

21 January 2018

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The interferon in TLR signaling: more than just antiviral

21 January 2018

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Suppressor of cytokine signaling-1 is a critical regulator of interleukin-7-dependent CD8+ T cell differentiation.

21 January 2018

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A novel pathway regulating lipopolysaccharide-induced shock by ST2/T1 via inhibition of Toll-like receptor 4 expression

21 January 2018

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A critical function for type I interferons in cancer immunoediting

21 January 2018

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Proapoptotic BH3-only proteins trigger membrane integration of prosurvival Bcl-w and neutralize its activity

21 January 2018

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21 January 2018

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7 January 2021

Suppressor of Cytokine Signaling-1 Attenuates the Duration of Interferon γ Signal Transductionin Vitroandin Vivo

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7 January 2021

Interferons in rheumatoid arthritis: alterations in production and response related to disease activity

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7 January 2021

Neutralization of interferon-gamma in neonatal SOCS1-/- mice prevents fatty degeneration of the liver but not subsequent fatal inflammatory disease

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7 January 2021

Negative Regulation of Interleukin-12 Signaling by Suppressor of Cytokine Signaling-1

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7 January 2021

Cross talk between interferon-gamma and -alpha/beta signaling components in caveolar membrane domains

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7 January 2021

Suppressor of Cytokine Signaling-1 Regulates Signaling in Response to Interleukin-2 and Other γc-dependent Cytokines in Peripheral T Cells

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7 January 2021

Identifiers

DOI

10.1038/NI1287

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Dimensions Publication ID

13 December 2017

1015028067

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Fatcat ID

release_tqotha6wonew3c6jnsnphn4ryi

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Fatcat

https://api.fatcat.wiki/v0/release/tqotha6wonew3c6jnsnphn4ryi

24 November 2022

mapped directly with Wikidata item

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