Dependence of Wilms tumor cells on signaling through insulin-like growth factor 1 in an orthotopic xenograft model targetable by specific receptor inhibition. (Q35974177)

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English	Dependence of Wilms tumor cells on signaling through insulin-like growth factor 1 in an orthotopic xenograft model targetable by specific receptor inhibition.	scientific article

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29 January 2020

Dependence of Wilms tumor cells on signaling through insulin-like growth factor 1 in an orthotopic xenograft model targetable by specific receptor inhibition (English)

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29 January 2020

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29 January 2020

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29 January 2020

Florence Raynaud

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29 January 2020

Simon P Robinson

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29 January 2020

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29 January 2020

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Aleksandra Bielen

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29 January 2020

Gary Box

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29 January 2020

Lara Perryman

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29 January 2020

Lynn Bjerke

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29 January 2020

Sergey Popov

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29 January 2020

Alexa Jury

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29 January 2020

Melanie Valenti

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29 January 2020

Alexis de Haven Brandon

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29 January 2020

Vanessa Martins

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29 January 2020

Vincent Romanet

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29 January 2020

Francesco Hofmann

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29 January 2020

Suzanne A Eccles

16

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29 January 2020

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23 April 2012

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29 January 2020

Proceedings of the National Academy of Sciences of the United States of America

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29 January 2020

109

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29 January 2020

20

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29 January 2020

E1267-76

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29 January 2020

Initial testing (stage 1) of the IGF-1 receptor inhibitor BMS-754807 by the pediatric preclinical testing program.

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2 October 2017

Wt1 ablation and Igf2 upregulation in mice result in Wilms tumors with elevated ERK1/2 phosphorylation

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2 October 2017

Finding the tumor copycat: Approximating a human cancer

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2 October 2017

Tumour-microenvironmental interactions: paths to progression and targets for treatment

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2 October 2017

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2 October 2017

Initial testing of a monoclonal antibody (IMC-A12) against IGF-1R by the Pediatric Preclinical Testing Program.

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2 October 2017

Wilms tumor cells with WT1 mutations have characteristic features of mesenchymal stem cells and express molecular markers of paraxial mesoderm

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2 October 2017

Characterization of a WiT49 cell line derived orthotopic model of Wilms tumor

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2 October 2017

Molecular and phenotypic characterisation of paediatric glioma cell lines as models for preclinical drug development

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2 October 2017

The type 1 insulin-like growth factor receptor pathway

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2 October 2017

The type I insulin-like growth factor receptor pathway: a key player in cancer therapeutic resistance

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2 October 2017

A pathologic link between Wilms tumor suppressor gene, WT1, and IFI16.

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2 October 2017

Alternately spliced WT1 antisense transcripts interact with WT1 sense RNA and show epigenetic and splicing defects in cancer

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2 October 2017

Epigenetic specificity of loss of imprinting of the IGF2 gene in Wilms tumors.

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2 October 2017

Topotecan is active against Wilms' tumor: results of a multi-institutional phase II study

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2 October 2017

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2 October 2017

Disrupting insulin-like growth factor signaling as a potential cancer therapy

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2 October 2017

SK-NEP-1 and Rh1 are Ewing family tumor lines

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2 October 2017

Management of Wilms' tumour: current practice and future goals

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2 October 2017

Human tumor xenografts as predictive preclinical models for anticancer drug activity in humans: better than commonly perceived-but they can be improved

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2 October 2017

Derivation and characterization of a Wilms' tumour cell line, WiT 49.

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2 October 2017

Genetic changes of two Wilms tumors with anaplasia and a review of the literature suggesting a marker profile for therapy resistance

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2 October 2017

The G401 cell line, utilized for studies of chromosomal changes in Wilms' tumor, is derived from a rhabdoid tumor of the kidney.

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2 October 2017

Distinctive properties of an anaplastic Wilms' tumor and its associated epithelial cell line

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Blastemal expression of type I insulin-like growth factor receptor in Wilms' tumors is driven by increased copy number and correlates with relapse.

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Finding the tumor copycat: Therapy fails, patients don't

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Array CGH profiling of favourable histology Wilms tumours reveals novel gains and losses associated with relapse

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10.1073/PNAS.1105034109

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29 January 2020

2012PNAS..109E1267B

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29 January 2020

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29 January 2020

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