A Potent Systemically Active N-Acylethanolamine Acid Amidase Inhibitor that Suppresses Inflammation and Human Macrophage Activation. (Q35987617)

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5 March 2020

title

A Potent Systemically Active N-Acylethanolamine Acid Amidase Inhibitor that Suppresses Inflammation and Human Macrophage Activation (English)

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5 March 2020

4

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5 March 2020

Valerio Chiurchiù

5

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5 March 2020

Marco Mor

14

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5 March 2020

author name string

Alison Ribeiro

1

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5 March 2020

Silvia Pontis

2

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5 March 2020

Luisa Mengatto

3

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5 March 2020

Valeria Capurro

6

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5 March 2020

Annalisa Fiasella

7

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5 March 2020

Andrea Nuzzi

8

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5 March 2020

Elisa Romeo

9

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5 March 2020

Guillermo Moreno-Sanz

10

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5 March 2020

Mauro Maccarrone

11

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5 March 2020

Angelo Reggiani

12

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5 March 2020

Giorgio Tarzia

13

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5 March 2020

Fabio Bertozzi

15

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5 March 2020

Tiziano Bandiera

16

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5 March 2020

Daniele Piomelli

17

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publication date

15 April 2015

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5 March 2020

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5 March 2020

volume

10

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issue

8

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5 March 2020

page(s)

1838-1846

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β-Lactones Inhibit N-acylethanolamine Acid Amidase by S-Acylation of the Catalytic N-Terminal Cysteine

5 March 2020

cites work

1 reference

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2 October 2017

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Antinociceptive effects of the N-acylethanolamine acid amidase inhibitor ARN077 in rodent pain models

2 October 2017

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Peroxisome proliferator-activated receptor α mediates acute effects of palmitoylethanolamide on sensory neurons

2 October 2017

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Design and synthesis of potent N-acylethanolamine-hydrolyzing acid amidase (NAAA) inhibitor as anti-inflammatory compounds

2 October 2017

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Selective N-acylethanolamine-hydrolyzing acid amidase inhibition reveals a key role for endogenous palmitoylethanolamide in inflammation.

2 October 2017

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Lipidomic analysis of endocannabinoid metabolism in biological samples.

2 October 2017

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Molecular characterization of N-acylethanolamine-hydrolyzing acid amidase, a novel member of the choloylglycine hydrolase family with structural and functional similarity to acid ceramidase

2 October 2017

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The nuclear receptor peroxisome proliferator-activated receptor-alpha mediates the anti-inflammatory actions of palmitoylethanolamide.

2 October 2017

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N-cyclohexanecarbonylpentadecylamine: a selective inhibitor of the acid amidase hydrolysing N-acylethanolamines, as a tool to distinguish acid amidase from fatty acid amide hydrolase

2 October 2017

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Oleylethanolamide regulates feeding and body weight through activation of the nuclear receptor PPAR-alpha

2 October 2017

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2 October 2017

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3-Aminoazetidin-2-one derivatives as N-acylethanolamine acid amidase (NAAA) inhibitors suitable for systemic administration

27 July 2018

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Synthesis and structure-activity relationship (SAR) of 2-methyl-4-oxo-3-oxetanylcarbamic acid esters, a class of potent N-acylethanolamine acid amidase (NAAA) inhibitors

24 September 2018

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24 September 2018

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Purification and characterization of an acid amidase selective for N-palmitoylethanolamine, a putative endogenous anti-inflammatory substance

24 September 2018

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24 September 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/25874594

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Acute Intracerebroventricular Administration of Palmitoylethanolamide, an Endogenous Peroxisome Proliferator-Activated Receptor- Agonist, Modulates Carrageenan-Induced Paw Edema in Mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25874594

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Diacerein is a potent and selective inhibitor of palmitoylethanolamide inactivation with analgesic activity in a rat model of acute inflammatory pain

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25874594

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1021/ACSCHEMBIO.5B00114

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5 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25874594%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

1 reference

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