Insulin analogs for the treatment of diabetes mellitus: therapeutic applications of protein engineering. (Q35988978)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22641195%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

title

Insulin analogs for the treatment of diabetes mellitus: therapeutic applications of protein engineering (English)

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2 February 2020

1

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2 February 2020

author name string

Allison R Weiss

series ordinal

2

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2 February 2020

Zhu-Li Wan

series ordinal

3

1 reference

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2 February 2020

Michael A Weiss

series ordinal

4

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2 February 2020

language of work or name

English

0 references

publication date

1 December 2011

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Annals of the New York Academy of Sciences

2 February 2020

published in

1 reference

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2 February 2020

volume

1243

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2 February 2020

page(s)

E40-E54

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Conformational dynamics of insulin

2 February 2020

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2 October 2017

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2 October 2017

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Optimal control of blood glucose: the diabetic patient or the machine?

2 October 2017

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Supramolecular Protein Engineering: DESIGN OF ZINC-STAPLED INSULIN HEXAMERS AS A LONG ACTING DEPOT

2 October 2017

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Rapid-acting insulin analogues in Basal-bolus regimens in type 1 diabetes mellitus.

2 October 2017

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An Achilles' heel in an amyloidogenic protein and its repair: insulin fibrillation and therapeutic design

2 October 2017

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Virus assembly occurs following a pH- or Ca2+-triggered switch in the thermodynamic attraction between structural protein capsomeres.

2 October 2017

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Insulin glulisine: an evaluation of its pharmacodynamic properties and clinical application

2 October 2017

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Cost-effectiveness of insulin analogues for diabetes mellitus

2 October 2017

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Insulin analog therapy: improving the match with physiologic insulin secretion

2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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Intensive Diabetes Treatment and Cardiovascular Disease in Patients with Type 1 Diabetes

2 October 2017

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2 October 2017

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2 October 2017

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Are analogue insulins better than soluble in continuous subcutaneous insulin infusion? Results of a meta-analysis

2 October 2017

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2 October 2017

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Pathogenesis of type 1 and type 2 diabetes mellitus in sub-Saharan Africa: implications for transitional populations

2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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Glycosylated Insulin Complexed to Concanavalin A: Biochemical Basis for a Closed-Loop Insulin Delivery System

2 October 2017

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Atomic Positions in Rhombohedral 2-Zinc Insulin Crystals

2 October 2017

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Proposed structure for the zinc-binding domains from transcription factor IIIA and related proteins

2 October 2017

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The structure of 2Zn pig insulin crystals at 1.5 A resolution

2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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Receptor binding redefined by a structural switch in a mutant human insulin

2 October 2017

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Insulin hexamers: new conformations and applications

2 October 2017

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Altering the association properties of insulin by amino acid replacement

2 October 2017

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Structure of insulin in 4-zinc insulin

2 October 2017

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Chemical synthesis of [des(tetrapeptide B27--30), Tyr(NH2)26-B] and [des(pentapeptide B26--30), Phe(NH2)25-B] bovine insulins

2 October 2017

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Insulin degludec, an ultra-long-acting basal insulin, once a day or three times a week versus insulin glargine once a day in patients with type 2 diabetes: a 16-week, randomised, open-label, phase 2 trial

2 October 2017

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Effects of intensive glucose lowering in the management of patients with type 2 diabetes mellitus in the Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial

27 July 2018

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Intra-individual variability of the metabolic effect of a novel rapid-acting insulin (VIAject) in comparison to regular human insulin

27 July 2018

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27 July 2018

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Characterization of the R-state insulin hexamer and its derivatives. The hexamer is stabilized by heterotropic ligand binding interactions

27 July 2018

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The relationship between the exposure time of insulin glargine and risk of breast and prostate cancer: an observational study of the time-dependent effects of antidiabetic treatments in patients with diabetes.

27 July 2018

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U-100, pH-Neutral formulation of VIAject(®) : faster onset of action than insulin lispro in patients with type 1 diabetes.

24 September 2018

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Insulin glargine and NPH insulin increase to a similar degree epithelial cell proliferation and aberrant crypt foci formation in colons of diabetic mice

24 September 2018

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Intradermal microneedle delivery of insulin lispro achieves faster insulin absorption and insulin action than subcutaneous injection.

24 September 2018

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Diabetes treatment with insulin glargine and risk of malignancy: methodological pitfalls and ethical issues

24 September 2018

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Effect of a local heating device on insulin and glucose pharmacokinetic profiles in an open-label, randomized, two-period, one-way crossover study in patients with type 1 diabetes using continuous subcutaneous insulin infusion.

24 September 2018

1 reference

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Crystallographic and solution studies of N-lithocholyl insulin: a new generation of prolonged-acting human insulins

24 September 2018

1 reference

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Global epidemic of type 2 diabetes: implications for developing countries.

24 September 2018

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Structure of Rhombohedral 2 Zinc Insulin Crystals

24 September 2018

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Metallo-supramolecular modules as a paradigm for materials science

21 January 2018

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Structure of the alpha beta tubulin dimer by electron crystallography

21 January 2018

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The Mechanism of Protraction of Insulin Detemir, a Long-Acting, Acylated Analog of Human Insulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2012.06468.X

Phenol stabilizes more helix in a new symmetrical zinc insulin hexamer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2012.06468.X

Transmission of conformational change in insulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2012.06468.X

Insulin analogues and cancer risk: the emergence of second-generation studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2012.06468.X

Time-action profile of the long-acting insulin analog insulin glargine (HOE901) in comparison with those of NPH insulin and placebo

21 January 2018

1 reference

12 December 2020

Implications of the United Kingdom Prospective Diabetes Study (UKPDS) results on patient management

1 reference

12 December 2020

The global challenge of diabetes

1 reference

12 December 2020

1 reference

12 December 2020

UV cross-linked dextran methacrylate--concanavalin A methacrylamide gel materials for self-regulated insulin delivery

1 reference

12 December 2020

Insulin Glargine: a review 8 years after its introduction

1 reference

12 December 2020

Soluble, prolonged-acting insulin derivatives. III. Degree of protraction, crystallizability and chemical stability of insulins substituted in positions A21, B13, B23, B27 and B30

1 reference

12 December 2020

A shortened insulin with full in vitro potency

1 reference

12 December 2020

A glucose-controlled insulin-delivery system: semisynthetic insulin bound to lectin

1 reference

12 December 2020

Action profile of the rapid acting insulin analogue: human insulin B28Asp

1 reference

12 December 2020

Structure and dynamics of a protein assembly. 1H-NMR studies of the 36 kDa R6 insulin hexamer

1 reference

12 December 2020

Self-association properties of monomeric insulin analogs under formulation conditions

1 reference

12 December 2020

10.1111/J.1749-6632.2012.06468.X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22641195%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22641195%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22641195%20AND%20SRC:MED&resulttype=core&format=json