Mitochondrial failures in Alzheimer's disease (Q36000745)

11 August 2017

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title

Mitochondrial failures in Alzheimer's disease (English)

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11 August 2017

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3

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11 August 2017

1

Xiongwei Zhu

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11 August 2017

2

Mark A Smith

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11 August 2017

Gjumrakch Aliev

4

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PubMed ID

15633943

11 August 2017

language of work or name

English

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publication date

1 November 2004

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American Journal of Alzheimer's Disease & Other Dementias

11 August 2017

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11 August 2017

19

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11 August 2017

6

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11 August 2017

345-352

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Mitochondrial free radical generation, oxidative stress, and aging

11 August 2017

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https://api.crossref.org/works/10.1177%2F153331750401900611

Role of mitochondrial dysfunction in Alzheimer's disease

21 January 2018

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https://api.crossref.org/works/10.1177%2F153331750401900611

Abnormalities of mitochondrial enzymes in Alzheimer disease.

21 January 2018

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https://api.crossref.org/works/10.1177%2F153331750401900611

Impairment in mitochondrial cytochrome oxidase gene expression in Alzheimer disease.

21 January 2018

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https://api.crossref.org/works/10.1177%2F153331750401900611

Mitochondrial enzyme-deficient hippocampal neurons and choroidal cells in AD.

21 January 2018

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https://api.crossref.org/works/10.1177%2F153331750401900611

A selective defect of cytochrome c oxidase is present in brain of Alzheimer disease patients.

21 January 2018

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https://api.crossref.org/works/10.1177%2F153331750401900611

Mitochondrial enzyme expression in the hippocampus in relation to Alzheimer-type pathology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153331750401900611

Reduced platelet cytochrome c oxidase activity in Alzheimer's disease.

21 January 2018

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https://api.crossref.org/works/10.1177%2F153331750401900611

Electron transport chain defects in Alzheimer's disease brain.

21 January 2018

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https://api.crossref.org/works/10.1177%2F153331750401900611

Mutations in mitochondrial cytochrome c oxidase genes segregate with late-onset Alzheimer disease

21 January 2018

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https://api.crossref.org/works/10.1177%2F153331750401900611

Cybrids in Alzheimer's disease: a cellular model of the disease?

21 January 2018

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https://api.crossref.org/works/10.1177%2F153331750401900611

Oxidative damage to mitochondrial DNA shows marked age-dependent increases in human brain.

21 January 2018

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https://api.crossref.org/works/10.1177%2F153331750401900611

Mitochondrial membrane fluidity and oxidative damage to mitochondrial DNA in aged and AD human brain.

21 January 2018

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https://api.crossref.org/works/10.1177%2F153331750401900611

Oxidative damage to DNA in lymphocytes from AD patients.

21 January 2018

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https://api.crossref.org/works/10.1177%2F153331750401900611

Alzheimer's brains harbor somatic mtDNA control-region mutations that suppress mitochondrial transcription and replication

21 January 2018

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https://api.crossref.org/works/10.1177%2F153331750401900611

Mitochondrial alterations in Alzheimer's disease.

21 January 2018

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https://api.crossref.org/works/10.1177%2F153331750401900611

Metabolic reduction in the posterior cingulate cortex in very early Alzheimer's disease.

21 January 2018

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https://api.crossref.org/works/10.1177%2F153331750401900611

Intermediary metabolism disturbance in AD/SDAT and its relation to molecular events.

21 January 2018

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https://api.crossref.org/works/10.1177%2F153331750401900611

Cerebrometabolic aspects of delirium in relationship to dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153331750401900611

Oxidative stress, glutamate, and neurodegenerative disorders

21 January 2018

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https://api.crossref.org/works/10.1177%2F153331750401900611

Oxidative stress signalling in Alzheimer's disease

21 January 2018

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https://api.crossref.org/works/10.1177%2F153331750401900611

Parkinson's disease is associated with oxidative stress: comparison of peripheral antioxidant profiles in living Parkinson's, Alzheimer's and vascular dementia patients

21 January 2018

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https://api.crossref.org/works/10.1177%2F153331750401900611

Cerebrovascular hypoperfusion: a risk factor for Alzheimer's disease? Animal model and postmortem human studies

21 January 2018

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https://api.crossref.org/works/10.1177%2F153331750401900611

Cerebromicrovascular pathology in Alzheimer's disease compared to normal aging

21 January 2018

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https://api.crossref.org/works/10.1177%2F153331750401900611

Alzheimer disease as a vascular disorder: nosological evidence

21 January 2018

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https://api.crossref.org/works/10.1177%2F153331750401900611

Critically attained threshold of cerebral hypoperfusion: the CATCH hypothesis of Alzheimer's pathogenesis

21 January 2018

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https://api.crossref.org/works/10.1177%2F153331750401900611

Mitochondrial targeting and a novel transmembrane arrest of Alzheimer's amyloid precursor protein impairs mitochondrial function in neuronal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153331750401900611

Transfer of beta-amyloid precursor protein gene using adenovirus vector causes mitochondrial abnormalities in cultured normal human muscle

21 January 2018

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https://api.crossref.org/works/10.1177%2F153331750401900611

Beta-amyloid inhibits integrated mitochondrial respiration and key enzyme activities

21 January 2018

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https://api.crossref.org/works/10.1177%2F153331750401900611

Effect of amyloid beta-peptide on permeability transition pore: a comparative study.

21 January 2018

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https://api.crossref.org/works/10.1177%2F153331750401900611

The alpha-ketoglutarate dehydrogenase complex in neurodegeneration

21 January 2018

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https://api.crossref.org/works/10.1177%2F153331750401900611

Brain energy metabolizing enzymes in Alzheimer's disease: alpha-ketoglutarate dehydrogenase complex and cytochrome oxidase

21 January 2018

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https://api.crossref.org/works/10.1177%2F153331750401900611

ABAD directly links Abeta to mitochondrial toxicity in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153331750401900611

Atherosclerotic lesions and mitochondria DNA deletions in brain microvessels as a central target for the development of human AD and AD-like pathology in aged transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153331750401900611

Mitochondria and degenerative disorders

21 January 2018

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https://api.crossref.org/works/10.1177%2F153331750401900611

Mitochondrial DNA mutations and pathogenesis

21 January 2018

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https://api.crossref.org/works/10.1177%2F153331750401900611

A mitochondrial DNA clone is associated with increased risk for Alzheimer disease

21 January 2018

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https://api.crossref.org/works/10.1177%2F153331750401900611

Mitochondrial DNA variants observed in Alzheimer disease and Parkinson disease patients.

21 January 2018

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https://api.crossref.org/works/10.1177%2F153331750401900611

No association found between Alzheimer's disease and a mitochondrial tRNA glutamine gene variant.

21 January 2018

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https://api.crossref.org/works/10.1177%2F153331750401900611

Mitochondrial dysfunction and Down's syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153331750401900611

Brain hydrogen sulfide is severely decreased in Alzheimer's disease

21 January 2018

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https://api.crossref.org/works/10.1177%2F153331750401900611

Plasma homocysteine as a risk factor for dementia and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153331750401900611

Homocysteine-dependent alterations in mitochondrial gene expression, function and structure. Homocysteine and H2O2 act synergistically to enhance mitochondrial damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153331750401900611

In vitro effect of homocysteine on some parameters of oxidative stress in rat hippocampus

21 January 2018

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https://api.crossref.org/works/10.1177%2F153331750401900611

Brain energy metabolism is compromised by the metabolites accumulating in homocystinuria

21 January 2018

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https://api.crossref.org/works/10.1177%2F153331750401900611

Impairment of energy metabolism in hippocampus of rats subjected to chemically-induced hyperhomocysteinemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153331750401900611

Effects of taurine and homocysteine on calcium homeostasis and hydrogen peroxide and superoxide anions in rat myocardial mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153331750401900611

Altered gene expression in liver from a murine model of hyperhomocysteinemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153331750401900611

Oxidative damage is the earliest event in Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153331750401900611

Oxidative damage to mitochondrial DNA is increased in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153331750401900611

10.1177/153331750401900611

21 January 2018

Identifiers

DOI

1 reference

11 August 2017

1 reference

PubMed ID

15633943