CD8+ T cells directed against a viral peptide contribute to loss of motor function by disrupting axonal transport in a viral model of fulminant demyelination (Q36003488)

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English	CD8+ T cells directed against a viral peptide contribute to loss of motor function by disrupting axonal transport in a viral model of fulminant demyelination	scientific article

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scholarly article

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Europe PubMed Central

PMC publication ID

11 August 2017

CD8+ T cells directed against a viral peptide contribute to loss of motor function by disrupting axonal transport in a viral model of fulminant demyelination (English)

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

author name string

Charles L Howe

1

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Daren Ure

2

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Jaimie D Adelson

3

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Reghann LaFrance-Corey

4

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Aaron Johnson

5

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Moses Rodriguez

6

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

publication date

9 May 2007

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Europe PubMed Central

PMC publication ID

11 August 2017

Journal of Neuroimmunology

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Europe PubMed Central

PMC publication ID

11 August 2017

188

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Europe PubMed Central

PMC publication ID

11 August 2017

1-2

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

13-21

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Antigen presentation in the CNS by myeloid dendritic cells drives progression of relapsing experimental autoimmune encephalomyelitis

1 reference

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2 October 2017

Axonal conduction and injury in multiple sclerosis: the role of sodium channels

1 reference

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2 October 2017

Absence of perforin expression confers axonal protection despite demyelination.

1 reference

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2 October 2017

Mechanisms of immunopathology in murine models of central nervous system demyelinating disease

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Picornaviruses and cell death.

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Minocycline attenuates T cell and microglia activity to impair cytokine production in T cell-microglia interaction

1 reference

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Trophic factors attenuate nitric oxide mediated neuronal and axonal injury in vitro: roles and interactions of mitogen-activated protein kinase signalling pathways.

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Microglia initiate central nervous system innate and adaptive immune responses through multiple TLRs

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Expression of major histocompatibility complex class I molecules on the different cell types in multiple sclerosis lesions.

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Gamma interferon is critical for neuronal viral clearance and protection in a susceptible mouse strain following early intracranial Theiler's murine encephalomyelitis virus infection.

1 reference

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Molecular mechanisms of axonal damage in inflammatory central nervous system diseases

1 reference

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Cytotoxic T lymphocytes in autoimmune and degenerative CNS diseases.

1 reference

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Cellular sources and targets of IFN-gamma-mediated protection against viral demyelination and neurological deficits.

1 reference

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Direct activation of innate and antigen-presenting functions of microglia following infection with Theiler's virus

1 reference

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Clonal expansions of CD8(+) T cells dominate the T cell infiltrate in active multiple sclerosis lesions as shown by micromanipulation and single cell polymerase chain reaction

1 reference

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Axonal loss results in spinal cord atrophy, electrophysiological abnormalities and neurological deficits following demyelination in a chronic inflammatory model of multiple sclerosis

1 reference

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Quantitation of spinal cord demyelination, remyelination, atrophy, and axonal loss in a model of progressive neurologic injury

1 reference

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Quantitative assessment of neurologic deficits in a chronic progressive murine model of CNS demyelination.

1 reference

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Absence of neurological deficits following extensive demyelination in a class I-deficient murine model of multiple sclerosis

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Indictment of the microglia as the villain in multiple sclerosis

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2 October 2017

Theiler's virus infection of 129Sv mice that lack the interferon alpha/beta or interferon gamma receptors

1 reference

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Immunoglobulins stimulate central nervous system remyelination: electron microscopic and morphometric analysis of proliferating cells

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Theiler's virus infection in mice: an unusual biphasic disease process leading to demyelination

1 reference

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Transection of major histocompatibility complex class I-induced neurites by cytotoxic T lymphocytes

1 reference

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Neonatal infection with the Daniels strain of Theiler's murine encephalomyelitis virus

1 reference

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Sodium channels contribute to microglia/macrophage activation and function in EAE and MS.

1 reference

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Clearance of Theiler's virus infection depends on the ability to generate a CD8+ T cell response against a single immunodominant viral peptide

1 reference

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MHC gene related effects on microglia and macrophages in experimental autoimmune encephalomyelitis determine the extent of axonal injury.

1 reference

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Preservation of motor function by inhibition of CD8+ virus peptide-specific T cells in Theiler's virus infection

1 reference

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CD8-deficient SJL mice display enhanced susceptibility to Theiler's virus infection and increased demyelinating pathology

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Transected neurites, apoptotic neurons, and reduced inflammation in cortical multiple sclerosis lesions.

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EAE in beta-2 microglobulin-deficient mice: axonal damage is not dependent on MHC-I restricted immune responses

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Identifiers

10.1016/J.JNEUROIM.2007.04.005

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

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