Duplex RNA-binding enzymes: headliners from neurobiology, virology, and development (Q36006780)

11 August 2017

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title

Duplex RNA-binding enzymes: headliners from neurobiology, virology, and development (English)

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11 August 2017

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Peter A Beal

1

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11 August 2017

1 February 2005

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11 August 2017

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11 August 2017

6

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11 August 2017

2

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11 August 2017

257-266

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A conserved double-stranded RNA-binding domain

11 August 2017

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

Proteins binding to duplexed RNA: one motif, multiple functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

New and old roles of the double-stranded RNA-binding domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

Structure of the double-stranded RNA-binding domain of the protein kinase PKR reveals the molecular basis of its dsRNA-mediated activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

Molecular basis of double-stranded RNA-protein interactions: structure of a dsRNA-binding domain complexed with dsRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

RNA recognition by a Staufen double-stranded RNA-binding domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

Selective binding by the RNA binding domain of PKR revealed by affinity cleavage

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

Identification of binding sites for both dsRBMs of PKR on kinase-activating and kinase-inhibiting RNA ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

The binding site of the RNA-dependent protein kinase (PKR) on EBER1 RNA from Epstein-Barr virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

The binding selectivity of ADAR2's dsRBMs contributes to RNA-editing selectivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

Biochemical analysis and scanning force microscopy reveal productive and nonproductive ADAR2 binding to RNA substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

Minor-groove recognition of double-stranded RNA by the double-stranded RNA-binding domain from the RNA-activated protein kinase PKR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

A dynamically tuned double-stranded RNA binding mechanism for the activation of antiviral kinase PKR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

Regulation of serotonin-2C receptor G-protein coupling by RNA editing

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

RNA editing of AMPA receptor subunit GluR-B: a base-paired intron-exon structure determines position and efficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

Nervous system targets of RNA editing identified by comparative genomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

Control of kinetic properties of AMPA receptor channels by nuclear RNA editing

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

Point mutation in an AMPA receptor gene rescues lethality in mice deficient in the RNA-editing enzyme ADAR2

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

Requirement of the RNA editing deaminase ADAR1 gene for embryonic erythropoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

A-to-I pre-mRNA editing in Drosophila is primarily involved in adult nervous system function and integrity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

RNA editing by ADARs is important for normal behavior in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

RNA editing of the human serotonin 5-HT2C receptor. alterations in suicide and implications for serotonergic pharmacotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

RNA editing of serotonin 2C receptor in human postmortem brains of major mental disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

Altered editing of serotonin 2C receptor pre-mRNA in the prefrontal cortex of depressed suicide victims

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

Altered RNA editing of serotonin 5-HT2C receptor induced by interferon: implications for depression associated with cytokine therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

Long RNA hairpins that contain inosine are present in Caenorhabditis elegans poly(A)+ RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

A mammalian RNA editing enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

Purification of human double-stranded RNA-specific editase 1 (hRED1) involved in editing of brain glutamate receptor B pre-mRNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

Crystal structure of the Zalpha domain of the human editing enzyme ADAR1 bound to left-handed Z-DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

Mutagenic analysis of double-stranded RNA adenosine deaminase, a candidate enzyme for RNA editing of glutamate-gated ion channel transcripts

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

The nucleoside deaminases for cytidine and adenosine: structure, transition state stabilization, mechanism, and evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

Tad1p, a yeast tRNA-specific adenosine deaminase, is related to the mammalian pre-mRNA editing enzymes ADAR1 and ADAR2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

The mechanism of adenosine to inosine conversion by the double-stranded RNA unwinding/modifying activity: a high-performance liquid chromatography-mass spectrometry analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

Substrate analogues for an RNA-editing adenosine deaminase: mechanistic investigation and inhibitor design

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

Analysis of the RNA-editing reaction of ADAR2 with structural and fluorescent analogues of the GluR-B R/G editing site.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

Evidence for auto-inhibition by the N terminus of hADAR2 and activation by dsRNA binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

An ADAR that edits transcripts encoding ion channel subunits functions as a dimer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

Adenosine to inosine editing by ADAR2 requires formation of a ternary complex on the GluR-B R/G site

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

Requirement of dimerization for RNA editing activity of adenosine deaminases acting on RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

A transition state analogue for an RNA-editing reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

Covalent trapping of protein-DNA complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

Structure and sequence determinants required for the RNA editing of ADAR2 substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

RNase III enzymes and the initiation of gene silencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

Precursors to 16S and 23S ribosomal RNA from a ribonuclease III−strain of Escherichia coli contain intact RNase III processing sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

Role for a bidentate ribonuclease in the initiation step of RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

The nuclear RNase III Drosha initiates microRNA processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

The crystal structure of the Argonaute2 PAZ domain reveals an RNA binding motif in RNAi effector complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

The microRNA world: small is mighty

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

The microRNA-producing enzyme Dicer1 is essential for zebrafish development

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

Dicer is essential for mouse development

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

bantam encodes a developmentally regulated microRNA that controls cell proliferation and regulates the proapoptotic gene hid in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

Crystallographic and modeling studies of RNase III suggest a mechanism for double-stranded RNA cleavage

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

Single processing center models for human Dicer and bacterial RNase III

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

Human Dicer preferentially cleaves dsRNAs at their termini without a requirement for ATP

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

A Dicer-2-dependent 80s complex cleaves targeted mRNAs during RNAi in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

Sequence-specific inhibition of small RNA function

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

Recognition of duplex RNA by helix-threading peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

Phosphorylation of initiation factor elF-2 and the control of reticulocyte protein synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

PKR; a sentinel kinase for cellular stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

eIF-2 kinases: regulators of general and gene-specific translation initiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

Molecular mechanisms of interferon resistance mediated by viral-directed inhibition of PKR, the interferon-induced protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

Interactions between double-stranded RNA regulators and the protein kinase DAI

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

Activation of the interferon system by short-interfering RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

Regulation of the interferon-inducible eIF-2 alpha protein kinase by small RNAs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

Proteins that interact with PKR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

Translational control by the Epstein-Barr virus small RNA EBER-1. Reversal of the double-stranded RNA-induced inhibition of protein synthesis in reticulocyte lysates

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

Malignant transformation by a mutant of the IFN-inducible dsRNA-dependent protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

Tumor suppressor function of the interferon-induced double-stranded RNA-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

In vitro activation of the interferon-induced, double-stranded RNA-dependent protein kinase PKR by RNA from the 3' untranslated regions of human alpha-tropomyosin

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

Expression of a PKR dominant-negative mutant in myogenic cells interferes with the myogenic process

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

The 58,000-dalton cellular inhibitor of the interferon-induced double-stranded RNA-activated protein kinase (PKR) is a member of the tetratricopeptide repeat family of proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

Double-stranded RNA-dependent protein kinase activates transcription factor NF-kappa B by phosphorylating I kappa B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

Deficient cytokine signaling in mouse embryo fibroblasts with a targeted deletion in the PKR gene: role of IRF-1 and NF-kappaB

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

Physical association between STAT1 and the interferon-inducible protein kinase PKR and implications for interferon and double-stranded RNA signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

Nuclear factor 90 is a substrate and regulator of the eukaryotic initiation factor 2 kinase double-stranded RNA-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

Molecular cloning and characterization of the human double-stranded RNA-activated protein kinase induced by interferon

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

Site-specific modification of Epstein-Barr virus-encoded RNA 1 with N2-benzylguanosine limits the binding sites occupied by PKR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

Functional characterization of and cooperation between the double-stranded RNA-binding motifs of the protein kinase PKR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

Characterization of the solution complex between the interferon-induced, double-stranded RNA-activated protein kinase and HIV-I trans-activating region RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

Double-stranded (ds) RNA binding and not dimerization correlates with the activation of the dsRNA-dependent protein kinase (PKR).

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

The regulation of the protein kinase PKR by RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

Heterologous dimerization domains functionally substitute for the double-stranded RNA binding domains of the kinase PKR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

Controlling protein association and subcellular localization with a synthetic ligand that induces heterodimerization of proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

Autophosphorylation sites participate in the activation of the double-stranded-RNA-activated protein kinase PKR

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

Identification of phosphorylation sites in proteins separated by polyacrylamide gel electrophoresis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

Phosphorylation of the RNA-dependent protein kinase regulates its RNA-binding activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

Specific interference with gene expression induced by long, double-stranded RNA in mouse embryonal teratocarcinoma cell lines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

Nonspecific, concentration-dependent stimulation and repression of mammalian gene expression by small interfering RNAs (siRNAs).

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

Short interfering RNAs can induce unexpected and divergent changes in the levels of untargeted proteins in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

Characterization of transgenic mice with targeted disruption of the catalytic domain of the double-stranded RNA-dependent protein kinase, PKR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

Functional characterization of pkr gene products expressed in cells from mice with a targeted deletion of the N terminus or C terminus domain of PKR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

Recent advances in chemical approaches to the study of biological systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

Adenovirus inhibition of cellular protein synthesis is prevented by the drug 2-aminopurine

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

Modulation of murine phenobarbital-inducible CYP2A5, CYP2B10 and CYP1A enzymes by inhibitors of protein kinases and phosphatases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

2-Aminopurine overrides multiple cell cycle checkpoints in BHK cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

Small molecule inhibitors of the RNA-dependent protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

Structural determinants of ion flow through recombinant glutamate receptor channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

Structural Requirements for RNA Editing in Glutamate Receptor Pre-mRNAs by Recombinant Double-stranded RNA Adenosine Deaminase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400303

21 January 2018

Identifiers

DOI

10.1002/CBIC.200400303

1 reference

11 August 2017

1 reference

PubMed ID

15645515