siRNA Design Software for a Target Gene-Specific RNA Interference. (Q36021477)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22701467%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

title

siRNA Design Software for a Target Gene-Specific RNA Interference (English)

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5 February 2020

0 references

0 references

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1

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5 February 2020

author name string

Kumiko Ui-Tei

series ordinal

2

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5 February 2020

publication date

11 June 2012

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5 February 2020

published in

Frontiers in Genetics

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5 February 2020

volume

3

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5 February 2020

page(s)

102

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5 February 2020

cites work

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2 October 2017

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siDirect 2.0: updated software for designing functional siRNA with reduced seed-dependent off-target effect

2 October 2017

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AsiDesigner: exon-based siRNA design server considering alternative splicing

2 October 2017

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MicroRNA targeting specificity in mammals: determinants beyond seed pairing

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2 October 2017

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More complete gene silencing by fewer siRNAs: transparent optimized design and biophysical signature

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An accurate and interpretable model for siRNA efficacy prediction

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3' UTR seed matches, but not overall identity, are associated with RNAi off-targets

2 October 2017

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Cleavage of the siRNA passenger strand during RISC assembly in human cells

2 October 2017

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Passenger-strand cleavage facilitates assembly of siRNA into Ago2-containing RNAi enzyme complexes

2 October 2017

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Argonaute2 cleaves the anti-guide strand of siRNA during RISC activation

2 October 2017

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Crystal structure of A. aeolicus argonaute, a site-specific DNA-guided endoribonuclease, provides insights into RISC-mediated mRNA cleavage

2 October 2017

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Structural basis for 5'-end-specific recognition of guide RNA by the A. fulgidus Piwi protein

2 October 2017

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Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs

2 October 2017

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Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets

2 October 2017

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siRNA Selection Server: an automated siRNA oligonucleotide prediction server

2 October 2017

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DEQOR: a web-based tool for the design and quality control of siRNAs

2 October 2017

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Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference

2 October 2017

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Rational siRNA design for RNA interference

2 October 2017

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Functional siRNAs and miRNAs Exhibit Strand Bias

2 October 2017

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Asymmetry in the assembly of the RNAi enzyme complex

2 October 2017

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Expression profiling reveals off-target gene regulation by RNAi

2 October 2017

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Single-stranded antisense siRNAs guide target RNA cleavage in RNAi

2 October 2017

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Analysis of gene function in somatic mammalian cells using small interfering RNAs

2 October 2017

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2 October 2017

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Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

2 October 2017

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Thermodynamic stability and Watson-Crick base pairing in the seed duplex are major determinants of the efficiency of the siRNA-based off-target effect.

2 October 2017

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Widespread siRNA "off-target" transcript silencing mediated by seed region sequence complementarity

11 July 2018

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siDRM: an effective and generally applicable online siRNA design tool.

11 July 2018

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OptiRNAi, an RNAi design tool.

23 September 2018

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An algorithm for selection of functional siRNA sequences.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3371628

23 September 2018

Identifiers

DOI

10.3389/FGENE.2012.00102

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22701467%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22701467%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22701467%20AND%20SRC:MED&resulttype=core&format=json