Wiring diagrams of MAPK regulation by MEKK1, 2, and 3. (Q36021528)

11 August 2017

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title

Wiring diagrams of MAPK regulation by MEKK1, 2, and 3. (English)

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11 August 2017

Mark T Uhlik

1

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11 August 2017

Amy N Abell

2

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11 August 2017

Bruce D Cuevas

3

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11 August 2017

Kazuhiro Nakamura

4

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11 August 2017

Gary L Johnson

5

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11 August 2017

language of work or name

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1 December 2004

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Biochemistry and Cell Biology

11 August 2017

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11 August 2017

82

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11 August 2017

6

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11 August 2017

658-663

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Role of MEKK2-MEK5 in the regulation of TNF-alpha gene expression and MEKK2-MKK7 in the activation of c-Jun N-terminal kinase in mast cells

11 August 2017

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MEKK1 regulates calpain-dependent proteolysis of focal adhesion proteins for rear-end detachment of migrating fibroblasts.

21 January 2018

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MEK kinases are regulated by EGF and selectively interact with Rac/Cdc42

21 January 2018

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RhoA binds to the amino terminus of MEKK1 and regulates its kinase activity

21 January 2018

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Organization and regulation of mitogen-activated protein kinase signaling pathways

21 January 2018

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MEKK2 gene disruption causes loss of cytokine production in response to IgE and c-Kit ligand stimulation of ES cell-derived mast cells

21 January 2018

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Disruption of Mekk2 in mice reveals an unexpected role for MEKK2 in modulating T-cell receptor signal transduction

21 January 2018

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From molecular to modular cell biology

21 January 2018

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Lethality and centrality in protein networks

21 January 2018

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MEKK2 regulates the coordinate activation of ERK5 and JNK in response to FGF-2 in fibroblasts.

21 January 2018

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Interaction codes within the family of mammalian Phox and Bem1p domain-containing proteins

21 January 2018

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Mutations in a gene encoding a novel protein containing a phosphotyrosine-binding domain cause type 2 cerebral cavernous malformations

21 January 2018

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PB1 domains of MEKK2 and MEKK3 interact with the MEK5 PB1 domain for activation of the ERK5 pathway

21 January 2018

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Molecular recognition in dimerization between PB1 domains

21 January 2018

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From large networks to small molecules

21 January 2018

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MEKK2 associates with the adapter protein Lad/RIBP and regulates the MEK5-BMK1/ERK5 pathway

21 January 2018

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Rac-MEKK3-MKK3 scaffolding for p38 MAPK activation during hyperosmotic shock.

21 January 2018

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Ubiquitylation of MEKK1 inhibits its phosphorylation of MKK1 and MKK4 and activation of the ERK1/2 and JNK pathways

21 January 2018

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MEKK1 is required for inducible urokinase-type plasminogen activator expression

21 January 2018

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Mekk3 is essential for early embryonic cardiovascular development

21 January 2018

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The essential role of MEKK3 in TNF-induced NF-kappaB activation

21 January 2018

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Role of MEKK1 in cell survival and activation of JNK and ERK pathways defined by targeted gene disruption

21 January 2018

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MEK kinase 1 gene disruption alters cell migration and c-Jun NH2-terminal kinase regulation but does not cause a measurable defect in NF-kappa B activation

21 January 2018

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21 January 2018

Identifiers

DOI

10.1139/O04-114

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11 August 2017

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