Parkinson's disease-linked LRRK2 is expressed in circulating and tissue immune cells and upregulated following recognition of microbial structures (Q36037105)

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English	Parkinson's disease-linked LRRK2 is expressed in circulating and tissue immune cells and upregulated following recognition of microbial structures	scientific article

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21552986%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

Parkinson's disease-linked LRRK2 is expressed in circulating and tissue immune cells and upregulated following recognition of microbial structures (English)

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31 January 2020

Parkinson's disease

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Thirumahal Selvanantham

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31 January 2020

13

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31 January 2020

Jonathan B Angel

14

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31 January 2020

Michael G Schlossmacher

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31 January 2020

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Mansoureh Hakimi

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31 January 2020

Erika Swinton

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31 January 2020

Ruth F Padmore

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31 January 2020

Youren Tong

5

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31 January 2020

Ghassan Kabbach

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31 January 2020

Katerina Venderova

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31 January 2020

Stephen E Girardin

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31 January 2020

Dennis E Bulman

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31 January 2020

Clemens R Scherzer

10

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31 January 2020

Matthew J LaVoie

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31 January 2020

Denis Gris

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31 January 2020

Jie Shen

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31 January 2020

Dana J Philpott

16

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31 January 2020

publication date

7 May 2011

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31 January 2020

Journal of Neural Transmission

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31 January 2020

118

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31 January 2020

5

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31 January 2020

795-808

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31 January 2020

Acid β-glucosidase mutants linked to Gaucher disease, Parkinson disease, and Lewy body dementia alter α-synuclein processing.

1 reference

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2 October 2017

Translational research in neurology and neuroscience 2011: movement disorders

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2 October 2017

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2 October 2017

The role of leucine-rich repeat kinase 2 (LRRK2) in Parkinson's disease

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2 October 2017

LRRK2 is involved in the IFN-gamma response and host response to pathogens

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2 October 2017

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2 October 2017

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2 October 2017

Membrane localization of LRRK2 is associated with increased formation of the highly active LRRK2 dimer and changes in its phosphorylation

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2 October 2017

Loss of leucine-rich repeat kinase 2 causes impairment of protein degradation pathways, accumulation of alpha-synuclein, and apoptotic cell death in aged mice

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Aspergillus fumigatus stimulates the NLRP3 inflammasome through a pathway requiring ROS production and the Syk tyrosine kinase.

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Leucine-rich repeat kinase 2 gene-associated disease: redefining genotype-phenotype correlation

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alpha-synuclein and LRRK2: partners in crime

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Genome-wide association study reveals genetic risk underlying Parkinson's disease

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2 October 2017

Leucine-Rich Repeat Kinase 2 interacts with Parkin, DJ-1 and PINK-1 in a Drosophila melanogaster model of Parkinson's disease

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2 October 2017

R1441C mutation in LRRK2 impairs dopaminergic neurotransmission in mice.

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2 October 2017

LRRK2 regulates autophagic activity and localizes to specific membrane microdomains in a novel human genomic reporter cellular model

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2 October 2017

Leucine-rich repeat kinase 2 mutations and Parkinson's disease: three questions

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2 October 2017

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2 October 2017

Neuroinflammation in Parkinson's disease: a target for neuroprotection?

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2 October 2017

Glucocerebrosidase mutations in clinical and pathologically proven Parkinson's disease

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2 October 2017

Update on the functional biology of Lrrk2.

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2 October 2017

Cathepsin D expression level affects alpha-synuclein processing, aggregation, and toxicity in vivo.

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2 October 2017

Infiltration of CD4+ lymphocytes into the brain contributes to neurodegeneration in a mouse model of Parkinson disease.

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Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

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2 October 2017

Dynamic and redundant regulation of LRRK2 and LRRK1 expression

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2 October 2017

Peripheral inflammatory biomarkers and risk of Parkinson's disease

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2 October 2017

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2 October 2017

Genetic predisposition to leprosy: A major gene reveals novel pathways of immunity to Mycobacterium leprae

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2 October 2017

LRRK2 in Parkinson's disease: protein domains and functional insights

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2 October 2017

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2 October 2017

Parkinson's disease-associated mutations in leucine-rich repeat kinase 2 augment kinase activity

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1 reference

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Age-dependent and cell-population-restricted LRRK2 expression in normal mouse spleen.

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The Parkinson disease gene LRRK2: evolutionary and structural insights

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

LRRK2 screening in a Canadian Parkinson's disease cohort

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https://pubmed.ncbi.nlm.nih.gov/21552986

12 December 2020

based on heuristic

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A common genetic fingerprint in leprosy and Crohn's disease?

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12 December 2020

based on heuristic

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31 January 2020

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31 January 2020

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