Rational protein design: combining theory and experiment (Q36037334)

11 August 2017

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title

Rational protein design: combining theory and experiment (English)

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11 August 2017

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H W Hellinga

1

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PMC publication ID

33767

11 August 2017

language of work or name

English

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publication date

1 September 1997

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Proceedings of the National Academy of Sciences of the United States of America

11 August 2017

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11 August 2017

94

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11 August 2017

19

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11 August 2017

10015-10017

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The dead-end elimination theorem and its use in protein side-chain positioning

11 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33767

Probing the role of packing specificity in protein design

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33767

Protein alchemy: changing beta-sheet into alpha-helix

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33767

De novo design of the hydrophobic core of ubiquitin

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33767

Construction of a catalytically active iron superoxide dismutase by rational protein design

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33767

Protein design: the choice of de novo sequences

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33767

2 October 2017

Metalloprotein design

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33767

Protein design automation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33767

Sequence space, folding and protein design

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33767

De novo design of the hydrophobic cores of proteins

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33767

Synthesis, structure and activity of artificial, rationally designed catalytic polypeptides

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33767

A switch between two-, three-, and four-stranded coiled coils in GCN4 leucine zipper mutants

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33767

Betadoublet: de novo design, synthesis, and characterization of a beta-sandwich protein

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33767

A test of lattice protein folding algorithms

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33767

Repacking protein cores with backbone freedom: structure prediction for coiled coils

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33767

Principles of protein folding--a perspective from simple exact models.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33767

Protein design: a hierarchic approach.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33767

Dominant forces in protein folding

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33767

Computational method for the design of enzymes with altered substrate specificity

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33767

Construction of new ligand binding sites in proteins of known structure

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33767

Automated design of the surface positions of protein helices

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33767

De novo design, expression, and characterization of Felix: a four-helix bundle protein of native-like sequence

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33767

Construction of new ligand binding sites in proteins of known structure. II. Grafting of a buried transition metal binding site into Escherichia coli thioredoxin

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33767

Design and structural analysis of alternative hydrophobic core packing arrangements in bacteriophage T4 lysozyme

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33767

Binary patterning of polar and nonpolar amino acids in the sequences and structures of native proteins

11 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.94.19.10015

Protein design by binary patterning of polar and nonpolar amino acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.94.19.10015

Molecular technology: Designing proteins and peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.94.19.10015

Metal search: a computer program that helps design tetrahedral metal-binding sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.94.19.10015

21 January 2018

Identifiers

DOI

10.1073/PNAS.94.19.10015

1 reference

11 August 2017

0 references

1 reference

PMC publication ID

33767

11 August 2017

PubMed publication ID

9294154

1 reference

PMC publication ID

33767