Mono-(2-ethylhexyl)-phthalate (MEHP) affects ERK-dependent GDNF signalling in mouse stem-progenitor spermatogonia. (Q36040706)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22564763%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

title

Mono-(2-ethylhexyl)-phthalate (MEHP) affects ERK-dependent GDNF signalling in mouse stem-progenitor spermatogonia (English)

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31 January 2020

1

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31 January 2020

Christopher J Fields

series ordinal

2

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31 January 2020

Marie-Claude Hofmann

series ordinal

4

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31 January 2020

author name string

Neeraj Joshi

series ordinal

3

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31 January 2020

language of work or name

English

0 references

publication date

27 April 2012

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31 January 2020

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31 January 2020

volume

299

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31 January 2020

issue

1

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31 January 2020

page(s)

10-19

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Effects of di(n-butyl) phthalate exposure on foetal rat germ-cell number and differentiation: identification of age-specific windows of vulnerability.

31 January 2020

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Protective effect of selenium supplementation on the genotoxicity of di(2-ethylhexyl)phthalate and mono(2-ethylhexyl)phthalate treatment in LNCaP cells.

2 October 2017

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FasL gene-deficient mice display a limited disruption in spermatogenesis and inhibition of mono-(2-ethylhexyl) phthalate-induced germ cell apoptosis

2 October 2017

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Mono-(2-ethylhexyl) phthalate-induced disruption of junctional complexes in the seminiferous epithelium of the rodent testis is mediated by MMP2

2 October 2017

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2 October 2017

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Concentrations of phthalate metabolites in milk, urine, saliva, and Serum of lactating North Carolina women

2 October 2017

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The molecular signature of spermatogonial stem/progenitor cells in the 6-day-old mouse testis.

2 October 2017

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Hematopoietic stem cell function and survival depend on c-Myc and N-Myc activity

2 October 2017

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The novel estrogen receptor, G protein-coupled receptor 30, mediates the proliferative effects induced by 17beta-estradiol on mouse spermatogonial GC-1 cell line.

2 October 2017

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Correlation of phthalate exposures with semen quality

2 October 2017

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Antagonistic effects of testosterone and the endocrine disruptor mono-(2-ethylhexyl) phthalate on INSL3 transcription in Leydig cells

2 October 2017

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Why myc? An unexpected ingredient in the stem cell cocktail

2 October 2017

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Genes involved in post-transcriptional regulation are overrepresented in stem/progenitor spermatogonia of cryptorchid mouse testes.

2 October 2017

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Mono-(2-ethylhexyl) phthalate increases spermatocyte mitochondrial peroxiredoxin 3 and cyclooxygenase 2.

2 October 2017

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Gdnf upregulates c-Fos transcription via the Ras/Erk1/2 pathway to promote mouse spermatogonial stem cell proliferation.

2 October 2017

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Differential expression of peroxiredoxin 6 in fetal rat testis following in utero exposure to di(n-butyl) phthalate

2 October 2017

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Glial cell line-derived neurotrophic factor regulation of genes essential for self-renewal of mouse spermatogonial stem cells is dependent on Src family kinase signaling

2 October 2017

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Akt mediates self-renewal division of mouse spermatogonial stem cells

2 October 2017

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Role of Src family kinases and N-Myc in spermatogonial stem cell proliferation.

2 October 2017

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Transcriptional regulation of FasL expression and participation of sTNF-alpha in response to sertoli cell injury.

2 October 2017

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Phthalate exposure and male infertility

2 October 2017

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Testicular gene expression profiling following prepubertal rat mono-(2-ethylhexyl) phthalate exposure suggests a common initial genetic response at fetal and prepubertal ages

2 October 2017

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2 October 2017

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Coordinated European investigations of semen quality: results from studies of Scandinavian young men is a matter of concern

2 October 2017

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Glial cell-line derived neurotrophic factor-mediated RET signaling regulates spermatogonial stem cell fate

2 October 2017

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Isolation of male germ-line stem cells; influence of GDNF.

2 October 2017

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2 October 2017

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Assessing human exposure to phthalates using monoesters and their oxidized metabolites as biomarkers

2 October 2017

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GDNF‐induced seminomatous tumours in mouse – an experimental model for human seminomas?

2 October 2017

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Long-Term Proliferation in Culture and Germline Transmission of Mouse Male Germline Stem Cells1

2 October 2017

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N-myc is essential during neurogenesis for the rapid expansion of progenitor cell populations and the inhibition of neuronal differentiation

2 October 2017

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Altered gene profiles in fetal rat testes after in utero exposure to di(n-butyl) phthalate

2 October 2017

1 reference

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Testicular dysgenesis syndrome: an increasingly common developmental disorder with environmental aspects

2 October 2017

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Promotion of seminomatous tumors by targeted overexpression of glial cell line-derived neurotrophic factor in mouse testis

2 October 2017

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The plasticizer diethylhexyl phthalate induces malformations by decreasing fetal testosterone synthesis during sexual differentiation in the male rat

2 October 2017

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Levels of seven urinary phthalate metabolites in a human reference population

2 October 2017

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The question of declining sperm density revisited: an analysis of 101 studies published 1934-1996

2 October 2017

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Regulation of cell fate decision of undifferentiated spermatogonia by GDNF.

2 October 2017

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Targeted disruption of the Insl3 gene causes bilateral cryptorchidism

2 October 2017

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Have sperm densities declined? A reanalysis of global trend data

2 October 2017

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Decline in semen quality among fertile men in Paris during the past 20 years

2 October 2017

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2 October 2017

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Evidence for decreasing quality of semen during past 50 years

2 October 2017

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2 October 2017

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Correlations between phthalate metabolites in urine, serum, and seminal plasma from young Danish men determined by isotope dilution liquid chromatography tandem mass spectrometry

27 July 2018

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An exposure assessment of di-(2-ethylhexyl) phthalate (DEHP) and di-n-butyl phthalate (DBP) in human semen

23 September 2018

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Comparative toxicological evaluation of phthalate diesters and metabolites in Sprague-Dawley male rats for risk assessment

23 September 2018

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Plasma phthalate levels in pubertal gynecomastia

23 September 2018

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Assessing the relevance of in vitro measures of phthalate inhibition of steroidogenesis for in vivo response

23 September 2018

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The missing niche for spermatogonial stem cells: do blood vessels point the way?

23 September 2018

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A dose response study following in utero and lactational exposure to di-(2-ethylhexyl) phthalate (DEHP): reproductive effects on adult male offspring rats.

23 September 2018

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DEHP metabolites in urine of children and DEHP in house dust

23 September 2018

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Differential effects of phthalates on the testis and the liver

23 September 2018

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Abnormal Leydig Cell aggregation in the fetal testis of rats exposed to di (n-butyl) phthalate and its possible role in testicular dysgenesis

23 September 2018

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Subcellular distribution of di-(2-ethylhexyl)phthalate in rat testis

23 September 2018

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The relationship between environmental exposure to phthalates and computer-aided sperm analysis motion parameters

23 September 2018

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Induction of apoptosis by mono(2-ethylhexyl)phthalate (MEHP) in U937 cells

23 September 2018

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Human 'testicular dysgenesis syndrome': a possible model using in-utero exposure of the rat to dibutyl phthalate

23 September 2018

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Role of oxidative stress in germ cell apoptosis induced by di(2-ethylhexyl)phthalate

23 September 2018

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Participation of the Fas-signaling system in the initiation of germ cell apoptosis in young rat testes after exposure to mono-(2-ethylhexyl) phthalate.

23 September 2018

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Effects of relatively low levels of mono-(2-ethylhexyl) phthalate on cocultured Sertoli cells and gonocytes from neonatal rats

23 September 2018

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Decreasing quality of semen

23 September 2018

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Urinary phthalate monoesters concentration in couples with infertility problems

23 September 2018

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12 December 2020

Plasticizers in total diet samples, baby food and infant formulae

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Stem cells in the testis

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12 December 2020

Changes in hepatic dolichol and dolichyl monophosphate caused by treatment of rats with inducers of the endoplasmic reticulum and peroxisomes and during ontogeny

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Mono-(2-ethylhexyl) Phthalate Rapidly Alters both Sertoli Cell Vimentin Filaments and Germ Cell Apoptosis in Young Rat Testes

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The Fas system is a key regulator of germ cell apoptosis in the testis

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12 December 2020

What are the sources of exposure to eight frequently used phthalic acid esters in Europeans?

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12 December 2020

Acute and long-term effects of in utero exposure of rats to di(n-butyl) phthalate on testicular germ cell development and proliferation

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Biphasic effects of postnatal exposure to diethylhexylphthalate on the timing of puberty in male rats

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10.1016/J.TOX.2012.04.011

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22564763%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22564763%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

PubMed publication ID

22564763

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22564763%20AND%20SRC:MED&resulttype=core&format=json