Collagen Q and anti-MuSK autoantibody competitively suppress agrin/LRP4/MuSK signaling (Q36044172)

11 August 2017

Collagen Q and anti-MuSK autoantibody competitively suppress agrin/LRP4/MuSK signaling (English)

1 reference

11 August 2017

1 reference

11

1 reference

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2 June 2020

author name string

Kenji Otsuka

1

1 reference

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2 June 2020

Mikako Ito

2

1 reference

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2 June 2020

Bisei Ohkawara

3

1 reference

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2 June 2020

Akio Masuda

4

1 reference

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2 June 2020

Yu Kawakami

5

1 reference

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2 June 2020

Ko Sahashi

6

1 reference

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2 June 2020

Hiroshi Nishida

7

1 reference

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2 June 2020

Naoki Mabuchi

8

1 reference

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2 June 2020

Akemi Takano

9

1 reference

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2 June 2020

Andrew G Engel

10

1 reference

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2 June 2020

language of work or name

English

0 references

publication date

10 September 2015

1 reference

11 August 2017

1 reference

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2 June 2020

volume

5

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2 June 2020

page(s)

13928

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Creative Commons Attribution 4.0 International

2 June 2020

copyright license

start time

10 September 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Impaired Synaptic Development, Maintenance, and Neuromuscular Transmission in LRP4-Related Myasthenia

1 reference

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MuSK frizzled-like domain is critical for mammalian neuromuscular junction formation and maintenance.

2 October 2017

1 reference

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Guidelines for pre-clinical animal and cellular models of MuSK-myasthenia gravis.

2 October 2017

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HnRNP C, YB-1 and hnRNP L coordinately enhance skipping of human MUSK exon 10 to generate a Wnt-insensitive MuSK isoform

2 October 2017

1 reference

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Effects of the ß2-adrenoceptor agonist, albuterol, in a mouse model of anti-MuSK myasthenia gravis

2 October 2017

1 reference

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MuSK IgG4 autoantibodies cause myasthenia gravis by inhibiting binding between MuSK and Lrp4.

2 October 2017

1 reference

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MuSK myasthenia gravis IgG4 disrupts the interaction of LRP4 with MuSK but both IgG4 and IgG1-3 can disperse preformed agrin-independent AChR clusters

2 October 2017

1 reference

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LRP4 third β-propeller domain mutations cause novel congenital myasthenia by compromising agrin-mediated MuSK signaling in a position-specific manner

2 October 2017

1 reference

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Pyridostigmine but not 3,4-diaminopyridine exacerbates ACh receptor loss and myasthenia induced in mice by muscle-specific kinase autoantibody

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4564764

Developmental consequences of the ColQ/MuSK interactions

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4564764

Neuromuscular junction acetylcholinesterase deficiency responsive to albuterol.

2 October 2017

1 reference

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Biglycan is an extracellular MuSK binding protein important for synapse stability

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4564764

Protein-anchoring strategy for delivering acetylcholinesterase to the neuromuscular junction

2 October 2017

1 reference

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Anti-MuSK autoantibodies block binding of collagen Q to MuSK.

2 October 2017

1 reference

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Development of a highly sensitive diagnostic assay for muscle-specific tyrosine kinase (MuSK) autoantibodies in myasthenia gravis

2 October 2017

1 reference

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Agrin binds to the N-terminal region of Lrp4 protein and stimulates association between Lrp4 and the first immunoglobulin-like domain in muscle-specific kinase (MuSK)

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4564764

Beneficial effects of albuterol in congenital endplate acetylcholinesterase deficiency and Dok-7 myasthenia

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4564764

Wnt signaling during synaptic development and plasticity

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4564764

Biglycan recruits utrophin to the sarcolemma and counters dystrophic pathology in mdx mice

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4564764

Autoimmune mediated neuromuscular junction defects

2 October 2017

1 reference

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To build a synapse: signaling pathways in neuromuscular junction assembly

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4564764

ColQ controls postsynaptic differentiation at the neuromuscular junction

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4564764

Clinical findings in MuSK-antibody positive myasthenia gravis: a U.S. experience

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4564764

Crystal Structure of the Frizzled-Like Cysteine-Rich Domain of the Receptor Tyrosine Kinase MuSK

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4564764

LRP4 serves as a coreceptor of agrin

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4564764

Lrp4 is a receptor for Agrin and forms a complex with MuSK

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4564764

Crystal structure of the agrin-responsive immunoglobulin-like domains 1 and 2 of the receptor tyrosine kinase MuSK

2 October 2017

1 reference

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MuSK is required for anchoring acetylcholinesterase at the neuromuscular junction

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4564764

Detection and characterization of MuSK antibodies in seronegative myasthenia gravis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4564764

Two different heparin-binding domains in the triple-helical domain of ColQ, the collagen tail subunit of synaptic acetylcholinesterase

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4564764

Auto-antibodies to the receptor tyrosine kinase MuSK in patients with myasthenia gravis without acetylcholine receptor antibodies

2 October 2017

1 reference

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Acetylcholinesterase clustering at the neuromuscular junction involves perlecan and dystroglycan

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4564764

Genetic analysis of collagen Q: roles in acetylcholinesterase and butyrylcholinesterase assembly and in synaptic structure and function

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4564764

Targeted disruption of the biglycan gene leads to an osteoporosis-like phenotype in mice

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4564764

Human endplate acetylcholinesterase deficiency caused by mutations in the collagen-like tail subunit (ColQ) of the asymmetric enzyme

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4564764

The Frizzled CRD domain is conserved in diverse proteins including several receptor tyrosine kinases

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4564764

Muscle-specific trk-related receptor with a kringle domain defines a distinct class of receptor tyrosine kinases

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4564764

Receptor tyrosine kinase specific for the skeletal muscle lineage: expression in embryonic muscle, at the neuromuscular junction, and after injury

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4564764

C-terminal and heparin-binding domains of collagenic tail subunit are both essential for anchoring acetylcholinesterase at the synapse

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4564764

The mammalian gene of acetylcholinesterase-associated collagen

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4564764

Mutations in the C-terminal domain of ColQ in endplate acetylcholinesterase deficiency compromise ColQ-MuSK interaction

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4564764

Muscle-specific kinase myasthenia gravis IgG4 autoantibodies cause severe neuromuscular junction dysfunction in mice

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4564764

Divalent and monovalent autoantibodies cause dysfunction of MuSK by distinct mechanisms in a rabbit model of myasthenia gravis.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4564764

Antibodies against muscle-specific kinase impair both presynaptic and postsynaptic functions in a murine model of myasthenia gravis.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4564764

An ATF2-based luciferase reporter to monitor non-canonical Wnt signaling in Xenopus embryos

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4564764

Patient autoantibodies deplete postsynaptic muscle-specific kinase leading to disassembly of the ACh receptor scaffold and myasthenia gravis in mice.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4564764

Pre- and postsynaptic neuromuscular junction abnormalities in musk myasthenia

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4564764

Clinical and experimental features of MuSK antibody positive MG in Japan.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4564764

MRI and clinical studies of facial and bulbar muscle involvement in MuSK antibody-associated myasthenia gravis

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4564764

Nonresponsiveness to anticholinesterase agents in patients with MuSK-antibody-positive MG.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4564764

Congenital endplate acetylcholinesterase deficiency responsive to ephedrine

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4564764

Acetylcholine receptors loss and postsynaptic damage in MuSK antibody-positive myasthenia gravis

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4564764

Are MuSK antibodies the primary cause of myasthenic symptoms?

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4564764

Clinical aspects of MuSK antibody positive seronegative MG.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4564764

Clinical correlates with anti-MuSK antibodies in generalized seronegative myasthenia gravis.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4564764

Localization of disulfide bonds in the frizzled module of Ror1 receptor tyrosine kinase

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4564764

The Wnt receptor CRD domain is also found in MuSK and related orphan receptor tyrosine kinases

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4564764

Evidence for a prostate cancer susceptibility locus on the X chromosome.

23 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FSREP13928

Antibodies against Wnt receptor of muscle-specific tyrosine kinase in myasthenia gravis

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26355076

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

MuSK levels differ between adult skeletal muscles and influence postsynaptic plasticity

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26355076

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Myasthenia gravis. Study of humoral immune mechanisms by passive transfer to mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26355076

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/SREP13928

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26355076%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26355076%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

PubMed publication ID

26355076

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26355076%20AND%20SRC:MED&resulttype=core&format=json