Locally expressed IGF1 propeptide improves mouse heart function in induced dilated cardiomyopathy by blocking myocardial fibrosis and SRF-dependent CTGF induction. (Q36051055)

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English	Locally expressed IGF1 propeptide improves mouse heart function in induced dilated cardiomyopathy by blocking myocardial fibrosis and SRF-dependent CTGF induction.	scientific article

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31 January 2020

Locally expressed IGF1 propeptide improves mouse heart function in induced dilated cardiomyopathy by blocking myocardial fibrosis and SRF-dependent CTGF induction (English)

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31 January 2020

dilated cardiomyopathy

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Mathias Mericskay

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Nadia Rosenthal

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Jean-Francois Decaux

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Melissa Touvron

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Brigitte Escoubet

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Aude Angelini

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Luciane Lamotte

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Maria Paola Santini

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Dominique Daegelen

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David Tuil

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5 April 2012

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Disease Models & Mechanisms

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5

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31 January 2020

481-491

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31 January 2020

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18 May 2021

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Cleavage of serum response factor mediated by enteroviral protease 2A contributes to impaired cardiac function

1 reference

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2 October 2017

Malignant and benign mutations in familial cardiomyopathies: insights into mutations linked to complex cardiovascular phenotypes.

1 reference

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2 October 2017

Local IGF-1 isoform protects cardiomyocytes from hypertrophic and oxidative stresses via SirT1 activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380711

2 October 2017

CTGF promotes inflammatory cell infiltration of the renal interstitium by activating NF-kappaB.

1 reference

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2 October 2017

miR-133 and miR-30 regulate connective tissue growth factor: implications for a role of microRNAs in myocardial matrix remodeling

1 reference

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2 October 2017

Involvement of connective tissue growth factor (CTGF) in insulin-like growth factor-I (IGF1) stimulation of proliferation of a bovine mammary epithelial cell line

1 reference

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2 October 2017

Serum response factor micromanaging cardiogenesis

1 reference

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2 October 2017

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2 October 2017

Actin-dependent regulation of connective tissue growth factor

1 reference

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2 October 2017

Fibrosis in heart disease: understanding the role of transforming growth factor-beta in cardiomyopathy, valvular disease and arrhythmia

1 reference

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2 October 2017

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1 reference

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2 October 2017

Defining the mammalian CArGome

1 reference

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2 October 2017

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380711

2 October 2017

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380711

2 October 2017

Administration of insulin-like growth factor-1 (IGF-1) improves both structure and function of delta-sarcoglycan deficient cardiac muscle in the hamster.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380711

2 October 2017

Expression of insulin-like growth factor I by activated hepatic stellate cells reduces fibrogenesis and enhances regeneration after liver injury.

1 reference

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2 October 2017

Restricted inactivation of serum response factor to the cardiovascular system

1 reference

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2 October 2017

Organization of fibroblasts in the heart

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2 October 2017

Targeted inactivation of serum response factor in the developing heart results in myocardial defects and embryonic lethality

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2 October 2017

Gene regulation of connective tissue growth factor: new targets for antifibrotic therapy?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380711

2 October 2017

Connective-tissue growth factor (CTGF) modulates cell signalling by BMP and TGF-beta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380711

2 October 2017

Remodeling the intercalated disc leads to cardiomyopathy in mice misexpressing cadherins in the heart

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380711

2 October 2017

Alterations at the intercalated disk associated with the absence of muscle LIM protein

1 reference

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2 October 2017

Insulin-like growth factor I and cardiac performance in heart failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380711

2 October 2017

The Ki-67 protein: from the known and the unknown

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2 October 2017

Insulin-like growth factor I as a cardiac hormone: physiological and pathophysiological implications in heart disease

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2 October 2017

Serum response factor is essential for mesoderm formation during mouse embryogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380711

2 October 2017

Growth and differentiation of C2 myogenic cells are dependent on serum response factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380711

2 October 2017

Insulin-like growth factor-1 enhances ventricular hypertrophy and function during the onset of experimental cardiac failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380711

2 October 2017

Regulation of pro-inflammatory and pro-fibrotic factors by CCN2/CTGF in H9c2 cardiomyocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380711

11 July 2018

Paracrine control of oligodendrocyte differentiation by SRF-directed neuronal gene expression.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380711

23 September 2018

Mosaic inactivation of the serum response factor gene in the myocardium induces focal lesions and heart failure.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380711

23 September 2018

Increased connective tissue growth factor relative to brain natriuretic peptide as a determinant of myocardial fibrosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380711

23 September 2018

Local expression of IGF-1 accelerates muscle regeneration by rapidly modulating inflammatory cytokines and chemokines.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380711

23 September 2018

Temporally controlled onset of dilated cardiomyopathy through disruption of the SRF gene in adult heart

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380711

23 September 2018

Increased expression of alternatively spliced dominant-negative isoform of SRF in human failing hearts

1 reference

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23 September 2018

Lack of desmin results in abortive muscle regeneration and modifications in synaptic structure

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23 September 2018

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1 reference

https://pubmed.ncbi.nlm.nih.gov/22563064

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based on heuristic

inferred from PubMed ID database lookup

Simultaneous expression of skeletal muscle and heart actin proteins in various striated muscle tissues and cells. A quantitative determination of the two actin isoforms

1 reference

https://pubmed.ncbi.nlm.nih.gov/22563064

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibitory cardiac transcription factor, SRF-N, is generated by caspase 3 cleavage in human heart failure and attenuated by ventricular unloading

1 reference

https://pubmed.ncbi.nlm.nih.gov/22563064

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early postnatal cardiac changes and premature death in transgenic mice overexpressing a mutant form of serum response factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/22563064

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential cardiac effects of growth hormone and insulin-like growth factor-1 in the rat. A combined in vivo and in vitro evaluation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22563064

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Posttranslational modifications of the KI-67 protein coincide with two major checkpoints during mitosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22563064

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cardiac-specific IGF-1 expression attenuates dilated cardiomyopathy in tropomodulin-overexpressing transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22563064

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1242/DMM.009456

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31 January 2020

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31 January 2020

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31 January 2020

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